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hanks to his herculean physique, John Cena has enjoyed a decades-long career as a professional wrestler, actor, and rapper. And he has no plans to give up on his gains as he ages.

In a recent interview with Howard Stern, Cena says that hes never taken testosterone replacement therapy (TRT) or anabolic steroids to bulk upbut hes open to the former when his natural testosterone levels start to dip.

Im not ruling (TRT) out. Therell come a time, Cena told Stern. I get my bloodwork done three times a year, and my testosterone is fantastic for a [nearly] 47-year-old.

Cena believes that maintaining healthy testosterone levels promotes longevity and makes it easier to recover post-workout. And hes right. Health professionals suggest theres a link between T levels and lifespan.

While low testosterone may not increase your risk for early death directly all-cause mortality risk increases in men with lower testosterone levels, says James Staheli, D.O.

Conditions linked to low testosterone may be the culprit. Studies show that clinically low T is linked to a higher risk of diabetes, metabolic syndrome, cardiovascular disease, osteoporosis, sexual dysfunction, depression, and dementia (1).

If left unchecked, many of these conditions can limit your healthspan and lifespan.

Research also suggests having a healthy testosterone level for your age] may support skeletal muscle tissue growth, which can help reduce injury risk and help your muscles recover better between workouts (2). Dodging injury and maintaining a healthy amount of muscle can extend your lifespan, too, studies suggest (3).

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Why John Cena is Considering Testosterone Replacement Therapy - The Edge

Some men naturally have a lower testosterone level than others. Others have low testosterone due to age, genetics, lifestyle, or dieting. While low testosterone levels can be devastating to any mans body and mind in itself, there are ways of boosting testosterone production naturally that dont involve any medication or other artificial substances (or expensive TRT, testosterone replacement therapy).

Yes, thats true! Boosting testosterone levels without resorting to anabolic steroids is possible. Today, some of the worlds best natural testosterone boosters claim to raise testosterone levels without the side effects of anabolic steroids. By taking these testosterone supplements daily, you can purportedly support healthy male testosterone, giving you high energy levels, weight loss results, and muscle gain.

So, if you are looking for the best testosterone boosters for 2024? Which testosterone-boosting supplements live up to the hype? Find out everything you need to know today in our guide to testosterone booster supplements.

Our editorial team interviewed manufacturers, analyzed labels, and read countless clinical trials to determine the best testosterone supplements of 2024. Below are our rankings of the best testosterone boosters of this year.

Lets jump right into the heart of the matter and review the top best testosterone boosters for men looking to naturally boost testosterone levels:

Product Classification

Whats in it: These premium testosterone pills are formulated with the help of Ashwagandha, Fenugreek, Zinc, L-Arginine HCL, Panax Ginseng, D-aspartic acid, Vitamin D3, Garlin, and Magnesium.

Supplement Features:

Serving Instructions: Take four capsules with a glass of water daily

Check Official Website: Testosil.com

Testosil stands unchallenged as the best natural testosterone booster available in the market today to promote testosterone production. Leveraging a potent testosterone booster formulated with patented ingredients, it promises an impressive increase of up to 434% in testosterone levels, more than what exercise alone can deliver.

Sourced from FDA-registered and inspected facilities and created following cGMP-certified manufacturing processes, Testosil offers a safer alternative to synthetic testosterone boosters, aiding in harmonizing hormone balance and enhancing sexual function.

Complementing a healthy diet it empowers men to boost testosterone naturally, fostering greater muscle size and strength, as evidenced in a groundbreaking study. Choose Testosil, the epitome of potency and reliability, and redefine the boundaries of your physical and sexual well-being.

Product Classification

Whats in it: Trigonella foenum-graecum and Furosap

Supplement Features:

Serving Instructions: Consume one pill every day

Check Official Website: Primegenix.com

Last on our list, PrimeGENIX Testodren has recently launched a formula for boosting free testosterone levels in the body. With Testodren, you can choose a healthy and natural alternative to testosterone products that only partially work and leave destruction behind. The product is completely safe because it has no side effects. It is a great option available in the testosterone supplement market.

Product Classification

Whats in it: With Testogen testosterone pills, you get a combination of fenugreek, D-aspartic acid, Nettle Leaf Extract, Zinc, Vitamin D3, and other herbal extracts, minerals, and nutrients linked to a higher testosterone level.

Supplement Features:

Serving Instructions: It is best to take 4 Testogen pills daily, 20 minutes before breakfast.

Check Official Website: Tesogen.com

Testogen is the best testosterone booster supplement that claims to target energy levels, muscle growth, sex drive, and overall male performance. Some people take Testogen to lose weight. Others take it to accelerate lean muscle mass. Some just want to raise their sex drive. Several ingredients in these best testosterone pills further ensure the healthy production of sex hormone-binding globulin to balance androgens and estrogens.

Testogen contains zero steroids; therefore, it will naturally increase testosterone levels in men. Testogen is manufactured by a well-known American company. According to the makers of this natural testosterone booster, you will notice health improvements within a fortnight of beginning use.

Product Classification

Whats in it: Prime Male contains strong doses of Vitamin D3, Vitamin K2, Vitamin B6, Magnesium, BioPerine, Zinc, D-Aspartic Acid Calcium Chelate, Asian Red Ginseng, Luteolin, Mucuna Pruriens, Nettle Root Extract, and Boron (as boron amino acid chelate)

Supplement Features:

Serving Instructions: After a meal, take 4 capsules of Prime Male every day

Check Official Website: Primemale.com

Prime Male testosterone boosting supplement is one of the fanciest formulas on this list, delivering a higher dose of proven testosterone-boosting ingredients than most of its competitors. The makers of Prime Male claim their formula could raise testosterone as high as 42% in under two weeks. It also has a genuine celebrity endorsement from Dolph Lundgren, of all people.

The formula contains a potent ingredient called Luteolin, which balances the luteinizing hormone and follicle-stimulating hormone to increase testosterone production naturally.

Priced at $69 per bottle, its not as cheap as other testosterone-boosting supplements on this list, but Prime Male emphasizes good value by using stronger doses of active natural ingredients. Advertised benefits include higher energy and libido, improved lean muscle mass, controlled blood sugar levels, and better overall performance, among other health benefits.

Product Classification

Whats in it: The manufacturer claims that each serving of TestoPrime contains 8,000mg of Panax ginseng, 2,000mg of D-aspartic acid, 800mg of fenugreek extract, and 668 mg of ashwagandha extract, all of which are the strongest doses on this list.

Supplement Features:

Serving Instructions: Consume four capsules of Testoprime before breakfast each day

Check Official Website: Tesoprime.com

Testo Prime testosterone boosting supplement contains some of the strongest doses on this list. To put that dosage in perspective, we dont see a dosage this strong, even with scoops of protein powder.

Testo Prime has packed an unusually strong dose of only natural ingredients into each capsule of its formula. By taking one four-capsule serving of Testo Prime daily, you can purportedly lose weight, increase lean muscle mass, and raise testosterone, among other noticeable health benefits. It has got amazing customer reviews to impress us.

Product Classification

Whats in it: The blend includes Fenugreek Extract, D-Aspartic Acid, Vitamins D, K2, and B6, Magnesium, Oyster Extract, Ginseng, and Zinc to increase testosterone levels naturally.

Supplement Features:

Serving Instructions: Take 4 capsules per day in an instructed time gap to boost testosterone levels

Check Official Website: Testofuel.com

The makers of TestoFuel advertise their formula as an anabolic support complex, suggesting it supports testosterone by targeting your natural anabolism. Using only natural ingredients, TestoFuel claims to offer optimal testosterone levels with D-aspartic acid, vitamin D, and even oyster extract, among other proven compounds.

Each serving of TestoFuel testosterone-boosting supplement works to help with sex drive, virility, testosterone, muscle growth, body fat burning, and more. You take four capsules per serving to support testosterone.

Product Classification

Whats in it: Testolab Pro fuels up your testosterone with D-Aspartic Acid, Oyster Extract, Ginseng, Fenugreek, Magnesium, Vitamin B, Vitamin K2, Zinc

Supplement Features:

Serving Instructions: Consume 2 capsules in the morning and 2 in the evening to support healthy testosterone levels

Check Official Website: Testolabpro.com

TestoLab Pro delivers 120 capsules of testosterone-boosting power in each bottle. Each bottle includes natural ingredients to protect, sustain, and potentiate testosterone circulating through your body. Like other testosterone supplements, TestoLab Pro claims to specifically improve free testosterone levels and boost luteinizing hormone production.

Testosterone is only useful when circulating through your bloodstream. With TestoLab Pro, you get effective natural ingredients to support weight loss, muscle-building, stress response, sex drive, and even bone strength, among other unique effects.

Product Classification

Whats in it: HunterTest testosterone pills contain the following natural ingredients: Asian Ginseng, Ashwagandha, Boron Chelate, D-aspartic acid, Vitamin K2, Vitamin D, Zinc, Indole-3-Carbinol, and Magnesium.

Supplement Features:

Serving Instructions: Take 6 capsules every day with a glass of water

Check Official Website: Hunterevolve.com

Hunter Tests stylish packaging masks a supplement with strong doses of multiple active ingredients linked to healthy testosterone levels. The customer reviews section says everything. We like the natural testosterone booster Hunter Test because it combines vitamins and minerals crucial for testosterone production with herbal extracts linked to libido and sex drive.

Together, these best testosterone booster pills could help you support testosterone production from multiple angles. Thats why the makers of Hunter Test describe their formula as a total testosterone-boosting package. If you like stylish packaging, then its also tough to beat Hunter Test.

Product Classification

Whats in it: Boswellia extract (Frankincense), Ashwagandha, Shilajit, Tongkat Ali, Korean Red Ginseng, Magnesium, Zinc, Vitamin D, and Vitamin B6

Supplement Features:

Serving Instructions: Experts recommend taking 2 capsules daily

Check Official Website: SilentMalePlague.com

Zenith Labs makes an effective testosterone booster called Barbarian XL. The supplement is also one of the few on this list that was genuinely formulated and approved by a doctor. Dr. Ryan Shelton is the Chief Medical Officer for Zenith Labs, and he used his experience in naturopathy to create the Barbarian XL formula.

Barbarian XL features unique ingredients we dont see with other testosterone boosters on this list, and it could work differently by targeting different pathways. Barbarian XL contains Boswellia resin extract, ashwagandha, shilajit, ginseng, and other ingredients traditionally used in various fields of Asian medicine.

Product Classification

Whats in it: Tongkat Ali, L-Norvaline, Avena Sativa, Cordyceps Sinensis, Rhodiola Rosea, and Tribulus Terrestris are all included in T20 to help boost testosterone levels.

Supplement Features:

Serving Instructions: Swallow 2 capsules every day for at least 3 months

Check Official Website: Saveyourmojo.com

Dont let JayLab Pro T20s bland packaging fool you: the supplement claims to boost your testosterone and turn back your body clock by 20 years with just 30 seconds of supplementation per day. By taking two capsules of T20 daily, you can give your body the ingredients it needs to support testosterone production. T20 uses ingredients we expect to see in a testosterone booster, including Tongkat Ali and Tribulus Terrestris.

The natural testosterone booster also contains unique ingredients and mechanisms we dont always expect to see, including L-norvaline and Avena sativa for targeting blood flow. These ingredients could enhance vitality from multiple angles. Instead of just boosting testosterone, T20 could support blood flow and other benefits. At under $40, its also one of the most affordable natural testosterone boosters on our list.

Product Classification

Whats in it: Each serving of Testo-Max includes D-aspartic acid, vitamin D3, magnesium, Bioperine(05% Piperine), Korean red ginseng, nettle leaf extract, fenugreek, and other herbal extracts, vitamins, minerals, and nutrients associated with testosterone production in the male body.

Supplement Features:

Serving Instructions: Take 4 capsules before 20 minutes of breakfast

Check Official Website: Crazybulk.com

The last strongest testosterone booster, CrazyBulk, is best known for its bodybuilding supplements, including formulas that help with cutting, bulking, and boosting strength. With Testo-Max, the supplement improves bodybuilding results from a different angle: by supporting testosterone production. It has Nettle leaf extract that improves blood flow and healthy testosterone levels by preventing the free testosterone from binding to sex hormone-binding globulin.

CrazyBulks Testo-Max is advertised as a strength and energy supplement and a natural alternative to higher-powered products. Its part of CrazyBulks Mass Series.

Product Classification

Whats in it: Fenugreek Seed Extract, D-aspartic Acid, ZMA, Vitamin K2, Vitamin B6 (Pyridoxine HCl), Zinc, Magnesium, and Vitamin D3

Supplement Features:

Serving Instructions: Swallow 4 capsules each day in two doses

Check Official Website: TestRX.com

TestRX is a natural testosterone supplement that uses vitamin D, vitamin B6, and other vitamins and minerals crucial for male sexual health. TestRX emphasizes similar benefits to competing supplements. It has Vitamin D3, which is a fat-soluble vitamin to increase the absorption of calcium and phosphorus.

By taking TestRX daily, you can purportedly put on stacks of lean, hard muscle mass at any age. The supplement is primarily advertised to men who want to increase muscle mass, muscle tone, and burn body fat. However, its also marketed as a sexual health supplement and libido booster that raises free testosterone levels. With multiple effects and angles, TestRX aims to be the best testosterone booster for men of any age.

Product Classification

Whats in it: With Testo 911, you get a formula with modest doses of magnesium, Diindolylmethane (DIM), Eurycoma Longifolia, zinc, Rhodiola Rosea, and other ingredients.

Supplement Features:

Serving Instructions: Take 2 capsules of Testo 911 every day

Check Official Website: Testo911.com

Testo 911 is one of many 911 supplements from PhytAge Labs targeting different health and wellness goals. The company is known for its unusual marketing campaigns and dramatic sales videos. PhytAge Labs claims their formula will naturally boost testosterone levels, increase energy levels, support blood flow, reduce inflammation, and aid in a healthy metabolism, among other benefits. Just take it daily to enjoy all of these benefits and more.

Testosterone booster companies make similar promises: they all claim to support healthy testosterone, increase muscle growth, and give you the energy and sex drive you had as a younger man.

However, few testosterone boosters live up to those promises. To separate the best and worst testosterone booster supplements from one another, we considered all of the following factors in our rankings:

The goal of the best testosterone booster is to replicate the effects of anabolic steroids using legal, natural, safe ingredients. Some testosterone boosters use vitamins and minerals. Others use herbal extracts or amino acids. Some ingredients are backed by real scientific evidence, while others are not.

Want to know a secret? The two most important testosterone-boosting ingredients are vitamin D and zinc, both of which are available in an average multivitamin. You can find multivitamins for less than $10, while the testosterone boosters above cost $40 and up. Thats why we considered the uniqueness of the formula in our rankings. Youre buying the best testosterone booster for more than just zinc and vitamin D.

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Top 13 Strongest Testosterone Boosters Ranked: Best Brands to Buy in 2024 | HeraldNet.com - The Daily Herald

Alan Ritchson is finally a success story, though it took many more years than he expected. At 41 years old, the Reacher star is a testament to perseverance in the industry, and learning from your own mistakes.

Speaking in a new interview with Men's Health, the actor shares that he was super-confident his big breakthrough moment had come when he starred in Spike TV's (now Paramount) 2010 comedy, Blue Mountain State. He even got a follow-up film out of the project.

"I just sort of expected that there would be a cornucopia of comedies for me to choose from," he said. "And nobody really wanted to see me for anything." This was five years after scoring the role of Aquaman on Smallville didn't land him any superhero or action roles.

He did get a shot at another superhero, but admits that he didn't take it seriously enough. At more than six feet tall and ruggedly handsome with light hair, RItchson thought he was a lock for Marvel's Thor when he walked into a 2011 audition.

"I didnt take it seriously, he said of the audition. I was like, Theyll throw me the part if I look like the guy; nobody really cares about acting." He would ultimately lose the role to Chris Hemsworth, who continues in it to this day.

To make matters worse for the actor, still more than a decade from his own action breakthrough, his people were informed that the role had been his to lose. Apparently, he was a lock for it, but he'd failed to show them he had "the craft."

After that misstep, Ritchson took "the craft" of acting more seriously, enrolling in classes, and spent a decade settling for smaller roles in projects like Black Mirror, Brooklyn Nine-Nine. Finally, he got his superhero role in Titans as Hawk from 2019 to 2021. From there, he moved onto the lead position of Reacher, and now finds himself at a whole new level.

"I had about 50 offers the weekend after season 1 of Reacher opened," he said. "I knew my life had changed."

After working relentlessly through the first season of the hit Prime Video series, Ritchson was told he'd lost too much weight. Dealing with an injured shoulder and with time before Season 2, a doctor recommended testosterone-replacement therapy.

Saying he has little patience for any pushback about TRT, Ritchson said it has helped him keep the weight he wants on. At the same time, he acknowledged what he heard from someone, that it is "steroids with a doctor's note."

"I guess it is," he acknowledged. "I didnt even know that it was considered an anabolic steroid to some people. It was just: There was a hormone that was missing for me, and I needed it."

On top of managing his physical health, Ritchson has taken responsibility for his mental health, as well, since being diagnosed with bipolar disorder at 36 years old. Part of that includes seeing a psychiatrist weekly and being open with his wife and assistant, who know how to help see symptoms.

He said the symptoms are usually somewhat mild -- and sometimes even humorous -- when he's at home. An example he brought up was he'll be feeling, "I gotta find a perfectly white pair of shoes that look like a tennis shoe but arent." Then, three days later, "eight pairs of shoes show up that are all identical."

At work, he said it manifests more as a strive toward perfection. "When Im manic and I feel like something isnt living up to its best potential, it usually comes out in a verynot in a mean waybut in a this has to be better way. Like a very, almost obsessive this has to be better.

In another instance, he said that his manic episodes actually pushed a stunt coordinator to resign after the first season (they have since returned). When he was urged not to do a fight scene, he pushed back hard. "I was like, 'I'm doing the f--king stunt!" Ritchson said.

When he's feeling depressive, conversely, he said it's not even usually noticed while working "because I am so focused," he said it "could go weeks without people even knowing I feel a certain way."

What he's found in the years since his diagnosis is a sense of purpose, and the power of being open about his own experiences. Ritchson revealed that he was actually haunted by suicidal thoughts five years go, but then he started talking about his mental health on platforms like his YouTube channel and InstaChurch.

It's the thought that his experience could touch others and help them feel less alone in their own situations that helps him to feel less alone in his.

He's also found help in meditation, which he described as being "about manually shifting back into a calmer brain state." And then there's prayer and his 15 minutes of alone time in the sauna. "That's Zen time," he said.

Thanks to his work on Reacher, Ritchson has found himself being taken more seriously as an actor, and seeing offers for dramatic projects. His schedule has been packed tight, too.

On top of his hit show, Ritchson appeared in Fast X and has roles in two upcoming films, Ordinary Angels and The Ministry of Ungentlemanly Warfare. After years of reaching for it, it certainly looks like Ritchson has finally achieved his dream.

If you or someone you know is struggling with depression or has had thoughts of harming themselves or taking their own life, get help. The National Suicide Prevention Lifeline (1-800-273-8255) provides 24/7, free, confidential support for people in distress

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Alan Ritchson on Blowing Thor Audition, Taking Testosterone, Living with Bipolar Disorder - TooFab

People today want to make the most of these substances for their benefits. Winstrol is a common anabolic steroid. It increases muscle size and power and lowers fat in an 8-week course. Many bodybuilding enthusiasts like Winstrol steroid because it makes their muscles harder, boosts their energy, and cuts down their body fat. Anabolic steroids have been used by people for a long time, sometimes without knowing it. They use these substances to improve their energy, focus, muscle size, fat loss, and more.

1#. [OFFICIAL WEBSITE] Click Here To Buy This Winstrol From Crazy Bulk

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In this course, we will tell you everything about Winstrol. How does it affect your body? Why is it good for your fitness goals? By the end of this, you will know its pros, cons, and overall impact on your body.

Winstrol Cycle

The usual cycle for taking it and seeing results is from six to eight weeks. It might change a little depending on your weight, but the general rule is to not take it for more than 8 weeks.

Winstrol is a strong substance that can show results in two weeks.

Experts say you should not take it for more than 8 weeks, because it can hurt you after that.

You can take Winstrol differently depending on what you want from it. Some cycles can be one week, three weeks, or eight weeks, depending on your goals.

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Boost Your Performance with Winsol - The Best Winstrol Substitute at a Lower Price!

If you want a natural and safe way to improve your fitness performance, you might want to try Winsol, a legal substitute for Winstrol, a common steroid. Winsol is a supplement for building muscles that helps you grow lean muscle and burn fat and makes you stronger and faster.

How it works Winsol is a natural supplement that works like Winstrol but without bad side effects. Winsol makes your metabolism faster, improves your blood flow, and keeps your lean muscle. It also helps you get rid of water and fat, making you look more sharp and ripped.

Winsol Ingredients

Acetyl-L-Carnitine: This amino acid helps your body burn fat and makes you more focused and clear-headed.

Choline: This nutrient helps your brain and muscles work better. It also helps you stay awake and motivated.

Wild Yam Root: This plant extract is a natural source of DHEA, a hormone that controls your testosterone levels. This can help you grow muscle and strength.

DMAE: This compound is found in fish and seafood. It makes your brain and memory better and reduces swelling and muscle pain.

Safflower Oil Powder: This oil is rich in omega-6 fats that help your heart, lower swelling, and make your skin and hair healthy.

Winstrol Cycle Dosage

During the 6-8 weeks of its cycle, the usual dosage is from 20-80 mg to get rid of fat in your muscles. Some people take about 100 mg per day to build and keep muscle mass.

But the general tip is to take about 50 mg to grow your muscles and keep them. On the other hand, 75 mg is good for making your muscles stronger and your workouts more lively.

Winsol Benefits

More Fat Burning: Your metabolism gets faster, allowing you to burn more calories and fat. Your body shape can get better, and you can lose weight.

Better Muscle Definition: It helps you keep lean muscle while losing fat. This can help you get a more shaped and defined look.

Better Endurance: It makes more oxygen go to your muscles, improving your stamina and endurance during workouts. This can help you work out harder and longer.

Better Vascularity: It makes your blood flow and nitric oxide better, increasing vascularity. This can make your veins more noticeable and give you a more muscular look.

"Winsol Benefits and Drawbacks

Benefits:

A Natural, Legal, and Safe Alternative to Winstrol. Good for Both Men and Women, Improving Body Shape and Performance. No Need for Prescription or Injections; Just Take It by Mouth. Happy Customers and Good Reviews. 60-Day Money-Back Guarantee.

Drawbacks:

A Bit Costly Compared to Other Supplements in the Market. Only Available on the Official Website of CrazyBulk.

Winsol is a strong supplement for bodybuilding that can help you lose fat, gain muscle, and perform better. It is made of natural ingredients that act like Winstrol without causing any bad side effects.

If you want a safe and legal way to improve your body and fitness level, Winsol might be the supplement for you.

Winstrol Steroid

Mainly, people use Winstrol to lose fat and increase the number of red blood cells in their body. These RBCs bring more oxygen, which makes your energy levels higher.

Winstrol is a steroid that you do not inject into your muscles or veins. You take it by mouth, which is less painful than the other option.

Also, taking it by mouth lets you control how much you take. Injecting it can be risky because you might take too little or too much.

Also Read: Steroids for Sale Black Friday Deals and Savings Offer 2022: Buy Steroids Online

Is Winstrol Legal?

Lawyers watch Winstrol steroid closely. The US says it is a controlled substance, but allows it to be sold in a black market.

This might be done to warn people who want to buy Winstrol to check its ingredients, effects, and their own health before buying it.

In many countries, it is popular among bodybuilders and you can buy and sell it.

Thats where Wincut can help you.

It helps with fat loss without having to use an extreme and dangerous diet.

It also helps you keep your energy levels high, so you can work harder and longer in the gym.

Heres why we think its a great option for any cutting or finishing cycle.

Removes the extra fat

Did you know that our metabolism always changes to the amount of calories we eat?

This is why extreme diets dont work. Your body will eventually change and slow down your metabolism to stop you from losing more fat.

When you have used dieting to reach a certain level of body fat, Wincut helps you go past that limit by helping your body get rid of the extra fat.

It helps to restart your metabolism and make your bodys fat burning ability higher. This means that you can finally get that ripped, veiny look youve been working for.

Get clear, pumped abs

Abs are made in the kitchen, they say. Thats not wrong. But what if you want to get really lean and ripped abs?

While diet is important, Wincut can help you go one step more by helping your muscles to get pumped.

You see, sometimes a good pump can make your muscle visibility much better. Thats where Wincut comes in.

It helps you get that pumped look with more stamina and longer pumps. This leads to more clear, ripped abs.

No more water weight

Even when you lower your body fat levels to the single digits, you might still see that your muscles look a bit swollen and soft. Thats because of water weight.

Wincut helps you get rid of that extra water weight and make your muscles look even more sharp.

That too, without changing your electrolyte levels. Unlike Winstrol, you do not get any cramps with Wincut. You look your best and also work at your best.

Wincut vs. Winstrol Cost

Wincut costs $58.99 for a bottle of 60 pills. This is about $1 per day, which is very cheap for an effective supplement that can help you cut and finish like Wincut.

On the other hand, Winstrol costs around $100 per month depending on where you buy it from. Plus, most of it is fake anyway.

Effects of Winstrol After Two Weeks

Winstrol works very differently from testosterone in your body.

Testosterone makes your body hold a lot of water. But Winstrol does the opposite, and makes it very dry, which creates a special artistic look.

Every muscle stands out, as if they were not made by exercising in a gym. But rather by a painter.

A thin layer of skin covers them, which makes your body look beautiful. These effects appear within two weeks of using Winstrol. But the experts in bodybuilding suggest a maximum of 6 to 8 weeks for a cycle.

How Fast Does Winstrol Work?

To enjoy the benefits of Winstrol, you need to be ready for it. Get fit and lower your body fat to a single number.

Winstrol is fast, but not magic. So, you have to work hard to get to a starting point and then use Winstrol to enhance its effects.

If you follow a good routine, Winstrol can make a quick cutting effect, giving you dry muscles!

How Much Winstrol Do I Need for A Cycle?

For this, you have to decide your goals first. That is, if you are using Winstrol for losing fat, gaining muscle or increasing strength.

If it is for losing fat, you can use about 25 to 50 mg per day. If it is for gaining muscle, then the dose can be from 80 to 100 mg.

To boost your strength levels, you can think of a dose of around 75 mg every day.

Winstrol Cycle Before and After

The most common use of the steroid is to lower body fat and increase muscle gains. The steroid starts working in two weeks.

Then, the user sees changes in muscle shape and size.

These changes make the fat percentage lower and the body more muscular.

After the cycle ends, the user feels more energetic, which makes their workouts harder. As a result, muscle mass grows faster, and the metabolism works better.

In other words, the before and after of the cycle would be dramatically different if done in accordance with what the experts suggest.

The user must be acutely aware of its own health. This is because Winstrol usage may aggravate underlying health problems and cause permanent damage to the organs. It may also trigger insomnia and high cholesterol.

What Does Winstrol Do to Your Body?

Winstrol is popular among bodybuilders because it makes you lose fat, grow muscle, and bulk up your body in different ways.

What it does inside is tell your muscles to make more proteins. This makes your muscles bigger.

Since protein speeds up your metabolism and your muscles need room to grow, it also lowers your fat level.

Protein has a big role in making your muscles bigger and burning fat in your body. But it also helps your muscle health and power.

The increase in protein goes along with the production of ATP, which is Adenosine Triphosphate. It is a molecule in your body that is responsible for moving energy throughout your body and involving every cell.

What Can I Expect from the Winstrol Cycle?

What you expect from the Winstrol cycle depends on what you want from it.

Winstrol increases your metabolism and energy levels in your body. If you use these well, you may get closer to your goals of bulking or cutting.

But the steroid also has a downside that you need to pay attention to. This includes the chance of Winstrol side effects such as joint pain, high cholesterol, and sleep problems.

If you have cholesterol issues or joint problems already, the negative results would be more than the positive ones.

You should be realistic in your expectations. Only if you know the pros and cons well enough should you go ahead with Winstrol.

Legal Winstrol for Sale: How to Buy Winsol?

Originally posted here:
12 Week Testosterone and Winstrol Cycle - What is Winstrol Used For - Deccan Herald

In recent years, testosterone replacement therapy (TRT) has been considered a potential treatment for hypogonadism, a condition characterized by low production of the male hormone testosterone. Some studies suggested that TRT could possibly slow the progression of prediabetes or diabetes. However, recent research contradicts these assumptions, finding no evidence that TRT benefits metabolic health in men with hypogonadism.

Published in JAMA Internal Medicine, the study evaluated whether TRT could prevent progression from prediabetes to diabetes or improve glycemic control among those already diagnosed with diabetes. The study involved 5204 participants with hypogonadism across 316 trial sites. The results were clear: there was no difference in the progression to diabetes between the testosterone and placebo groups. Furthermore, there were no differences in glycemic improvement among men with diabetes.

Another significant study, the TRAVERSE Diabetes Study, produced similar findings. The study showed that TRT for men with hypogonadism and prediabetes is not associated with a significantly lower rate of progression to diabetes. The research found no significant differences in terms of glycemic remission and the changes in glucose and A1c levels between the testosterone- and placebo-treated men with prediabetes or diabetes.

The findings of the TRAVERSE randomized trial suggest that TRT alone should not be used as a therapeutic intervention to prevent or treat diabetes in men with hypogonadism. These findings could be pivotal in weighing the potential benefits of TRT in middle-aged and older men with hypogonadism who have prediabetes or diabetes.

A substudy of the TRAVERSE trial found that TRT does not increase the risk for cardiovascular events, fracture, or prostate cancer, and may only improve anemia, but not cognitive function. According to the research, the only indication for TRT in men with hypogonadism remains treatment of bothersome symptoms of hypogonadism, generally sexual dysfunction.

In conclusion, these studies highlight the importance of careful consideration before prescribing TRT for the management of prediabetes or diabetes in men with hypogonadism. The findings suggest that TRT does not slow the progression of these conditions, nor does it significantly improve glycemic control. Therefore, it is crucial for healthcare professionals to make informed decisions based on the latest research when considering different treatment options.

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Testosterone Replacement Therapy (TRT) and Diabetes: What Recent Research Reveals - Medriva

Shalender Bhasin, MBBS

Credit: UKMC

A substudy of the TRAVERSE trial revealed the progression from prediabetes to diabetes did not significantly differ between testosterone replacement therapy (TRT) or placebo treatment among middle-aged and older men with hypogonadism.1

The nested TRAVERSE Diabetes Study, an intention-to-treat analysis within the placebo-controlled randomized clinical trial, was conducted at 316 trial sites in the United States. Among the more than 5200 randomized participants, TRT did not improve glycemic control in those with hypogonadism and prediabetes or diabetes.

The findings of this study suggest that TRT alone should not be used as a therapeutic intervention to prevent or treat diabetes in men with hypogonadism, wrote the investigative team led by Shalender Bhasin, MBBS, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Womens Hospital, Harvard Medical School.

Evidence has linked low testosterone to an increased risk of prediabetes and type 2 diabetes (T2D) in men.2 Men with prediabetes and diabetes have a high prevalence of hypogonadism, while a substantial portion of individuals receiving TRT have diabetes or prediabetes.3 TRT in men with hypogonadism can reduce whole-body and visceral fat mass, increase muscle mass, and improve insulin sensitivity.

As it is not well-understood, Bhasin and colleagues suggested further knowledge on testosterones efficacy in preventing progression from prediabetes to diabetes or in inducing glycemic control would be beneficial for clinicians, as well as patients weighing the benefit-risk profile of TRT.1

Men aged 45 to 80 years with hypogonadism and prediabetes, or diabetes were enrolled in TRAVERSE between May 2018 and January 2023. Participants were randomized 1:1 to receive 1.62% testosterone gel or placebo gel until the end of the study. All participants, the study staff, and those assessing outcomes were blinded to randomization.

The primary endpoint of the TRAVERSE Diabetes Study was the risk of progression from prediabetes to diabetes, assessed at all post-randomization time points using repeated-measures log-binomial regression. Secondary endpoints consisted of the risk of glycemic remission in those with diabetes at baseline, defined as a hemoglobin A1c level of 6.5% or two fasting glucose measurements <126 mg/dL without antidiabetic medication use.

Of the 5246 individuals randomized in TRAVERSE, 5204 were included in the analysis set for the nested substudy. Among this population, 1175 had prediabetes (607 randomized to TRT), and 3880 had diabetes (1917 randomized to TRT). Baseline characteristics were similar between the testosterone- and placebo-treated cohorts with prediabetes or diabetes the mean age was 63.8 years, and the mean HbA1c level was 5.8%.

Upon analysis, investigators found the relative risk of progression from prediabetes to diabetes did not significantly between testosterone and placebo groups. Progression risk was identified in 4 of 598 (0.7%) vs. 8 of 562 (1.4%) at six months, 45 of 575 (7.8%) vs. 57 of 533 (10.7%) at 12 months, 50 of 494 (10.1%) vs. 67 of 460 (14.6%) at 24 months, 46 of 359 (12.8%) vs. 52 of 330 (15.8%) at 36 months, and 22 of 164 (13.4%) vs. 19 of 121 (15.7%) at 48 months (omnibus test, P = .49).

Further results showed the risk of glycemic remission among those with diabetes at baseline did not significantly differ between the testosterone and placebo groups. Changes from baseline in fasting glucose or HbA1c concentrations were also similar among testosterone- and placebo-treated groups in those with either prediabetes or diabetes at baseline. Post-hoc sensitivity analysis of the primary and secondary events occurring within 30 days or 365 days after stopping treatment exhibited similar results to the primary analyses.

Based on these data, Bhasin and colleagues indicated the study results do not support the use of TRT alone in the prevention or treatment of diabetes in men with hypogonadism. Still, they could help weigh its benefit-risk profile for each individual.

The trials findings may be useful in weighing the potential benefits of TRT in middle-aged and older men with hypogonadism who have prediabetes or diabetes, investigators wrote.

References

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Testosterone Ineffective in Preventing Diabetes in Men with Hypogonadism - MD Magazine

Testosterone replacement therapy (TRT) is a commonly sought treatment for men suffering from hypogonadism, a condition characterized by low levels of testosterone. While TRT has been linked to various benefits including increased sex drive, improved bone density and muscle mass, and alleviation of hypogonadism symptoms, recent studies challenge the belief that TRT can play a role in preventing the progression of prediabetes or diabetes in these men.

The TRAVERSE Diabetes Study, a comprehensive research endeavor involving 5204 participants across 316 trial sites, has provided crucial insights into the effectiveness of TRT for metabolic health. The primary aim of the study was to explore whether TRT could halt the progression from prediabetes to diabetes or enhance glycemic control among those already diagnosed with diabetes.

Contrary to previous evidence, the study found that TRT did not significantly affect the risk for progression to diabetes, glycemic remission, or changes in glucose and A1c levels. Furthermore, the progression to diabetes did not differ between groups, and no significant differences were observed in glycemic improvement among men with diabetes.

This indicates that while TRT may be beneficial in treating the symptoms of hypogonadism and improving overall quality of life, it does not appear to have metabolic benefits. As such, the authors of the study concluded that TRT should not be used as a singular therapeutic intervention to prevent or treat diabetes in men with hypogonadism.

Interestingly, the study also highlighted the high rates of testosterone use, even in the absence of proven metabolic benefits. This suggests that men and healthcare providers may need to reassess the use of TRT, particularly if the primary goal is to prevent or manage diabetes. Moreover, it underscores the importance of holistic treatment plans that encompass lifestyle changes and other medical interventions.

While TRT may not be effective in preventing diabetes progression, it is important to note its role in managing male fertility in hypogonadal patients. Testosterone plays a key role in regulating body functions in men. However, traditional TRT can have negative effects on male fertility. Recent advances in research have shed light on new methods of administration and the usage of ancillary medications to maintain fertility in hypogonadal patients.

TRT can be administered in various forms such as gel, injections, patches, buccal patches, capsules, nasal gel, and pellets. Each type has its own set of advantages and disadvantages, and the choice of administration should be tailored to the individuals needs and lifestyle. As with any medical intervention, the potential benefits and risks must be weighed carefully.

In conclusion, while TRT can help manage symptoms and improve the quality of life for men with hypogonadism, it does not show any significant benefit in slowing the progression of prediabetes or diabetes. It is essential for healthcare providers to convey this to patients and to develop comprehensive treatment plans that address the patients overall health and wellbeing.

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Testosterone Replacement Therapy (TRT) and Diabetes: What You Need to Know - Medriva

Menopause is something we usually associate with women and is a condition that marks the end of the female menstrual cycle. However, male menopause, or andropause, is a condition that involves aging-related hormone changes in men, according to the Mayo Clinic. The new phenomenon sees testosterone levels gradually decrease by one percent every year once a man reaches the age of 40. The symptoms are similar to those experienced by women during menopause, like, reduced libido, fatigue and decreased muscle mass. There are solutions to mitigate the decline in testosterone levels like injections, oral medication, creams and over-the-skin patches. Natural solutions to maintain testosterone levels include certain lifestyle changes like regular exercise, healthy eating and adequate sleep. Research in Obesity Reviews shows that obesity can lead to lower testosterone levels, with weight loss being another to manage symptoms.

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Understanding Andropause: Men's Answer To Menopause | Lifestyle | theweeklyjournal.com - The Weekly Journal

If you want to gain a good picture of a man's overall health, measure his testosterone levels. Testosterone isn't just important for libido, strength, and energy it also plays a role in bone health, cardiovascular health, and the immune system. And increasingly, research suggests the hormone is a reliable indicator for disease and longevity.

Researchers have found that men with low testosterone are more likely to suffer from a number of ailments, from heart attacks to diabetes and they may not live as long.

Theres a clear association between testosterone and mortality, says Hugh Jones, an endocrinologist for the Barnsley Hospital NHS Foundation Trust and a professor at the University of Sheffield in England.

So what does this mean for the roughly quarter of men over 40 who have low testosterone? And is it possible to ward off some of the negative health effects associated with low T?

In 2022, scientists at Baylor University and the University of Texas at San Antonio took a deep dive into the relationship between testosterone and early death. Pulling up records for 10,225 patients who had participated in the National Health and Nutrition Examination survey between 1999 and 2004, the researchers found that the lower a mans testosterone levels, the more likely he was to die of disease before 2019. That likelihood was especially high for heart disease, but lower testosterone was also associated with a higher chance of dying from respiratory disease and Alzheimers.

Previous research supports these findings. A 2021 study published in the journal European Urology Open Science found that among 1,792 men who filled out a national survey between 1999 and 2014, those with low testosterone were more than twice as likely to be dead by 2015 compared to men with higher testosterone levels. They were also more likely to have BMIs in the obese category, diabetes, high blood pressure, and risk factors for heart disease.

So do these studies mean that low testosterone causes disease and early death?

Yes and no, Jones says. In his own research, hes found that low testosterone does seem to worsen mens health. In one study, Jones and his colleagues looked at almost 1,000 men with coronary artery disease, in which arteries that supply blood to the heart become dangerously narrow. They compared this population to men who did not have heart disease and found that the men with coronary artery disease had lower overall testosterone.

Additionally, low testosterone was one of the most reliable predictors of death in both groups, surpassed only by weakening of the heart muscle tissue. Men with low T were more than twice as likely to die due to a cardiovascular problem compared to men with normal testosterone levels.

These same scientists then followed 500 patients with diabetes over a period of six years. They found that by the end of the study, 17.2% of patients with low testosterone levels had died, compared to 9% of patients with testosterone in the normal range.

In a different study, Hugh and his colleagues were able to partially reverse the relationship between low T and higher mortality risk from diabetes in a subset of men who received testosterone replacement therapy. In that population, 8.6% of patients died by the end of the study compared to 19.2% who did not receive treatment.

It may be that low testosterone does put you in a position where you have health consequences, Jones says. However, the relationship is likely more complicated than that, he adds. In many cases, disease can actually be what causes low T, which could drive the link between low T and death in many cases.

Disease likely lowers testosterone as the body diverts resources away from the reproductive system towards keeping the body healthy. In addition, major causes of death, such as heart disease and diabetes, are often associated with higher body weight, which may exert its own dampening effect on testosterone because fat cells convert testosterone into estrogen. That can create a negative feedback loop, Jones says: If you have a disease, it may lower your testosterone, which may make that disease worse.

So why does low testosterone worsen disease? The answer to this question is murky, but scientists have a few ideas.

One of them has to do with inflammation, the bodys response to acute illness or injury, in which the immune system releases chemicals and blood cells to fight foreign invaders and heal itself. In the short term, inflammation is a good thing, but chronic inflammation puts stress on the body, making it more susceptible to conditions like heart disease and diabetes.

Testosterone is what scientists call an immune modulator, Jones says after inflammation is no longer needed, it reduces the number of inflammatory proteins called cytokines in the body. So low T could mean the body is worse at tamping down inflammation.

Another possible explanation: In animal studies, testosterone seems to impact the way the body stores fat, Jones says. Rodents with normal testosterone tend to store fat under the skin, whereas those with lower testosterone tend to store more fat around their organs and within the walls of their arteries. In humans, fat stored in these areas is a major predictor of deadly conditions like heart disease.

If you do have low testosterone or suspect that to be the case, you dont need to panic, says Michael Muehlenbein, Ph.D., a biological anthropologist studying evolutionary endocrinology at Baylor University.

Low testosterone may be a predictor of mortality in some cases, he says, but the relationship is not necessarily causal.

Besides, what constitutes low testosterone is a controversial question, and many men who have testosterone levels below the normal range remain healthy.

Still, its a good idea to get your levels checked out if youre experiencing symptoms such as erectile dysfunction, reduced libido, or fatigue. And if you do have low low testosterone, it may be worth talking to your doctors if it could be the result of another condition. That may then inform whether you should start testosterone replacement therapy.

The trick will be determining if low T is a cause of a disease which would then potentially warrant hormone adjustment or is a consequence of having the disease, Muehlenbein says.

Link:
Low Testosterone May Lead To Early Death. Here's What That Means For You - Fatherly

Search results

The search strategy identified 214 studies and 6 additional papers were identified through other sources for a total of 220 studies. After removing the duplicates, 184 studies were screened of which 152 were excluded based on title and abstract. Full text of the 32 selected studies was obtained. 14 studies were excluded: 4 studies were conducted on animal models, 10 didnt evaluate TT and LH levels. The PRISMA flow diagram is presented in Fig.1. Complessively, 18 records fulfilled the inclusion criteria and were included in the final analysis14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31.

PRISMA flow diagram. TT: Testosterone; LH: Luteinizing Hormone.

Eighteen studies met the inclusion criteria and were included in this analysis, overall 1,575 male patients with Covid-19 infection and 886 male controls. According to the severity of the disease, 823 patients were classified as presenting moderate disease and 500 as having severe disease. Patients enrollment ranged between 2020 and 2022. 15 studies14,17,18,19,20,21,22,24,25,26,27,28,29,30,31 exhibited a prospective cohort design and 3 studies reported a retrospective cohort design15,16,23. The studies included were conducted in Turkey14,17,21,22,25,29 Italy15,16,26,27,28 China24,30,31 USA18, Greece20, Russia19, Austria23. Among the studies included, 11 were controlled16,17,19,20,21,24,25,28,29,30. Collected data included testosterone levels 14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31, LH levels14,17,19,22,23,24,28,29,30, IL-6 levels15,23,26,27,28,30,31, lymphocytes count14,15,16,23,24,26,27,28,30,31, D-dimer levels14,15,16,20,24,26,27,31. The characteristics of the 18 studies included are presented in Table1.

Out of n=1814,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31 studies encompassed in the systematic review, n=1016,17,19,21,22,24,25,28,29,30 were further meta-analytically compared with regards to mean TT levels variations between Covid-19 and control populations. Of note, at this preliminary assessment, there was considerable heterogeneity across each single study with I2 98.45%, Q (9): 580.22, p<0.00. Publication bias was initially assessed by Galbright and Funnel plot (Suppl. Fig. 1). Inspection of both plots suggested that there was no small-study effect with the smaller studies tending to have higher SMD variability, suggesting absence of publication bias (Egger test, p=0.96). Additionally, the Trim and Fill method suggested that no studies would have needed to be included to remove residual asymmetry from the funnel plot. The main contribution to study heterogeneity was indeed identified by sub-group analysis summarized in Suppl. Fig. 2. Interestingly, year of publication which in this case is directly associated with the progression of the Covid-19 pandemic exhibited a significant ascending influence on SMD observed, while no further study design nor cumulative sample size of patients accrued was associated with the observed heterogeneity. The effect of publication year was further highlighted at cumulative meta-analysis sorted by year, where increasing variations in SMD of TT levels across the studies were observed (Suppl. Fig. 2). However, as per sensitivity analysis, the leave-one-out analysis suggested acceptable variation along the cumulative SMD observed when clustering the data by publication year. According to predefined random-effects model, we found a significant reduction in the SMD of testosterone levels in Covid-19 patients compared to controls (3.25, 95%CI 5.93, 0.57, p=0.00, I2=98.45%). The difference was even higher when examining men with severe Covid-19 (5.04, 95%CI 8.82, 1.26, p=0.00, I2=96.60%) (Fig.2).

Forest plot for Standardized Mean Difference (SMD) across studies presenting serum Total Testosterone (TT) in Covid-19 male patients vs. male control (A), clinically severe Covid-19 patients vs. control (B), clinically severe Covid-19 vs. clinically moderate Covid-19 patients (C) and, Covid-19 related deaths vs. Covid-19 survivor patients (D).

Additionally, within the Covid-19 population, we assessed patients stratified by severity of clinical manifestations. As further evidence, compared with patients exhibiting moderate Covid-19 symptoms, patients with more severe sequelae exhibited lower levels of testosterone showing a slight yet significant absolute higher SMD (3.53nmol/L, 95%CI 5.11, 1.95, p=0.00, I2=88.19%).

This was corroborated across the n=314,15,18 experiences which reported outcomes stratified according Covid-19 survivors and non-survivors, confirming a similar overall decrease in SMD serum TT levels (3.04, 95%CI 4.05, 2.04, p=0.42, I2=0.00%) (Fig.2).

Finally, in order to explore the remaining heterogeneity observed, we investigated the role of patient available comorbidities or inflammatory/haemato-chemical variables retrieved to the SMD estimates by meta-regression analysis. As expected, there was a direct correlation between increasing BMI of the Covid-19 population and the SMD observed across the studies (Coeff. 2.48, SE: 1.15; p=0.033; Suppl. Fig. 3). Moreover, the sole haemato-chemical confounder significantly associated with TT variation was the absolute lymphocyte count depicting an inverse trajectory with the SMD observed across the studies (Coeff. 7.37, SE: 2.19; p=0.001; Suppl. Fig. 3).

Regarding LH levels, only n=717,19,22,24,28,29,30 studies reported the needed information to further compare the overall populations and the sub-groups assessing the outcomes according to the severity of Covid-19 clinical manifestations. A considerable heterogeneity was documented also in this setting with I2 95.60%, Q(6): 136.32, p<0.02. Additionally, the inspection of both Galbright and Funnel plots suggested that there was a significant small-study effect with the smaller studies tending to have higher SMD variability, suggesting the existence of higher risk of bias among the publications assessed (Egger test, p=0.035). However, the Trim and Fill method suggested that only n=1 study would have needed to be included to remove residual asymmetry from the Funnel plot (Suppl. Fig. 4). This preliminary finding was further confirmed at sub-group analysis where the size of the sample analysed was significantly associated with greater variability in the pooled SMD yet not being influenced by the publication year like previously observed (Suppl. Fig.4).

In contrast to TT levels, the effect on cumulative LH variations was non-significant nor clinically relevant between Covid-19 cases and matched controls (SMD: 0.69, 95%CI 0.56, 1.94, p=0.00, I2=95.60%) ranging along the null-effect line from 3.55, 95%CI 2.64, 4.46, to 2.53, 95%CI 4.73, 0.33 in the study of Cinislioglu et al.17 and Xu et al.30 respectively. This was also true when comparing controls with the n=317,28,30 studies with more severe Covid-19 population (SMD: 0.41, 95%CI 2.37, 3.19, p=0.00, I2=95.54%) (Fig.3).

Forest plot for Standardized Mean Difference (SMD) across studies presenting serum Luteinizing Hormone (LH) levels in the Covid-19 patients vs. control (A), clinically severe Covid-19 patients vs. control (B), and clinically severe Covid-19 vs. clinically moderate Covid-19 patients (C).

Furthermore, at sensitivity analysis through leave-one-out assessment there was no single study effect size which would have significantly impaired the observed pooled results if omitted from the analysis (Suppl. Fig. 5).

At meta-regression on quantitative variables available, the relative percentage of Covid-19 patients with active smoking status was the sole factor influencing the pooled SMD estimate for serum LH levels (Coeff. 0.08, SE: 0.01; p=0.001; Suppl. Fig. 6).

Finally, when sub-analyzing within the Covid-19 severity of clinical manifestations, there was no significant or clinically relevant SMD across the n=5 studies included14,17,26,28,30 0.28 (95%CI 1.55, 1.00, p=0.00, I2=88.52%).

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Systematic review and meta-analysis of serum total testosterone and luteinizing hormone variations across ... - Nature.com

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