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Oct 9

Covid-19 could lower testosterone levels and libido in men – heres what the new study found – Morpeth Herald

A new study has revealed that men who contracted Covid-19 have their testosterone levels lowered by 30 per cent, on average.

Even two thirds of men who showed no symptoms reported a loss of libido.

Researchers in Turkey analysed levels of sex hormone in 232 men who were hospitalised after they tested positive for Covid-19.

What is hypogonadism?

More than half (51 per cent) of the men had developed a condition called hypogonadism, meaning their bodies did not produce enough testosterone.

On average participants levels were drained by 30 per cent post-infection, to borderline unhealthy levels.

Academics from the University of Mersin who ran the study claim there is a direct correlation between severe illness and lower testosterone levels.

Lead author, Professor Selahittin ayan (a urologist at the university) said, In our study, the mean total testosterone decreased, as the severity of the Covid-19 increased.

The mean total testosterone level was significantly lower in the ICU group than in the asymptomatic group.

In addition, the mean total testosterone level was significantly lower in the ICU group than in the standard care group.

Why do men need testosterone?

Testosterone is key to the development of sex organs and muscle growth. The hormone also helps regulate the bodys immune responses, including fighting off viral infections.

Low levels have been linked to an increased risk of dying from the flu, as well as inflammation, heart disease and high blood pressure.

A healthy level of testosterone is usually considered to be above 300 nanograms per decilitre (ng/dl).

Results in the study showed that patients saw their levels drop by a third, on average, from 458 ng/dl to 315 ng/dl.

Professor ayan describes the uses of the hormone saying, Testosterone is associated with the immune system of respiratory organs, and low levels of testosterone might increase the risk of respiratory infections.

Low testosterone is also associated with infection-related hospitalisation and all-cause mortality in male in ICU patients, so testosterone treatment may also have benefits beyond improving outcomes for Covid-19.

Read the original:
Covid-19 could lower testosterone levels and libido in men - heres what the new study found - Morpeth Herald


Oct 8

Sexy but unreliable: why women should beware men with deep voices – The Guardian

Name: Deep-voiced men.

Age: 18 and up.

Appearance: Inherently untrustworthy.

Why are deep-voiced men untrustworthy? Because they are going to cheat on you, honey.

This seems like a horrible generalisation. Yes, but it is a generalisation backed up by science, so it counts.

Really? A study conducted by Southwest University in China proved it. Several heterosexual, non-smoking men were asked to read a list of words. These words were analysed for frequency and pitch.

And? Then the men were asked to take a psychological test to determine their attitudes to infidelity and relationships. And guess what?

What? The men with deeper voices were found to be less committed to romantic relationships and more likely to cheat.

How terrible. Apparently, it has to do with testosterone levels. Generally speaking, men with lower voices have more testosterone than men with squeakier voices. The researchers said: Testosterone and the characteristics dependent on testosterone can be reliable indicators of quality-dependent conditions or behaviours.

What does that mean? It means men with deep voices are all scoundrels.

But deep voices are so sexy. See? You are part of the problem. Women find men with deep voices sexy, because deep voices are associated with high testosterone, which suggests the men will produce healthy children.

Right. But this means that, if you are a deep-voiced man, women are throwing themselves at you all the time because they want some of those healthy babies. And if women are throwing themselves at you around the clock, you are eventually going to cave in to temptation.

Wow. Are you really blaming women for men being unfaithful? No, I hate deep-voiced men as much as the next guy.

Oh dear. Do you have a squeaky voice? Just because I dont sound like Barry White with laryngitis, it doesnt mean my voice is squeaky. In fact, it means I am actually a pretty good catch.

Because you sound like Alvin and the Chipmunks when you talk? Exactly. Although you might initially mistake my voice for an unoiled catflap, Im biologically preordained to remain faithful.

Surely the human race has evolved beyond such superficial pitfalls. Oh, you think a woman would prefer a man who cooks dinner, changes nappies and shares the emotional labour of a household?

Yes. They might. But, evolutionarily speaking, they would much prefer it if a man did all that while not sounding like a hapless bystander at a helium-factory explosion.

Do say: Men with deep voices are more likely to cheat.

Dont say: Ladies, your new dream man is Mickey Mouse.

Read the original:
Sexy but unreliable: why women should beware men with deep voices - The Guardian


Oct 8

13 Foods That Kill Testosterone – The Good Men Project

We all have a good high-level understanding of what eating habits to keep and what lifestyle to follow to maintain a healthy body and keep testosterone high.

But are you also aware of the foods that kill testosterone or might lower T-levels in your body?

Some of these foods do have other desired nutrients which the body needs for healthy functioning. But they can also be counterproductive from a testosterone perspective.

Testosterone is one of the major sex hormones in the body. Although men produce more testosterone, it is an important hormone for women as well.

Here is the list of the testosterone killing foods :

A study published inGerman Medical Journal, points that soy are structurally and functionally analogous to the estrogens. But concludes that more research is needed to make a final verdict.

However, another related study showed that breast tenderness and estrogen concentrations returned to normal after a man stopped using soy.

Phytoestrogens, which are abundantly found in soy may affect the bodys testosterone level by increasing the estrogen in the male body.However, a deep study is still required to take the final call.

Also called Edamame, these are most commonly used as ingredients in a variety of regular food we eat.

High levels of soy in a womans body can decrease sex hormones and disrupther ovarian function,said a study in the Journal of Nutrition. It eas noted that about half a serving of soy per day was enough to slash sperm count by 40 percent in healthy males, the Harvard School of Public Health found.

Dietary Estrogen which is the dominant female sex hormone is abundantly found in dairy and other related products.

Studies have shown that men who consume more milk and dairy products have higher levels of estradiol which is another female hormone. This can lower the bodys production of testosterone the primary male sex hormone with the effect of raising voice pitches, increasing male breasts and erectile dysfunction.

Over 80 percent of commercial milk originates from pregnant cows: a time when their estrogen levels are markedly high. With years of genetic tampering, cows and buffaloes now give milk throughout their pregnancy, which only does more harm then good.

Alcohol negatively impacts every aspect of the body including hormones.

The three glands that produce testosterone are :

Alcohol can disrupt testosterone production by interfering with all three glands.

Mint is very popular as a soothing tea and refreshing evening drink with plethora of recipies that mention it as a vital ingredient.

However, a review posted to BMC Complementary & Alternative Medicinenoted that there is some high-quality evidence showing that mint lowers testosterone levels in women with PCOS.

However, there is not enough high-quality evidence surrounding the effect of the herb in general or specifically to males and their testosterone levels.

This one is most widely understood towards killing testosterone level. All the processed food contains Trans fats which has been directly linked to anincreased risk of heart disease, type 2 diabetes and inflammation.

Additionally, some studies have found that regularly consuming trans fats from sources like processed foods could decrease testosterone levels.

For example, one study in 209 men showed that those who consumed the highest amounts of trans fats had 15% lower levels of testosterone than those with the lowest intake.

Extracts of licorice root are widely used in many countries as flavoring agents, breath fresheners, or candy. The active component of licorice is glycyrrhizic acid, which is hydrolyzed in vivo to glycyrrhetinic acid.

Glycyrrhizic acid interrupts the conversion of a testosterone precursor into the male hormone.

A key differentiation is to understand that this applies to licorice root rather than licorice candy, which often doesnt contain any licorice root.

Flaxseeds are the in thing nowadays where every dietary expert from amateur to professional is sprinkling flaxseeds on almost all their meals.

Even though they are rich in Omega-3 fatty acids, there has been a link with flaxseedscontributing to killing testosterone.

Butmore large-scale studies are needed to further evaluate the effects of flaxseed on testosterone levels.

As per thepesticide data program, a human body is exposed to a dozen different varieties of pesticides through food and packaging. Most of these are endocrine disruptors, meaning they impact our male.female hormones.

One of the most estrogenic is 4-hexyl resorcinol, which is applied to shrimp to prevent them from discoloration. Other seafood with high pesticide loads: tilapia, eel, and farmed salmon.

Sugar is everywhere and bound to enter your system even if you are not adding spoon full in your tea or coffee.

Researchers from Massachusetts General Hospitalhave found that glucose ingestion was associated with a significant decrease in the male hormone testosterone.

The study, published in the journal Clinical Endocrinology, shows that 75g of sugar intake causes a 25 per cent drop in testosterone levels for up to two hours after consumption.

Making an effort to mindful stay away from sugar could be just what doctors will prescribe for your testosterone.

Canned food is notoriously high in sodium and can lead to erratic blood pressure. Additionally, it also affects the normal blood flow to various body parts, including genitals.

Stick with fresh food which is home cooked and mindfully garnished.

The main culprit here is Bisphenol A, commonly referred to as BPA which is a chemical component found in most plastic food containers and cans.

A study in the journalFertility & Sterilityfound a direct relation between urinary BPA concentration in men and lower total sperm count, concentration and vitality.

Women with the highest BPA levels in the body saw a reduction in the number of eggs that matured, according to a study out of Harvard School of Public Health.

Honestly, beets are one of the best food out there which are just loaded with nutrients.

However, like any root food, it also contains estrogen enhancing compounds which can cause further testosterone depletion if there is already a depletion.

So choose your quantity wisely.

It has been reported several times that having coffee can lead to anxiety in individuals causing them to feel jittery. This not being a common occurrence, but it has led to erratic libido patterns in males.

So know your body and choose coffee wisely.

Certain medications like Antidepressants and Adderall can interrupt how your body produces and manages hormones like serotonin, epinephrine, and dopamine, which all influence your sex drive.

As such medications are vital to treating individuals, make sure you are consuming just the right dosage and not going overboard.

Also, speak to your physician and explorealternatives like mulitmodal therapies and life style changes that can decrease the reliance on these testosterone killing influencers.

Previously Published on Dad Tribe

Shutterstock

See the original post here:
13 Foods That Kill Testosterone - The Good Men Project


Oct 8

Erectile Dysfunction: A Look at the Most Common Causes – Feed Leader

Erectile dysfunctions are more common than most men believe, and while they can always leave someone in an embarrassing position at an awkward time, the reasons can be benign as well. Unfortunately, not every case of unexpected ED is harmless or temporary. As we look through the common reasons behind erectile dysfunctions, it will uncover both relatively harmless, as well as a few potentially fatal conditions that can be responsible for impotence in men.

The primary action behind impotence can be identified as a lack of blood supply to the penis, which is universal in nature. The causes that can be responsible for the lack of sufficient blood supply are plenty, but the action is always the same, irrespective of the reason. This is directly related to conditions of the heart and the arteries, as it is the heart that pumps blood through arteries and sends them to the extremities via veins and blood vessels.

As a result, any heart condition or vascular condition that can constrict or slow down the flow of blood could at times be responsible for impotence. Common cardiac and arterial health issues that have been proven to cause erectile dysfunction are as follows:

As we age, we lose muscle mass and sexual potency, but the rate of loss is not equal or even similar in all men. Aside from genetics, there are also additional factors that contribute to lowered testosterone in men as young as 30. To know whether or not lowered testosterone levels are responsible for your ED, check the low T symptoms identified by Manual. If you can relate to the symptoms, then rest assured that low T is not just one of the most common causes of impotence, but it is also very treatable with appropriate steps and meds.

Consult with experts to know what sildenafil can do for you and how it should be administered to help you overcome your ED, alongside all the other associated symptoms. Testosterone is the prime male hormone, and in order for a mans body and mind to function in the way that it should, there needs to be a sufficient natural production of it. In case that cannot be achieved, external testosterone therapy might be essential for preventing impotence, hair fall, depression and several other similar symptoms.

Diabetes is a direct and acute cause for erectile dysfunction and that applies to men with both Type I and Type II diabetes. However, men suffering from Type II diabetes experience ED far more often than men with Type I diabetes. Potentially, the damage can be permanent for men with diabetes if they do not act in time to control the disease itself.

Unlike most of the other causes mentioned so far, diabetic men who did not or could not treat their condition from an early stage are likely to experience permanent nerve and blood vessel damage, leading to perpetual impotence. On the other hand, if their blood sugar is kept under control from an early stage with changes in lifestyle and medication, it is possible for men with diabetes to lead a healthy and sexually satisfying life. If you are experiencing frequent episodes of ED, it is probably a good idea to get checked for diabetes. The urgency of the situation will gain more severity in case the patient also has one or more diabetic parent/parents.

Depression is often defined as a purely psychological cause for erectile dysfunction, but it is medically incorrect to use the classification universally. Temporary depression from a genuine cause such as the death of a close family member is mostly psychological in nature. In most cases, men get over temporary and acute depression on their own, or perhaps just by talking about the cause with someone close, or even a professional. However, the same cannot be said about clinical depression, where the brain becomes incapable of producing sufficient levels of dopamine and serotonin.

Unfortunately for those suffering from clinical depression, antidepressants are often found to be directly responsible for causing impotence in men. Since this is a unique scenario where both the disease and the cure can individually and simultaneously cause erectile dysfunctions, its a very tricky situation to deal with. If clinical depression is indeed affecting you and you have been prescribed antidepressants for managing the chemical imbalance, countering the entire scenario would require a combined effort from you, your psychiatrist and your partner. The idea should be to find alternatives to SSRIs and use break periods to help lessen the pharmaceutical and psychophysical causes of impotence as best as possible.

There are two different types of stress, although they often fuel each other, making it difficult to separate one from the other. Physical stress is a result of strenuous physical activities and mental stress is a result of worry, mental trauma, anxiety, depression and the like. As mentioned, one can often be a reason for bringing about the other, but they need not always be mutually inclusive either. Both physical and mental stress is directly linked to erectile dysfunctions though.

If the body is worked to a point of extreme tiredness, it simply may not have enough physical and/or mental energy to power and hold an erection. On the other hand, mental stress creates a distraction for the brain in a negative manner, which keeps it from acting in the way that it should in presence of sexual stimuli. ED caused by physical stress can be easily recovered from with a proper diet and restful sleep, unless it has been going on for a significant while at a stretch.

When the body is being stressed continuously without the sufficient rest and nutrition it needs, that will lead to mental stress accumulation as well. When left unaddressed for a long enough period, the impotence from such cases can take a long time to heal, if at all possible. Mental stress has the same effect and it can disrupt sleep, which is absolutely crucial for the body to recover and be productive during sexual activities. In fact, both physical and mental stress can lead to low testosterone levels, which would then require professional help, as mentioned previously.

Only a doctor with the necessary expertise (endocrinologist or urologist) and experience can help patients uncover the real reason/reasons behind their ED episodes. Even if you believe that you are aware of the cause and it isnt anything to worry about too much, get yourself checked. On the other hand, if it happens only in very rare circumstances, chances are that you have nothing to worry about. Keep an eye on the frequency though, and consult a doctor immediately if the ED episodes seem to be increasing in their occurrence. Not only is that necessary to maintain healthy conjugal relationships, but medical investigations may also reveal one of the more serious causes that we already discussed.

Read more from the original source:
Erectile Dysfunction: A Look at the Most Common Causes - Feed Leader


Oct 8

Coronavirus could cause infertility in men – according to a new study – Derry Journal

Men who suffer from severe cases of coronavirus could experience problems with fertility, a new study has warned.

Dr Dan Aderka, from the Sheba Medical Centre in Israel, conducted the study and believes that the virus also impaired sperm motility, due to damage to testicular cells.

Reduced sperm volume and motility

For the study, Dr Aderka screened healthy men for evidence of coronavirus and found that, in some cases, the virus had made its way into their sperm.

It was also found that there was a 50 per cent decrease in sperm volume, concentration and motility among patients with moderate coronavirus symptoms, even 30 days after their diagnosis.

Post-mortem tests of 12 Covid-19 patients also demonstrated moderate to severe changes in the testicular cells that support sperm development and those producing testosterone, the hormone that induces sperm division and multiplication.

Speaking to the Jerusalem Post, Dr Aderka said, As normal sperm maturation takes 70 to 75 days, it is possible that if we are doing a sperm examination two and a half months after recovery, we may see even more reduced fertility. It could be even more detrimental.

Destroying testicular cells

Coronavirus can destroy two types of cells in the testicles, sertoli and leydig, according to Dr Aderka. Sertoli is responsible for sperm maturation, while leydig produces testosterone. Coronavirus can bind to the ACE2 receptors on the surface of these cells and destroy them, as it can also do in the lungs.

He said, Interestingly, an enzyme called TMPRSS2 assists the virus in binding to the ACE receptor, facilitating its internalization into the cells.

This phenomenon may explain the higher Covid-19 morbidity and mortality of men compared to women.

He also added that this may also explain the lower morbidity and mortality of children, whose testosterone levels are low.

Dr Aderka said it is still unclear if this effect is reversible, or if it is possible for men to recover over time. The Sheba Medical Center plans to examine the same patients it screened in six months and a years time to examine any changes.

Read more from the original source:
Coronavirus could cause infertility in men - according to a new study - Derry Journal


Oct 5

Scott Disick learns he has low testosterone, admits his body has been through ‘some rough waters’ – CNN

At first, the reality star, who shares three kids with Kourtney Kardashian, originally thought he had contracted Covid-19, saying, "Lately, I've just had no energy to do anything. I wake up and I'm just shot."

He went on, explaining, "I don't have the drive to get up and run around with my girlfriend and my kids. I just don't have the energy. I don't know if I'm getting old or I'm just not in great shape, but I just want to see if there's anything wrong with me."

"I'm definitely a drop nervous to do all these blood panels, because I've put this vessel through a lot of trauma, I'm not going to lie," he said. "I'm definitely scared, but if there's anything wrong with me, whatever is the best way to get my body functioning better is what I'm going to do."

He added that his body has taken a beating.

"I feel like there's definitely been some stress in my life," he continued. "Missing my parents, it's really hard. My life hasn't always been easy. I used to drink and party and go out a ton, so my body, it's been through some rough waters and taken some pretty bad beatings. I never thought that there was a possibility any of that stuff could affect me in the long run."

Disick has openly checked himself into rehab before.

When his blood results came back, Disick was told that his testosterone levels were "clinically low."

"I'm very thankful that there was nothing serious," he said. "It could be from a number of reasons, so my doctor suggested I meet with a nutritionist, who did a more detailed blood test to find out why my testosterone is so low and to see exactly what's working and what's not working on my body."

He has since changed his diet and is now taking supplements.

Read the original:
Scott Disick learns he has low testosterone, admits his body has been through 'some rough waters' - CNN


Oct 5

Covid-19 could lower testosterone levels and libido in men – heres what the new study found – Shields Gazette

Covid-19 could lower testosterone levels and libido in men - heres what the new study found(Photo: Shutterstock)

A new study has revealed that men who contracted Covid-19 have their testosterone levels lowered by 30 per cent, on average.

Even two thirds of men who showed no symptoms reported a loss of libido.

Researchers in Turkey analysed levels of sex hormone in 232 men who were hospitalised after they tested positive for Covid-19.

What is hypogonadism?

More than half (51 per cent) of the men had developed a condition called hypogonadism, meaning their bodies did not produce enough testosterone.

On average participants levels were drained by 30 per cent post-infection, to borderline unhealthy levels.

Academics from the University of Mersin who ran the study claim there is a direct correlation between severe illness and lower testosterone levels.

Lead author, Professor Selahittin ayan (a urologist at the university) said, In our study, the mean total testosterone decreased, as the severity of the Covid-19 increased.

The mean total testosterone level was significantly lower in the ICU group than in the asymptomatic group.

In addition, the mean total testosterone level was significantly lower in the ICU group than in the standard care group.

Why do men need testosterone?

Testosterone is key to the development of sex organs and muscle growth. The hormone also helps regulate the bodys immune responses, including fighting off viral infections.

Low levels have been linked to an increased risk of dying from the flu, as well as inflammation, heart disease and high blood pressure.

A healthy level of testosterone is usually considered to be above 300 nanograms per decilitre (ng/dl).

Results in the study showed that patients saw their levels drop by a third, on average, from 458 ng/dl to 315 ng/dl.

Professor ayan describes the uses of the hormone saying, Testosterone is associated with the immune system of respiratory organs, and low levels of testosterone might increase the risk of respiratory infections.

Low testosterone is also associated with infection-related hospitalisation and all-cause mortality in male in ICU patients, so testosterone treatment may also have benefits beyond improving outcomes for Covid-19.

See the original post here:
Covid-19 could lower testosterone levels and libido in men - heres what the new study found - Shields Gazette


Oct 5

Testosterone Replacement Therapy Market Industry Development Trends & Competitive Analysis by Leading Industry Players – The Daily Chronicle

The testosterone replacement therapy market is segmented on the lines of its product type and ingredient type. Based on product type the testosterone replacement therapy market is segmented into oral, implants, gums/ buccal adhesives, injections, patches and creams/ gels. The testosterone replacement therapy market is segmented on the lines of its ingredient type like testosterone, testosterone cypionate, testosterone enanthate, testosterone undecanoate and methyl testosterone. The testosterone replacement therapy marketis geographic segmentation covers various regions such as North America, Europe, Asia Pacific, Latin America, Middle East and Africa. Each geography market is further segmented to provide market revenue for select countries such as the U.S., Canada, U.K. Germany, China, Japan, India, Brazil, and GCC countries.

Browse Full Report: https://www.marketresearchengine.com/upcommingreport/testosterone-replacement-therapy-market

Testosterone is responsible for the improvement of male sexual characteristics and this hormone formed by the testicles. It is also important to maintain various functions such as sexual function, bone growth, adequate levels of red blood cells, and a sense of well being and muscle bulk. Insufficient production of testosterone causes erectile dysfunction. Erectile dysfunction occurs due to decreased testosterone production to overcome this testosterone replacement therapy is used to improve the problem. Testosterone replacement therapy occurs in various forms containing its own set of advantages and hazards such as subdemal pellets, transdemal patches and injections. Testosterone replacement therapy also helps to recover symptoms of low testosterone. Low testosterone is caused due to age growth it generally lowers down after the mid 30s and further decreases accordingly to the age factor.

The scope of the report includes a detailed study of global and regional markets of Testosterone Replacement Therapy Market. The reasons given for variations in the growth of the industry in certain regions.

Global Testosterone Replacement Therapy Market is expected to exceed more than US$ 1.0 billion by 2024 at CAGR of 4% in the given forecast period.

The major driving factors of testosterone replacement therapy market are as follows:

Rise in incidence of testosterone deficiency.Increase in geriatric populace with high risk of testosterone deficiency.Increasing awareness about testosterone substitute therapy.

The restraining factors of testosterone replacement therapy market are as follows:

High possibility of side effects associated to testosterone replacement therapy.Patent expiry of key drugs and entry of generics.

The report covers detailed competitive outlook including the market share and company profiles of the key participants operating in the global market. Key players profiled in the report include AbbVie, Inc., Allergan plc, Bayer AG, Endo Pharmaceuticals, Inc., Eli Lilly and Company, Kyowa Kirin International plc, Mylan N.V., Novartis AG, and Pfizer, Inc. Company profile includes assign such as company summary, financial summary, business strategy and planning, SWOT analysis and current developments.

The Testosterone Replacement Therapy Market has been segmented as below:

The Testosterone Replacement Therapy Market is Segmented on the lines of Product Type Analysis, Ingredient Type Analysis and Regional Analysis. By Product Type Analysis this market is segmented on the basis of Oral, Implants, Gums/Buccal Adhesives, Injections, Patches and Creams/Gels.

By Ingredient Type Analysis this market is segmented on the basis of Testosterone, Testosterone Cypionate, Testosterone Enanthate, Testosterone Undecanoate and Methyl Testosterone. By Regional Analysis this market is segmented on the basis of North America, Europe, Asia-Pacific, MEA and Rest of the World.

This report provides:

1) An overview of the global market for testosterone replacement therapy and related technologies.

2) Analyses of global market trends, with data from 2015, estimates for 2016 and 2017, and projections of compound annual growth rates (CAGRs) through 2024.

3) Identifications of new market opportunities and targeted promotional plans for testosterone replacement therapy.

4) Discussion of research and development, and the demand for new products and new applications.

5) Comprehensive company profiles of major players in the industry.

Request Sample Report from here: https://www.marketresearchengine.com/upcommingreport/testosterone-replacement-therapy-market

Table of Contents

1 INTRODUCTION

2 Executive Summary

3 Global Testosterone Replacement Therapy Market Industry Analysis

4 North America Testosterone Replacement Therapy Market Analysis

5 Europe Testosterone Replacement Therapy Market Analysis

6 Asia Pacific Testosterone Replacement Therapy Market Analysis

7 Middle East and Africa (MEA) Testosterone Replacement Therapy Market Analysis

8 Latin America Testosterone Replacement Therapy Market Analysis

9 Global Testosterone Replacement Therapy Market, Country Snippets

9.1. Global Testosterone Replacement Therapy Market Revenue, by Country, (US$ Mn), 201420249.2. U.S. Testosterone Replacement Therapy Market Revenue, (US$ Mn), 201420249.3. Japan Testosterone Replacement Therapy Market Revenue, (US$ Mn), 201420249.4. Germany Testosterone Replacement Therapy Market Revenue, (US$ Mn), 201420249.5. U.K. Testosterone Replacement Therapy Market Revenue, (US$ Mn), 201420249.6. Canada Testosterone Replacement Therapy Market Revenue, (US$ Mn), 201420249.7. China Testosterone Replacement Therapy Market Revenue, (US$ Mn), 201420249.8. Brazil Testosterone Replacement Therapy Market Revenue, (US$ Mn), 201420249.9. Mexico Testosterone Replacement Therapy Market Revenue, (US$ Mn), 201420249.10. United Arab Emirates (UAE) Testosterone Replacement Therapy Market Revenue, (US$ Mn), 20142024

10 Company Profiles

10.1. AbbVie, Inc.

10.2. Allergan plc

10.3. Bayer AG

10.4. Endo Pharmaceuticals, Inc.

10.5. Eli Lilly and Company

10.6. Kyowa Kirin International plc

10.7. Mylan N.V.

10.8. Novartis AG

10.9. Pfizer, Inc.

Other Related Market Research Reports:

Topical Drug Delivery Market Size, Industry Share, Approaches and Forecast By 2022

Tuberculosis Testing Market is Expected to Get US$ 2600 Million By 2022

Urinary Tract Infection Treatment Market is Expected to Grow US$ 10 Billion By 2024

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Testosterone Replacement Therapy Market Industry Development Trends & Competitive Analysis by Leading Industry Players - The Daily Chronicle


Oct 5

Notre Dame professor publishes study with new insights on fatherhood – Observer Online

Recently published in Nature Magazines Scientific Reports, Dr. Lee Gettler, an associate professor of anthropology at Notre Dame, has completed a new study which links testosterone levels in fathers with their broader cultural settings.

Gettler said that he became interested in his research when he met Dr. Adam Boyette, who is now a senior researcher at the Max Planck Institute for Evolutionary Anthropology, at a conference put on by the Jacobs Foundation.

[The Jacobs Foundation] put together a conference that was specifically bringing together a really large group of scholars who specifically studied fathers from diverse perspectives psychology, sociology, neuroscience, anthropology to try to get all these people in the same room to talk about how we can begin to kind of best understand the way that fathers impact human children, Gettler said.

A father from the BaYaka tribe poses for a photo with his young sonin the northern Republic of Congo, where Boyette did his field work.

Boyette did his dissertation research in a remote region in northern Republic of the Congo accessible by a weeklong journey from the capital city of Brazzaville. There he studied the BaYaka and Bondongo people who live a very different lifestyle than one were used to. Although located in the same village, the two tribes have their own distinct cultures. The BaYaka people are a more egalitarian society, focused on cooperative living, whereas the Bondongo people are fisher-farmers whose society is hierarchical and status-based.

Boyette noted that the differences between these two communities who live in such close conjunction is really what drew their study to this remote corner of the world.

Our interest was to work with both groups and try to understand differences and look to see if there were differences in fathering that are related to cultural differences, including things like variation in the family systems and what fathers do in the community, Boyette said.

They hypothesized that the testosterone levels of the BaYaka men and Bondongo men were different. Testosterone, a hormone which has been shown to decrease in men when entering fatherhood in some cultural settings, can be associated with physical strength and aggression. Gettlers team hypothesized that since the BaYaka fathers place more emphasis on community and generosity, their testosterone levels will be lower than the Bondongo fathers, who are valued more for their strength and being a good resource provider.

When the researches had an opportunity to collaborate via funding from the Jacobs Foundation, Boyette said that he and Gettler jumped at the chance.

[The Jacobs Foundation] offered us this opportunity to apply for funding to work on projects together, Boyette said. It was a really fantastic opportunity and Lee and I right away saw a really good opportunity to collaborate because we both had different skill sets that we recognized would work well together.

Before the two could conduct any formal research, they had to connect with the communities and get settled.

The first summer of our grant, [Boyette] went to field site and just basically was hanging out to gain trust with the communities to talk to them about Heres what were interested in, were interested in learning about your communities and heres what we would do, Gettler said. [Boyette was] getting permission from the communities, particularly the elders and the leadership councils in the community, to make sure that they were that it was acceptable to them, ethically, that we do this work.

Boyette said that the work was challenging, and it would not have been possible without the help of others who blazed the trail for him.

Another challenge faced by the team was how to transport their materials. Gettler explained that this was an especially difficult project because they needed to transport large liquid nitrogen jugs to store saliva samples containing information about testosterone from the BaYaka and Bondongo men.

If we look at testosterone in saliva, it correlates really strongly to what is circulating in the blood in the body, but its obviously much less invasive than collecting blood so thats the benefit, Gettler mentioned. Part of the reason that there are few studies in this kind of relatively remote setting is because of the challenges of dealing with the biological markers.

Boyette explained that they had to modify their travel plans in order to transport the materials to the remote communities because the canisters of liquid nitrogen need to be closely monitored at all times to prevent spillage.

The researchers also struggled with the problem of how to quantify how the different cultures viewed fatherhood and how to decide who were the good fathers.

Gettler explained that the team conducted a series of long interviews with the villagers to get a sense of the values that were sought after in a good father.

[Boyette and his team] spent a lot of time doing semi-structured qualitative interviewswed call that data ethnography, Gettler said. Our real goal was to try to understand how these communities are defining what a good father is and then can we find a way to operationalize that to get at whether good fathers, based on local values, have healthier kids.

Once they had sorted out the cultural ideas of fatherhood, the researchers had each respective father rank each other on the main values pointed out by each community. The questions that the fathers ranked each other by varied between the BaYaka and Bondongo groups: The BaYaka cultural ranked good fathers based on how they shared resources, how hard they worked, whether they had any spousal arguments, whether their children were healthy and if they contributed to community teaching. On the other hand, the Bondongo people ranked good fathers based on fishing/hunting abilities, how big their gardens were, if they traveled to get commercial goods for the community, if they had healthy children and if they contributed to social education.

Boyette said that the different questions actually revealed a lot about the communities. He explained that they found that the Bondongo fathers were actually sorted into two groups: one of the groups of fathers focused more on the hard, laborious chores of fishing and hunting, and the other group focused on the teaching of children and staying closer to the community. As Boyette and Gettler expected, the group of Bondongo fathers that focused on the strength intensive tasks had higher levels of testosterone than the group that focused more on the children. With the BaYaka tribe who are more focused on cooperative communities, the researched noted lower levels of testosterone in men who were ranked as better fathers.

The team also noted a correlation between testosterone levels and martial arguments. They found that fathers in both communities who were rated as having more martial conflicts had higher testosterone levels.

Gettler and Boyette both agree that their study has impacts outside the remote village in the Republic of Congo. Boyette said that he believes this study shows us that there is not just one way to be a great father.

Theres not one good way that men should be contributing to their families and we have to recognize that men see themselves as coming from particular different cultural backgrounds and that these may also suit their biology better or are promoted by their biology in different ways, Boyette said. We should be able to welcome various ways of being fathers and different ways of contributing to the child development and supporting.

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Notre Dame professor publishes study with new insights on fatherhood - Observer Online


Oct 5

Sex Life, Sex Drive, and Menopause: News from NAMS 2020 – Everyday Health

In the last few years there has been more research around sexual function during the menopause transition in areas such as low libido or pain during intercourse, but very little specifically focused on how important sex is to women during this time, says Holly N. Thomas, MD, assistant professor of medicine at the University of Pittsburgh in Pennsylvania. Dr. Thomas is the lead author of research presented on the topic of the importance of sex in women as they age at the 2020 Virtual Annual Meeting of The North American Menopause Society (NAMS), which opened on September 28, 2020.

We were interested in looking at how womens ratings of how important sex was to them changes or stays the same as they move through the menopausal transition, says Thomas.

To find out the answer, investigators studied a total of 3,257 women from The Study of Womens Health Across the Nation (SWAN), all of whom completed 14 evaluations over 15 years. Visits included interviews, questionnaires, blood draws, and biometric measures such as body mass index (BMI), blood pressure levels, hormone levels, and depression symptoms.

RELATED: 10 Symptoms of Menopause and Perimenopause

Women were asked to rate how important sex was to them with the choices of not at all, not very, moderately, quite, or extremely.

Rather than look at averages of the women over time, investigators looked at trajectories within the cohort. This analysis technique allowed us to see if there are unique pathways that women can follow, explains Thomas.

If you just looked at averages of the group as a whole, it would look like how important sex is to women would go down for everyone, but what we actually found three distinct pathways women commonly follow when it comes to how much they value sex as they get older, she says.

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For the largest group, about 45 percent of the women, sex did become less important to them as they went through their forties and fifties and early sixties, says Thomas. For 27 percent of the women, sex remained highly important to them throughout midlife, and for 28 percent of the women sex was not very important to them throughout the whole duration of midlife, from forties to sixties.

Its important to recognize not all women are going to follow the same pathway when it comes to sex at midlife, each woman has her own unique experience, says Thomas.

There were a few trends that Thomas and her team noticed.

These results show that its not necessarily true that sex becomes less important to all women at midlife and that its just an inevitable fact of aging, says Thomas.

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My takeaway was that we need to be more routinely asking women in midlife about their sexual function and whether there are barriers such as having pain during intercourse or if theyre having problems with low sexual desire thats bothering them, says Stephanie Faubion, MD, director of the Mayo Clinic Center for Womens Health in Rochester, Minnesota, and medical director of NAMS.

Sexual function is usually under addressed in women in general but certainly in women beyond menopause, adds Dr. Faubion.

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In general, women who have a good sex life before menopause have a good sex life after menopause, she says. This research indicates that if sex is important to a woman before menopause, its important after.

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Keep in mind that sex doesnt look the same with aging, says Faubion. We have to modify our expectations about sexual functioning as we get older. Sex may not be always be penis and vagina sex; I have that conversation often with my patients, she says.

As peoples bodies and health changes, including medical illnesses that can be experienced by both men and women, we may need to modify what we are doing, but nonetheless, sexual intimacy remains important to all people for as long as they live, says Faubion.

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About 30 percent or so of women in the United States report low libido or sex drive, and about 10 percent report being bothered or distressed by it, Brooke Faught, doctor of nursing practice and board-certified women's healthcare nurse practitioner, who is clinical director of the Womens Institute for Sexual Health in Nashville, Tennessee. Dr. Faught presented on sexual health, libido, and testosterone at the NAMS 2020 conference.

Having a low sex drive isnt automatically a reason for treatment; hypoactive sexual desire disorder (HSDD) is when women have a low libido and are bothered or distressed by it. If the patient isnt directly impacted or bothered by it and its not impacting their daily function, its not a true diagnosable condition, says Faught.

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Even when they are bothered by a lack of desire, many women put up with it rather than seek treatment; they think its a normal part of aging or something they should just deal with, she says.

One barrier that stands in the way of treating HSDD is the lack of an U.S. Food and Drug Administration (FDA)approved testosterone for women with HSDD, even though there is quite a bit of published research on how and when to use it, says Faught.

Faubion agrees, saying Testosterone is fairly well studied for sexual health in women and is effective in almost all areas of sexual function.

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The barrier that exists isnt lack of science or lack of interest, its the FDA, says Faught. The FDA has asked for more long-term data for using testosterone in hypoactive sexual desire disorder (HSDD) in women, potentially up to five years [worth], she says.

A study that would fulfill the FDAs request seems to be cost prohibitive for pharmaceutical companies, says Faught. I dont know of any specific product that is on the cusp of getting approval or seeking approval, which is unfortunate and frustrating, she adds.

There are options and guidance for how to use testosterone products for HSDD, says Faught. In 2018, the International Society for the Study of Womens Sexual Health (ISSWSH) published a process of care (POC) for the diagnosis and management of hypoactive sexual desire disorder (HSDD) in pre- and postmenopausal women, including guidelines for prescribing testosterone in postmenopausal women with HSDD.

A global consensus statement that was endorsed by several international medical societies including The International Menopause Society, The Endocrine Society, and the NAMS was published in The Journal of Clinical Endocrinology & Metabolism in October 2019. The statements purpose is to provide clear guidance on which women may benefit from testosterone therapy, as well as any potential risks.

The issue is that treating off-label can carry additional risk and expense for patients, says Faught. If I prescribe a testosterone product thats intended for men, I can prescribe it at a lower dose as is necessary, but because it isnt FDA approved for this use, usually insurance wont cover it. That could mean a cost of anywhere from $300 to $500, she says.

Compounding testosterone, a process where a pharmacist specifically makes the product from scratch may be cheaper, but then there is increased potential for human error as well as a lack of regulations, says Faught.

Probably the main reason there is no FDA-approved testosterone product for HSDD is that theres a lack of long-term safety data, says Faubion. For example, we dont know breast cancer risk, we dont know cardiovascular risk, she says.

The cardiovascular risk appears to be less of concern for women than it is for men taking testosterone, but the bigger question is breast cancer risk over time, says Faubion. This is because testosterone converts to estrogen inside the body, and so there is a question on whether that increases breast cancer risk, she says.

Ive used it in my practice and its effective for women, says Faubion. Yes, we still have questions about long-term safety and long-term efficacy, but for short-term efficacy and short-term safety, we have pretty convincing data; I think ultimately it probably will be approved for use in women.

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Hot Flash Treatment News: 4 Takeaways From NAMS 2020

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Sex Life, Sex Drive, and Menopause: News from NAMS 2020 - Everyday Health



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