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Mar 22

Whole body vibration could provide some exercise benefits to obese patients – The Augusta Chronicle

Whole body vibration could provide exercise benefits to obese patients who might otherwise have trouble working out and could affect metabolic factors that are implicated in diabetes and other diseases, according to research at Augusta University.

Working in a mouse model for obesity and Type 2 diabetes, the AU team found that daily whole body vibration passive treatment on a machine that shakes the patient had effects similar to treadmill exercise on metabolic factors such as glucose levels and insulin sensitivity and had on muscles compared with sedentary mice, according to research published in the journal Endocrinology.

The effect on bones was more mixed, with modest changes in bone structure but higher circulating levels of the bone hormone osteocalcin, compared with sedentary mice.

The research, which already has received much attention, prompted two of the authors to clarify what it means.

A lot of people assume, just from the title, that were saying that whole body vibration should replace exercise, said Dr. Meghan McGee-Lawrence, the lead author. Thats not what we are saying. We are saying this is another option for individuals that may not be able to participate in ordinary, traditional exercise programs, for a number of different reasons.

Only obese-diabetic mice responded to the whole body vibration or treadmill exercise, which was at a level well below what normal mice would do in a week, said Dr. Alexis Stranahan, the corresponding author on the paper.

The impact on metabolic factors and the increase in some bone-forming elements is of interest to researchers such as McGee-Lawrence who work in the bone field; there havebeen intriguing findings in mice about the interaction between the two.

But realistically, the clinical research isnt there to back it up right now, she said. While we know that bone has an important endocrine role in the body, I think the mechanisms by which it does that, including the role of osteocalcin, are up for debate.

whole body vibration was hot in the bone field in the late 1990s and early part of this century but lost a lot of interest when it was found to be ineffective in addressing one of the largest problems, postmenopausal osteoporosis, McGee-Lawrence said. There is now research in humans looking at its effects on health problems such as metabolic disorders and cardiovascular disease and bone health, she said.

Those studies are ongoing right now and they are producing a lot of exciting results, McGee-Lawrence said.

The AU research is important because the two interventions are not often compared, Stranahan said.

Side-by-side comparisons are definitely lacking in both the human and the animal model literature, she said. And I think it is useful to compare the two because it can help to tailor and say, OK, whole body vibration mimicked the metabolic effects of exercise but the effects at the level of bone structure were not that extensive.

That might help point the way to where whole body vibration would be more effective for some people or some problems than others, Stranahan said.

Though the effect of whole body vibration on bone remains to be clarified, There are a lot of other beneficial effects and finding the body systems that will best benefit from it is really, I think, the way to move forward, McGee-Lawrence said.

Reach Tom Corwin at (706) 823-3213

or tom.corwin@augustachronicle.com.

See the original post:
Whole body vibration could provide some exercise benefits to obese patients - The Augusta Chronicle

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