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Muscle weakness is a hallmark symptom of type 2 diabetes and could be recognized with a simple Handgrip strength test.

Diabetes

British and Finnish researchers suspect that the strength of a handgrip could help identify people with type 2 diabetes. This is an alternative to blood glucose monitoring, the current screening measure. The results of the study were published in the Annals of Medicine.

Read Also: Type 1 Diabetes: Transplanting Pancreatic Cells Without Anti Rejection Drugs May Soon Be Possible

Muscle weakness is one of the hallmarks of type 2 diabetes and can be tested with a handgrip strength test. To reach this conclusion, the researchers conducted their study with 776 volunteers aged between 69 and 72 years for almost 20 years. The patients were subjected to four resistance tests, which were performed with a hand dynamometer at four different points in time: at the beginning of the study, 4 years later, 11 years later and finally 20 years later. The results showed that the probability of being diabetic decreased by 50% with each additional unit of strength. This correlation is greater than several factors recognized as possible causes of diabetes: age, family history, smoking, high blood pressure, physical activity, and even blood sugar levels.

Read Also: Diabetes Can Lower HGH Levels, Study Suggests

This provides a credible alternative to screening for the disease. These results may have implications for the development of prevention strategies for type 2 diabetes, confirms Kunutsor Sector, lead author of the study. Measuring the strength of a handgrip is simple, inexpensive, and does not require special knowledge or resources; it could potentially also be used for the early detection of people at high risk of developing type 2 diabetes.

To confirm these results, further studies are needed to consider the use of this diabetes detection strategy. In a previous meta-analysis of ten studies, the same researchers showed that people with a high handgrip strength have a 27% lower risk of developing the disease. The new study confirms that reduced muscle strength is one of the symptoms oftype 2 diabetes.

Read Also: Diabetes: Researchers Make a Breakthrough in Finding a Permanent Cure

Handgrip strength improves prediction of type 2 diabetes: a prospective cohort study

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Type 2 Diabetes Can Be Predicted With a Simple Handgrip Strength Test - Gilmore Health News

Global Thermal Scanners Marketreleased by Fior Markets studies the current market standing with future trends that can affect the market growth rate and cover the major growth prospect over the forthcoming years from 2020 to 2027. The report comprises detailed information regarding the market size, market performance, key trends, and market dynamics of the market. The report offers a robust assessment of the globalThermal Scannersmarket that comprehends market new product analysis, financial overview, marketing trends, as well as key strategies and plans prepared by the major players. The study provides a critical assessment of the emerging competitive landscape of the manufacturers. It also describes the market components such as product types and end-users in detail with explaining which component is expected to expand significantly in this market.

NOTE: Our analysts monitoring the situation across the globe explains that the market will generate remunerative prospects for producers post COVID-19 crisis. The report aims to provide an additional illustration of the latest scenario, economic slowdown, and COVID-19 impact on the overall industry.

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Competitive Analysis:

For each manufacturer covered, this report analyzes its manufacturing sites, capacity, production, ex-factory price, and revenue and market share in the globalThermal Scannersmarket. The report covers a detailed performance of some of the key players and analysis of major players in the industry, segments, applications, and regions. The progress of leading players is analyzed based on crucial parameters, including market share, new developments, global reach, local competition, price, and production. The report also covers the recent agreements including merger and acquisition, partnership or joint venture, and the latest developments of the manufacturers.

The competitive environment and market fragmentation:Opgal, Seek Thermal, Leonardo S.p.A., Axis Communications AB, Tonbo Imaging, C-THERMAL, Infratec GmbH, Terabee, AMETEK Land, HGH Infrared Systems, Fluke Corporation, VUMII Imaging, Optotherm, Inc., L3harris Technologies, Inc., FLIR Systems, Inc., Thermoteknix Systems Ltd., Xenics, Testo SE & Co. KGaA, Cox, HGH Infrared Systems, and 3M Scott among others.

By regions, this report splits the globalThermal Scannersmarket into several key regions, with sales, revenue, price and gross margin market share of top players in these regions, from 2020 to 2027 (forecast), like:North America, Europe, Asia Pacific, South America, and the Middle East and Africa.

On the basis of the product, this report estimates the sales volume, revenue (Million USD), product price, market share, and growth rate of each type. Also on the basis of the end users/applications, this report focuses on the status and outlook for major applications/end users, sales volume, market share, and growth rate for each application. The worlds main regions are covered along with the product price, profit, capacity, production, supply, demand, and market growth rate, and forecast. Regional growth is explained along with the scope, marketplace size, and profit in this globalThermal Scannersmarket.

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Global Thermal Scanners Market 2020 with Covid-19 Impact Analysis and Forecast by 2027 - Red & Black Student Newspaper

The endocrine system is responsible for regulating hormones. Typically, people associate hormones with functions such as reproduction and regulating temperature and metabolic function. However, it also has a close relationship with creativity.

Source: europeanbusinessreview.com

Creativity can come in two main forms: artistic expression and problem-solving. Artistic expression is usually emotion-driven, and the endocrine system is responsible for mood regulation. When in balance, hormones can help emotions stay in stable state. This can help people stay clear-minded when refining their art.

Meanwhile, hormones such as serotonin and dopamine lead to increased feelings of happiness, which can give people more energy and make them want to create something. In addition, the action of creating can affect the endocrine system. Participating in creative activities can increase the release of serotonin and dopamine in the brain, which has a positive effect on the endocrine system and can promote additional creativity.

Hormones that people typically associate with negative emotions have a more complicated relationship to creativity. Imbalances of hormones such as human growth hormone can increase the risk of depression. While some people use art as a mechanism to cope with sadness and depression, others feel more tired or hopeless and may have trouble being creative. Luckily, the release of serotonin and dopamine when a person can convince themselves to create something can start to reverse the negative impact of hormonal imbalances on the persons mood.

An excess of cortisol, the stress hormone, can also make it more difficult to be creative. In some cases, cortisol can improve a persons memory of emotional events, which they can later use for inspiration. However, it also pulls energy away from high-level cognitive functions such as art and channels it into fight-or-flight mechanisms. Again, creativity can help regulate cortisol imbalances since art relieves stress.

Source: medium.com

Just as the endocrine system is important for artistic creativity, it is also important for creative problem-solving and cognitive function. The sex hormones are especially important.

Estrogen serves many functions: It helps protect the brain and promotes brain cell creation. It helps with verbal cognitive skills such as language fluency and the ability to retain and learn from information transmitted verbally. This skill is especially useful for writers and actors. It improves fine motor skills, which are necessary to create art.

HGH and Testosterone are also very important. It helps with visuospatial ability, which has many practical uses in addition to being useful for three-dimensional art and proportional drawings. It increases the ability to problem-solve in a logical or mathematical way. It helps people remember the things they have seen, which can be a source of artistic inspiration.

Although these hormones are among the most important for cognitive function, imbalances of any hormone can result in impaired cognitive function. Metabolic hormones such as human growth hormone regulate energy levels, so a deficit can make it more difficult to think. Here you may get more information about growth hormone deficiency in adults hghtherapydoc.com.

Human growth hormone is also connected to thinking in that it is involved in adult brain functions such as learning, memory, locomotion, neuroprotection, and psychological behaviors. There are HGH receptions in several brain areas as well. In addition to the pituitary gland and liver being the primary areas of producing hormones like the growth hormone, the GH is one of two substances being identified within the brain.

Researchers have identified the growth hormone as a protector against several brain issues including traumatic brain injury and degenerative diseases, according to government studies.

Production of this crucial element starts slowing down at age 40 with adults losing up to 15 percent of HGH production every 10 years. That can cause a host of aging symptoms such as a loss of energy, loss of muscle mass, and a reduction of bone density. It can also cause a loss of creative thinking ability.

High levels of cortisol also reduce cognitive function to an instinctive fight-or-flight response. One of the roles of the endocrine system is to facilitate cell health and communication, so a healthy brain and high levels of cognitive function are impossible without hormonal balance.

Source: abcmuzic.com

Artistic creativity does not come in just one form. It can be visual art, acting, writing and many other media. However, the effects of the endocrine system on creativity remains the same for artists no matter what their media of choice may be.

Growth hormone is important for creativity. After helping children grow, it helps the body repair cells, so it can help repair the brain. It also helps regulate metabolic function. An HGH imbalance can lead to low energy levels, depression and decreased cognitive function. Because of these problems, it can stunt self-expression and make it more difficult for artists to be creative and perform their best.

Human growth hormone replacement therapy can help artists with HGH deficiencies. HRT can re-regulate the endocrine system and reverse the effects of the deficiency. Then, creative people will be able to get back to their favorite forms of expression.

Source: medium.com

The endocrine system is vital to creativity and cognitive function. Hormones can increase creativity, and creativity can boost the mood by increasing dopamine and serotonin levels. The brain also cannot function without balance in the endocrine system.

Growth hormone deficiency is one hormone that can lead to a decrease in creativity and cognitive function, making it difficult for artists to express themselves. If you are experiencing this difficulty, get tested for hormone deficiency. Hormones naturally decline as people age and a natural decline doesnt qualify you for treatment. You must have an unnatural hormone deficiency to legally obtain growth hormone treatment from an HRT clinic.

Continue reading here:
Creativity And Endocrine System: Is There a Connection - 2020 Guide - VideoInk

Study on the Global Human Growth Hormone (HGH) Market

The market study on the Human Growth Hormone (HGH) market published by Fact.MR highlights the essential parameters that are expected to shape the growth of the Human Growth Hormone (HGH) market in the upcoming years. The report maps the trajectory of the Human Growth Hormone (HGH) market by taking into account historical data for the period between 20XX-20XX and considering 20XX-20XX as the forecast period.

The presented study evaluates the different factors that are likely to influence the dynamics of the Human Growth Hormone (HGH) market including the current trends and recent developments on the technological front. In addition, the micro and macro-economic factors that are likely to impact the growth of the Human Growth Hormone (HGH) market during the assessment period are assessed in detail.

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Segmentation of the Human Growth Hormone (HGH) Market

The analysts have segmented the Human Growth Hormone (HGH) market into various sections to offer a microscopic understanding of the market. The different segments studied in the report include:

Competitive landscape

Critical insights enclosed in the report:

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The report aims to provide answers to the following questions related to the Human Growth Hormone (HGH) market:

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Innovations in the Human Growth Hormone (HGH) Field Likely to Aid the Growth of the Human Growth Hormone (HGH) Market 2018 to 2028 - Scientect

Transparency Market Research points out that the competitive landscape in the global human growth hormone market is fairly consolidated. Players continue to focus on developing products with minimal side effects. To expand business to newer markets several vendors are looking at mergers and acquisitions.

Collaborations has become an important part of talent acquisitions for better drug development. For instance OPKO and Pfizer are collaborating to develop and sell human growth hormone hGH-CTP for treating adults and children. Some of the leading players operating in the global human growth hormone market are Merck KGaA, Eli Lilly and Company, Pfizer Inc., Novo Nordisk A/S, and Novartis AG.

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According to the research report, the global human growth hormone market is expected to be worth US$ 5,261.5 mn by the end of 2026 in terms of revenue. During the forecast years of 2017 and 2026 the global market for human growth hormone is projected to surge at a CAGR of 6.2%.

Out of the many routes of administration, the subcutaneous route of administration is projected to garner the highest revenue of US$1,600 mn by the end of 2026. It continuous to be the most preferred type of chronic growth therapy. From a geographic point of view, North America human growth hormone market is expected to remain in the leading position to strong presence of players.

Rising Incidences of Chronic Conditions amongst Children and Adults Boosts Uptake of Human Growth Market

The growing application of growth hormones in treating many diseases and conditions has created a plethora of opportunities for the global human growth hormone market. The global market for human growth hormone is also being driven by the increasing awareness about the effectiveness of growth hormones in rectifying short statures. Children suffering from congenital conditions have significantly benefited from growth hormones.

Meanwhile, adults with issues pertaining to pituitary gland have also led to a growing demand for human growth hormone therapies. Today, rising incidences of HIV/AIDS, growing research and development of long acting drugs, increasing cases of cancer, improving expenditure on healthcare, and commonly found growth hormone deficiencies have all augmented the global human growth hormone market.

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The research report also points out that rising incidences of pituitary tumors, neuropsychiatric-cognitive, skeletal abnormalities, neuromuscular, cardiovascular, and metabolic abnormalities are expected to seek human growth hormone therapies as effective solutions. Majority of these ailments can be alleviated with the help of growth hormones.

The report also states that the human growth hormone therapies are predominantly used for Tuner syndrome as these treatments are designed to treat poor sexual as well as physical developments. Thus, the increasing scope of application of human growth hormones is projected to take the global market to newer heights.

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Illicit Use of Drugs Likely to Hamper Global Human Growth Hormone Market

On the flip side, the global human growth hormone market is challenged by a few elements. The high cost of these drugs and therapies is the key reason holding the market back from achieving bigger market size. Additionally, illegal usage of growth hormones amongst sportsmen has become the biggest challenge for the global human growth hormone market. The report emphatically states that the adverse side-effects of these drugs is also been a major concern for the overall market.

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Human Growth Hormone Market Analysis and Research Report by Experts 2026 - thedailychronicle.in

True friendship propagates a certain sense of power among companions. Power to evoke an unparalleled share of our attention as we edify, incite and validate each other. Power to craft us into the best version of ourselves. Power to sculpt each others ideology and viewpoints with a degree of passion that we would never dare to brandish with anyone else.

And of course, our confidants harness the ever-treacherous temptation to get under our skin in ways that only they know best. With interpersonal knowledge comes the deep-seated license to ruffle our feathers, to agitate our firmest beliefs and insecurities on an effervescent whim. Annoyingly overzealous and effortlessly rattled conversationalist that I am, my closest circle of friends knows my ideological makeup like the back of their hands maybe I can partially blame The Observer for that. Their responsibility becomes a remarkably easy one: all it takes is a simple 21st century country music deserves wayyyy more credit or reality television destroys our morals text message for a mutual smirk to form through the phone.

The past weekend brought about a five-minute lull on my part as I carelessly thought that Id heard it all. Fittingly striking when I least expected it, a devastatingly alluring bait hooked my phone: Bill James sucks. With advanced analytics, baseball players just become assets to a business. The human aspects of the game are completely ruined.

I imagined a cackle trailing those words, not only because of my fervent discipleship of James, the pioneer of modern baseball analytics, but also because of its persistent relevance in the highly polarized clash between traditionalists and data-driven revolutionaries across major sports. Granted, reducing the near-ethereal miracle comeback, the unpredictable hot streak and the inspirational breakout story to conversations of distributions and deviations from the mean feels callous. Understandably, backlash behind statistically proven adjustments to game strategy, scouting and development heavily leans on consideration of historys control group: the generations of elite players that navigated their careers without the novelties of Statcast or extreme infield shifts.

And surely improvements in draft selections, scouting classes and on-field decisions through data insights bear benefits to the business side of baseball. With an ever-increasing body of metrics calculating the expected value of trade acquisitions and roster moves in light of upcoming game schedules, general managers and owners limit their time wasted on young projects or veteran gambles in farm systems and free agency. Player development that deliberately targets launch angle and exit velocity two metrics that can maximize offensive power at the plate yields massive surges in ticket and broadcasting revenue, capitalizing on homer-hungry fans. Pitching metrics like effective spin rate a measure of a pitchers efficiency in mechanics protect the invaluable assets of coaching staffs and executives by detecting potential causes of injuries before they occur.

But financial ploys aside, perhaps the crux of this widespread loathing for analytics in sports a distinctly human endeavor lies in our collective fear of science. We despise the thought of objective formulas and metrics overriding our years of experience watching and playing a game of metaphysical minds in motion. We cherish our imperfections in hope that we retain the autonomy to make our own decisions, however ineffective and misguided that they may be. The heart of the statistical matter beats to the rhythm of freedom, a refusal to act as data-driven pawns in a power-hungry struggle for competitive advantage.

Regardless of your stance on the forward-thinking baseball analysts that flood your television screen, however, the very nature of sports statistics protects against the very thing this argument criticizes. Take, for instance, Major League Baseball officials detection of widespread steroid use throughout the late 1980s and 1990s. The names Barry Bonds, Mark McGwire and Sammy Sosa soared to household status as they shattered seemingly unbreakable single-season home run records. While the trio of bombers painted a historical sensation, the 1997 Seattle Mariners colored a masterpiece of their own by tattooing 264 baseballs in a single season. Never before did fans witness home runs so majestic, so euphoric, so pivotal since the reign of Murderers Row.

Beneath all of the glamor in the new era of baseball, the Bay Area Laboratory Co-Operative (BALCO) perpetuated a sweeping scheme to catalyze the home run race. As later investigations confirmed, the laboratory administered supplements of human growth hormone (HGH), erythropoietin and other anabolic steroids while undetected for nearly 14 years. Investigations into the actions of BALCO began in 2002, a year after Barry Bonds attained an almost unthinkable feat: 73 home runs in 153 games played.

Basic applied statistics undoubtedly prompted the MLB to investigate. At base level, league executives and lawyers deemed the influx in long balls too significantly strayed from league averages for us to label Bonds performance as a random occurrence; chance alone does not justify his output at a reasonable level.

In this infamous case, analytics protected the humanity of Major League Baseball against the artificial development of steroids. By mining data from the performance of both past and present players, the MLB held Bonds, McGwire and Sosa to the standard of hitters greatest natural capacities and no more. Basic metrics derived an optimal level of performance under current conditions, and when enough players breached this deduction, commissioner Bud Selig administered a call for retribution.

But analytical methods are not anabolic steroids. When coaches remove their starting pitcher from the game after four strong innings, they act with the promotion of their teams refined success in mind. Chains of individual decisions and short bursts of focus define the identity of this game like no other, and certainly an agent like analytics should offer suggestions as a natural antidote for baseballs otherwise complex chaos.

Of course, more traditional choices reap rewards in many cases, and I might argue that human intuition should solely influence the dugout and bullpen as coaches evaluate the preparedness, health and energy of their players. But once the best nine assets for the job take to the field, or the spring training facility, or the off-season workout complex, analytics promote the deepest desire of friends: to help our beloved become the best version of themselves. If thats not humanizing, I dont know what is.

Above all, amidst the persistent teasing and flustering, friends lovingly uplift each other for the sake of our humanity. Maybe Bill James merits some of that love, too.

The views expressed in this column are those of the author and not necessarily those of The Observer.

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Kramer: Oh, the humanity! - Observer Online

One of the best young linebackers in the NFL is Darius Leonard, the third-year star for the Indianapolis Colts. He has ultimately become one of the best players in the entire league very quickly and one of its best tacklers. Leonard, however, recently called out the NFL after taking multiple drug tests within the past month.

RELATED: Philip Rivers Reveals How He Found Out About Andrew Lucks Shocking Retirement

In college, Leonard didnt play at a big school like Ohio State, Alabama, or Clemson. He played at South Carolina State but had a lot of success there.

He ultimately earned two MEAC Defensive Player of the Year awards as he led his team in tackles in three separate seasons. Additionally, in 10 games in 2017, Leonard had 113 total tackles, eight sacks, two interceptions, and one forced fumble, according to South Carolina States team site.

His play led to the Indianapolis Colts selecting him in the second round of the 2018 NFL draft. He has since become an absolute star.

In his rookie season, Leonard led the NFL in total tackles with 163, and in solo tackles with 111. He also had seven sacks, four forced fumbles, and two interceptions. Leonard ultimately became the first player to rack up at least 125 tackles, seven sacks, and four forced fumbles in a season since Bryan Cox in 1992, according to Colts.com. This all led to Leonard earning First-Team All-Pro honors and the AP Defensive Rookie of the Year award.

During the 2019 season, Leonard continued to become a top linebacker in the NFL. In 13 games, he racked up 121 total tackles, five sacks, two forced fumbles, and five interceptions. His five picks led all linebackers and tied for fourth-most in the NFL. Leonard earned Pro Bowl honors that season too.

RELATED: What Has Andrew Luck Been up To in His First Full Year of Retirement?

Being a stellar linebacker, Leonard is, of course, a pretty muscular guy. Now, the NFL has apparently had him take three drug tests within the past month.

He ended up tweeting this at the league.

3 PEDs tests in one month, Leonard tweeted. Im just out here off of natural energy and athletic abilities! Cmon [NFL] Yall dont have to drug test me every week damn near.

Former Indianapolis Colts defensive back Darius Butler responded to Leonards tweet, saying, Comes w/ the territory.

Butler seems to understand that the NFL does this to players often, and over the years, there have been plenty of players to complain it.

RELATED: Former Indianapolis Colts Linebacker Edwin Jackson Tragically Died After Having a Breakout Season

Leonard is certainly not the first NFL player to complain about having to take multiple drug tests. He probably wont be the last either.

Former Colts punter Pat McAfee got drug tested after tweeting about 4/20, another time after making a big tackle, and again after a 67-yard punt.

I would have been offended if they didnt test me, McAfee said in 2016, according to ESPN. You average 59 yards a punt. If you dont get tested for that, youre kind of upset about it to be honest One time I drank Smartwater and thought I was going to fail for intelligence. Today I drank Propel (water). It was a good, smart, intelligent (sample) today.

According to CBS Sports, in 2018, safety Eric Reid returned to the field after going unsigned for the first quarter of the season. Then, after just his sixth game back on the field, he said that he had been drug tested five times since signing with the Carolina Panthers.

This is like the fifth time since Ive been here, Reid said, per CBS Sports. Theyre not going to catch me on anything.

Additionally, in 2019, running back LeVeon Bell tweeted at the NFL, also complaining about drug tests.

I done had 5 random HGH blood test in 10 weeks, Bell tweeted. [NFL] Im not doing another after today, whatever yall lookin for it obviously aint there & Im not about to keep allowing yall to stick me with those dirty a** needles. Find the players who really do that HGH BS & get off me.

It seems like that as long as there are NFL players on the field, a bunch of them will be getting randomly drug tested, and that some of those players wont be too happy about it.

Stats courtesy of Pro Football Reference

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Darius Leonard Just Called Out the NFL After Having To Take Multiple Drug Tests - Sportscasting

As per a report Market-research, the Human Growth Hormone (HGH) economy is likely to see a CAGR increase of XX% within the forecast period (2019-2029) and reach at a value of US$ at the ending of 2029. The macro economic and micro elements which are predicted to influence the trajectory of this market are examined from the market analysis that was presented.

Light onto the material throws Providers, vendors, manufacturers, and market participants at the value string of their industry that is Human Growth Hormone (HGH) . Whats more, its particular influence on the market and the political and economic scenarios of regions are discussed within the analysis.

Critical Details included from this record:

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Competitive Outlook

Light onto the throws Business prospects of players operating from the industry that is Human Growth Hormone (HGH) . The item pricing plans, marketing stations that were preferred and product portfolio of most players, and promote presence of every and every provider is contained in the title. The players comprise Business 4, Business two, Business 3, and Business.

Regional Assessment

The marketplace research that is introduced sheds light onto the Marketplace Scenario in numerous markets. Additionally, the effects of the governmental and regulatory policies to this market in every regions prospects is examined from the report.

Competitive landscape

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The report Suits the questions pertaining Into the Human Growth Hormone (HGH) economy:

Reasons Fact.MR Sticks out

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Human Growth Hormone (HGH) Market Growth and Future Prospects Analyzed 2018 to 2028 - Bulletin Line

The research study on Global Hormone Replacement Therapy market 2019 presents an extensive analysis of current Hormone Replacement Therapy market size, drivers, trends, opportunities, challenges, as well as key Hormone Replacement Therapy market segments. Further, it explains various definitions and classification of the Hormone Replacement Therapy industry, applications, and chain structure.In continuation of this data, the Hormone Replacement Therapy report covers various marketing strategies followed by key players and distributors. Also explains Hormone Replacement Therapy marketing channels, potential buyers and development history. The intent of global Hormone Replacement Therapy research report is to depict the information to the user regarding Hormone Replacement Therapy market forecast and dynamics for the upcoming years. The Hormone Replacement Therapy study lists the essential elements which influence the growth of Hormone Replacement Therapy industry. Long-term evaluation of the worldwide Hormone Replacement Therapy market share from diverse countries and regions is roofed within the Hormone Replacement Therapy report. Additionally, includes Hormone Replacement Therapy type wise and application wise consumption figures.

The Final Report will cover the impact analysis of COVID-19 on this industry.

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After the basic information, the global Hormone Replacement Therapy Market study sheds light on the Hormone Replacement Therapy technological evolution, tie-ups, acquisition, innovative Hormone Replacement Therapy business approach, new launches and Hormone Replacement Therapy revenue. In addition, the Hormone Replacement Therapy industry growth in distinct regions and Hormone Replacement Therapy R;D status are enclosed within the report.The Hormone Replacement Therapy study also incorporates new investment feasibility analysis of Hormone Replacement Therapy. Together with strategically analyzing the key micro markets, the report also focuses on industry-specific drivers, restraints, opportunities, and challenges in the Hormone Replacement Therapy market.

Global Hormone Replacement Therapy Market Segmentation 2019: Hormone Replacement TherapyThe study also classifies the entire Hormone Replacement Therapy market on basis of leading manufacturers, different types, various applications and diverse geographical regions. Overall Hormone Replacement Therapy market is characterized by the existence of well-known global and regional Hormone Replacement Therapy vendors. These established Hormone Replacement Therapy players have huge essential resources and funds for Hormone Replacement Therapy research as well as developmental activities. Also, the Hormone Replacement Therapy manufacturers focusing on the development of new Hormone Replacement Therapy technologies and feedstock. In fact, this will enhance the competitive scenario of the Hormone Replacement Therapy industry.

The Leading Players involved in global Hormone Replacement Therapy market are:

By Therapy Type (Human Growth Hormone (HGH) Replacement Therapy, Testosterone Replacement Therapy, Thyroid Replacement Therapy, Estrogen Replacement Therapy)

By Application (Growth Hormone Deficiency,Menopause, Hypothyroidism, Male Hypogonadism, and Others)

By Route of Administration (Oral, Parenteral, and Others)

By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) 

By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa )

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Worldwide Hormone Replacement Therapy Market Different Analysis:Competitors Review of Hormone Replacement Therapy Market: Report presents the competitive landscape scenario seen among top Hormone Replacement Therapy players, their company profile, revenue, sales, business tactics and forecast Hormone Replacement Therapy industry situations. Production Review of Hormone Replacement Therapy Market: It illustrates the production volume, capacity with respect to major Hormone Replacement Therapy regions, application, type, and the price. Sales Margin and Revenue Accumulation Review of Hormone Replacement Therapy Market: Eventually explains sales margin and revenue accumulation based on key regions, price, revenue, and Hormone Replacement Therapy target consumer. Supply and Demand Review of Hormone Replacement Therapy Market: Coupled with sales margin, the report depicts the supply and demand seen in major regions, among key players and for every Hormone Replacement Therapy product type. Also interprets the Hormone Replacement Therapy import/export scenario. Other key reviews of Hormone Replacement Therapy Market: Apart from the above information, correspondingly covers the company website, number of employees, contact details of major Hormone Replacement Therapy players, potential consumers and suppliers. Also, the strengths, opportunities, Hormone Replacement Therapy market driving forces and market restraints are studied in this report.

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Global Hormone Replacement Therapy Market Report Provides Comprehensive Analysis of Following: ; Hormone Replacement Therapy Market segments and sub-segments ; Industry size ; Hormone Replacement Therapy shares ; Hormone Replacement Therapy Market trends and dynamics ; Market Drivers and Hormone Replacement Therapy Opportunities ; Supply and demand of world Hormone Replacement Therapy industry ; Technological inventions in Hormone Replacement Therapy trade ; Hormone Replacement Therapy Marketing Channel Development Trend ; Global Hormone Replacement Therapy Industry Positioning ; Pricing and Brand Strategy ; Distributors/Traders List enclosed in Positioning Hormone Replacement Therapy Market.

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Hormone Replacement Therapy Market 2020-2029 / Growth, Emerging Trends And Forecast - The News Brok

U.S. Biologics License Application for TransCon hGH submitted to U.S. Food and Drug Administration for pediatric growth hormone deficiency

Approval of Paediatric Investigation Plan by European Medicines Agency clears path for filing Marketing Authorisation Application for TransCon hGH in Europe in third quarter

New data from the four-week, fixed dose, double-blind portion of PaTH Forwarddemonstrated statistically significant and clinically meaningful improvementsin SF-36 functional health and well being outcomes

Conference call today at 4:30 p.m. Eastern Time

COPENHAGEN, Denmark, Aug. 27, 2020 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND), a biopharmaceutical company that utilizes its innovative TransCon technologies to address unmet medical needs, today announced new data from PaTH Forward and financial results for the quarter ended June 30, 2020.

We are executing across the globe on all elements of our Vision 3x3, including preparation for the expected U.S. launch for TransCon hGH following submission of our Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) in June, and preparing to submit the Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) for TransCon hGH in Europe planned for third quarter, said Jan Mikkelsen, Ascendis Pharmas President and Chief Executive Officer.

Mr. Mikkelsen continued, Additionally, with todays data release, we have, for the first time in a randomized, double-blind, placebo-controlled trial, demonstrated that a therapy for hypoparathyroidism (HP) may have a significant impact on improving quality of life for people living with HP compared to the standard of care. Our new data showed that TransCon PTH demonstrated a statistically significant1 and clinically meaningful impact on the SF-36 Health Survey (SF-36), a quality of life assessment tool validated to measure functional health and well being compared to placebo.2 Analysis of these exploratory endpoints, combined with expected findings from our proprietary patient reported outcome instrument, called Hypoparathyroidism Patient Experience Scale (HPES), will support the emerging body of evidence that TransCon PTH may function as a hormone replacement therapy and make a meaningful difference in improving the lives of people with HP.

Corporate Highlights & Progress

Second Quarter 2020 Financial Results

For the second quarter, Ascendis Pharma reported a net loss of 94.9 million, or 1.97 per share (basic and diluted) compared to a net loss of 58.9 million, or 1.25 per share (basic and diluted) for the same period in 2019.

Revenue for the second quarter was 1.4 million compared to 3.2 million in the same quarter of 2019. The decrease was due to a lower amount of license and service revenue being recognized from the companys strategic investment in VISEN Pharmaceuticals.

Research and development (R&D) costs for the second quarter were 63.6 million compared to 43.8 million during the same period in 2019. Higher R&D costs in 2020 reflect an increase in personnel-related costs, overhead costs allocated to R&D, and the continued progress in development of the companys product candidates.

Selling, general and administrative (SG&A) expenses for the second quarter were 20.8 million compared to 11.0 million during the same period in 2019. The increase is primarily due to additional personnel-related costs, higher IT and other site costs, and continued build out of the companys commercial capabilities.

As of June 30, 2020, Ascendis Pharma had cash, cash equivalents and marketable securities totaling 471.6 million compared to 534.4 million as of March 31, 2020. As of June 30, 2020, Ascendis Pharma had 48,345,782 ordinary shares outstanding.

Conference Call and Webcast information

Ascendis Pharma will host a conference call and webcast today at 4:30 p.m. Eastern Time (ET) to discuss its second quarter 2020 financial results. Details include:

A live webcast of the conference call will be available on the Investors and News section of the Ascendis Pharma website at http://www.ascendispharma.com. A webcast replay will also be available on this website shortly after conclusion of the event for 30 days.

About Ascendis Pharmas Pipeline

Ascendis Pharma currently has three product candidates in clinical development in rare endocrine diseases:

Additionally, the company has established oncology as its second therapeutic area of focus and plans to submit an IND or similar in the fourth quarter of 2020 for TransCon TLR7/8 Agonist, the companys first oncology product candidate.

AboutAscendis Pharma A/S

Ascendis Pharmais applying its innovative platform technology to build a leading, fully integrated biopharma company focused on making a meaningful difference in patients lives. Guided by its core values of patients, science and passion, the company utilizes its TransCon technologies to create new and potentially best-in-class therapies.

Ascendis Pharmacurrently has a pipeline of three independent endocrinology rare disease product candidates in clinical development and is advancing oncology as its second therapeutic area of focus. The company continues to expand into additional therapeutic areas to address unmet patient needs.

Ascendis is headquartered inCopenhagen, Denmark, with additional offices in Heidelberg andBerlin, Germany, and inPalo AltoandRedwood City, California.

Forward-Looking Statements

This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, included in this press release regarding Ascendis future operations, plans and objectives of management are forward-looking statements. Examples of such statements include, but are not limited to, statements relating to (i) Ascendis plans to submit its marketing application for TransCon hGH in in Europe in the third quarter of 2020, (ii) Ascendis plans to report six-month data from the open-label extension portion of the PaTH Forward Trial during the third quarter of 2020, (iii) Ascendis plans to submit regulatory filings to initiate a global phase 3 trial evaluating TransCon PTH in North America, Europe and Asia in the fourth quarter of 2020, (iv) Ascendis ability to apply its platform technology to build a leading, fully integrated biopharma company, (v) Ascendis product pipeline and expansion into additional therapeutic areas, and (vi) Ascendis expectations regarding its ability to utilize its TransCon technologies to create new and potentially best-in-class therapies. Ascendis may not actually achieve the plans, carry out the intentions or meet the expectations or projections disclosed in the forward-looking statements and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions, expectations and projections disclosed in the forward-looking statements. Various important factors could cause actual results or events to differ materially from the forward-looking statements that Ascendis makes, including the following: unforeseen safety or efficacy results in its oncology programs, TransCon hGH, TransCon PTH and TransCon CNP or other development programs; unforeseen expenses related to the development and potential commercialization of its oncology programs, TransCon hGH, TransCon PTH and TransCon CNP or other development programs, selling, general and administrative expenses, other research and development expenses and Ascendis business generally; delays in the development of its oncology programs, TransCon hGH, TransCon PTH and TransCon CNP or other development programs related to manufacturing, regulatory requirements, speed of patient recruitment or other unforeseen delays; dependence on third party manufacturers to supply study drug for planned clinical studies; Ascendis ability to obtain additional funding, if needed, to support its business activities and the effects on its business of the worldwide COVID-19 pandemic. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to Ascendis business in general, see Ascendis prospectus supplement filed onJuly 9, 2020and Ascendis current and future reports filed with, or submitted to, theU.S. Securities and Exchange Commission(SEC), including its Annual Report on Form 20-F filed with theSEConApril 3, 2020. Forward-looking statements do not reflect the potential impact of any future in-licensing, collaborations, acquisitions, mergers, dispositions, joint ventures, or investments that Ascendis may enter into or make. Ascendis does not assume any obligation to update any forward-looking statements, except as required by law.

Ascendis,Ascendis Pharma, theAscendis Pharmalogo, the company logo and TransCon are registered trademarks owned by theAscendis Pharma Group. August 2020Ascendis Pharma A/S.

FINANCIAL TABLES FOLLOW

____________1 Data on file.2 Maruish, M. E. (Ed.). Users manual for the SF-36v2 Health Survey (3rd ed.). Lincoln, RI: QualityMetric Incorporated.3 Horton WA, et al.Lancet. 2007;370(9582):162172.4 D.B. Rosen, et al. Poster presented at the American Association of Cancer Research (AACR) 2020 Virtual Annual Meeting II, June 2224 (virtual).5 Pauli RM. J Rare Dis. 2019; 14:1

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Ascendis Pharma A/S Reports Second Quarter 2020 Financial Results and Announces New Data from the Four-Week, Fixed Dose, Double-Blind Portion of the...

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