Search Weight Loss Topics:


Page 20«..10..19202122..3040..»


Oct 5

Nasonville fire annual, Fall parks programs: Five things to know in Burrillville this week – NRI NOW

On call plow driver wanted

The town of Burrillville is now accepting applications for an on call seasonal snow plow driver. The temporary position requires experience and pays $20 per hour. Application forms can be obtained at Town Hall and returned to the town managers office.

View the complete notice from the town here.

Women on Target

If you havent caught Wallum Lake Rod & Gun Clubs ongoing instructional shooting program for women, there are still tickets available for the final date remaining this season. The $45 program includes a classroom presentation and safety briefing followed by live firing under the direction of an instructor. Classes typically sell out, and the final date this season is Saturday, Nov. 20 from 9 a.m. to 2 p.m. Learn more or register here.

Parks programs

The Burrillville Parks & Recreation Department has announced a full lineup of classes and programs being offered this fall, including free classes for seniors at the Lodge beginning the week of October 18, along with ongoing sports and exercise classes. View the full schedule here.

Two tenors

Wei En Chan, countertenor and David Rivera Bozon, tenor Leona Cheung and piano will perform music of Mozart & Haydn at Grace Note Farm on Sunday, Oct. 10 from 2 to 4 p.m. Weather permitting, audience members can bring a picnic lunch to enjoy outdoors, walk the picturesque farm trails and view the farm animals prior to the concert.

Tickets cost $30 and all proceeds go to the artists. Call (401) 567-0354 for reservations and information.

Town meetings

The Burrillville Planning Board will hold a meeting on Monday, Oct. 4 starting at 7 p.m. at the Wallace F. Lees Safety Complex at 1477 Victory Highway. The agenda can be found here.

The Pascoag Fire District Board of Commissioners will hold a meeting on Tuesday, Oct. 5 starting at 6 p.m. at 141 Howard Ave. The agenda can be found here.

The Nasonville Fire District will hold its annual meeting on Tuesday, Oct. 5 starting at 7 p.m. at 2577 Victory Highway. The notice and warrant can be found here.

Read the original post:
Nasonville fire annual, Fall parks programs: Five things to know in Burrillville this week - NRI NOW


Oct 5

Effect of the COVID-19 pandemic on the physical and psychoaffective health of older adults in a physical exercise program – DocWire News

This article was originally published here

Exp Gerontol. 2021 Sep 30:111580. doi: 10.1016/j.exger.2021.111580. Online ahead of print.

ABSTRACT

COVID-19 lockdowns restricted physical activity levels for individuals in many countries. In particular, older adults experienced limited access to their usual activities, including physical exercise programs. How such restrictions and interruptions in physical exercise programs might impact the physical and mental health of older adults has not yet been studied. We sought to analyse changes in the physical and mental health of older adults enrolled in a group-based multicomponent physical exercise (MPE) program that was interrupted due to the COVID-19 pandemic. We followed 17 participants of this program from October 2018 to October 2020, including the interruption of the program during the pandemic. The MPE program included strength, balance, and stretching exercises. We compared anthropometric and cardiovascular parameters, physical fitness, frailty, quality of life, and psychoaffective status of participants before and during the COVID-19 pandemic. Most parameters followed the same pattern, improving after 8 months of the first MPE season (Oct. 2018-Jun. 2019), worsening after 4 months of summer rest, improving from October 2019 to January 2020 in the second MPE season (Oct. 2019-Jan. 2020), and severely worsening after 7 months of program interruption. We show that an MPE program has clear benefits to the physical and psychoaffective health of older adults, and interruption of these programs could adversely impact participants. These results highlight the need to maintain physical exercise programs or facilitate engagement in physical activity and reduce sedentary behaviour in older adults, particularly in situations such as the COVID-19 pandemic.

PMID:34601075 | DOI:10.1016/j.exger.2021.111580

See the article here:
Effect of the COVID-19 pandemic on the physical and psychoaffective health of older adults in a physical exercise program - DocWire News


Oct 5

Things that changed once I started eating intuitively – Daily Californian

Trigger warning: Disordered eating

As a former bulimic, my past relationship with food was certainly not the best. These days its hard to stay sane about food and not get sucked into the whirlwind of diet culture, especially as a college student. Our society places a heavy emphasis on weight and being thin, resulting in the mass production and dissemination of crash diets, diet pills, exercise programs, detox teas and calorie counting apps on the market.

I got stuck in the hamster wheel of diet culture; counting every calorie, tracking every macro and restricting my intake only to end up binging later on. Amid my eating disorder, I fell out of tune with my natural hunger cues, thus losing trust in my body and feeling more out of control than ever. Such a cycle harmed me physically, mentally and emotionally.

One of the biggest factors behind my recovery journey was learning to eat intuitively. Intuitive eating is simply about regaining your natural hunger and satiety cues, thereby eating in a way that best supports your physical and mental well-being. Rather than focusing on dieting to lose weight, intuitive eating is all about creating a healthy, nourishing and trusting relationship with food. As an intuitive eater, I dont attach a moral label to food, but see food as a neutral energy source. I dont demonize any food group and honor my cravings. I reject the tenets of diet culture and simply listen to my bodys biological responses to tell me when to eat and when to stop.

Anyone can become an intuitive eater. None of us were born with the innate knowledge of knowing how to use My Fitness Pal, rather, we were born with perfectly calibrated hunger and fullness cues. Through the course of our lifetimes, certain traumas, conditions or events may cause us to fall out of sync with our innate biological responses, but its never too late to regain them. Here are the biggest changes that left a positive impact once I decided to embark on my intuitive eating journey and ditch diet culture once and for all.

I stopped binging

A common misconception chronic dieters may have that prevents them from trying out intuitive eating is that theyll simply eat everything in sight. While you may initially eat more than normal when you first start eating intuitively, ultimately your body will balance out and relearn your hunger cues, resulting in you settling at the optimal healthy body weight for you.

Before intuitive eating, I refused to let a morsel of any food I deemed bad pass through my lips. Fried foods, processed foods, pastries, cake, cookies, chocolate and ice cream were all strictly off-limits. In addition to restricting certain types of foods, I restricted my caloric intake to a number that was too low for my body to meet its energy needs. This set the stage for immense cravings and late-night binge eating. When I started intuitive eating, I no longer demonized foods or restricted my calories, choosing to honor my cravings and my bodys wants. If I craved a cookie, I allowed myself to have one. I was astonished to see that when I removed the black-and-white thinking, caloric restriction and simply listened to my body, I no longer wanted to eat the whole box of cookies, but felt content and happy with just one.

I stopped thinking about food 24/7

Religiously logging every calorie and tracking every macro onto My Fitness Pal put food at the forefront of my mind everyday. My mind was imprinted by the calculator dictating how many calories I had eaten so far and how many I had left. As I ate one meal, I was already planning the other. So much of my mental energy was directed towards planning my next meal that I didnt have the ability to think about other things, such as school, my relationships and enjoying the little moments of life. Through intuitive eating, I was able to free up the mental space that obsessions over food once occupied and dedicate my newfound energy and time to more productive things.

I became more mindful

At the core of learning how to be an intuitive eater is mindfulness. Especially when first starting out, practicing mindfulness during meal times is imperative to relearning and listening to your natural hunger signals. Savor and taste the flavors and textures of every bite of food that enters your mouth and take note of how it makes your body feel. Dont rush to finish your food, but eat slowly and revel in every bite! I know many of us have the habit of going on our phones when we eat, but try to eliminate all distractions so that you can accurately gauge when youre satiated and appreciate the food youre eating. Practicing mindfulness during meal teams helped me build a foundation for practicing mindfulness in all areas of my life. As a result, Ive learned how to manage stress better and deal with my anxiety more effectively.

I became more social

Prior to intuitive eating, I avoided social situations where I knew food was going to be involved. I hated the thought of other people preparing my food because I didnt know what was going to be in it, so I couldnt accurately log the nutrition information. This led me to feeling more isolated than ever as I distanced myself from friends and new potential connections. Many of our social interactions involve eating with others and food can be a mode through which we make memories and connect with one another. When I began intuitive eating, I found food freedom and rid myself of food fear. This helped me no longer be afraid of going to restaurants or social gatherings with food. Instead of obsessively thinking about the calories or macros, I could focus on enjoying the conversation and banter with those around me.

Healing your relationship with food is a hard thing to do, but its totally worth it. Though it may sound difficult and scary, the intuitive eating framework changed my life and I hope it can change yours too.

Contact Madeleine Lorie at [emailprotected].

Read the original post:
Things that changed once I started eating intuitively - Daily Californian


Oct 5

Bike the distance to Rutgers University in Road to Game Day fitness event – OSU – The Lantern

The RPAC will host four separate cycling sessions for its Road to Game Day event Friday. | Credit: Lantern file photo.

The Buckeyes are hitting the road again after three consecutive home games, but this time, students can join in on the road trip from campus.

To kick off Saturdays football game, the RPAC is hosting multiple sessions of the Road to Game Day cycling event Friday, where students work together to bike 530 miles the distance from Ohio State to Rutgers University.

Four separate cycling sessions will take place throughout the day at 12:30 p.m., 1:30 p.m., 2:45 p.m. and 4:30 p.m., according to the Recreational Sports website. All rides will occur in the RPAC Northwest Plaza, where exercise bicycles will be outdoors for students to participate.

Aliyah Valdez, a group fitness graduate assistant and second-year masters student in higher education and student affairs, said the purpose of the event is to build community and promote Group Fitness programs and services, while being outside and together.

What we do for special events comes from what students want, Valdez said, If we continue to offer these new and different things and students like it and its successful, then its something we can revisit again next fall.

Alice Ryan, group fitness manager, said about 30 RPAC employees are bringing the 40 bikes outside to prepare for the day of riding.

Its a big team effort for a big team ride, Ryan said.

Valdez said attendees will receive free rec sports-themed items, be entered in a raffle for a sweatshirt and can enjoy food, pictures and a photobooth after the ride.

Ryan said anyone in the university community can participate in the free event to build awareness of the fitness programs offered and root on the Buckeyes at Rutgers University this weekend.

Students can select and register for a time here.

See more here:
Bike the distance to Rutgers University in Road to Game Day fitness event - OSU - The Lantern


Oct 5

Events of Monday, October 4, 2021 – jtv.tv

Glammed Up Tutoring. Jackson College. Mentoring and Tutoring Initiative. Students who attend tutoring at the Center for Student Success or Multicultural Center for three hours per week will receive a FREE service from a licensed cosmetologist. Attend one hour per week, receive $5 off a service. Bert Walker Hall, Multicultural Center. 6 9 p.m. Details here.

Boos Center Active Aging Program. The City of Jackson presents Active Aging programs at the Boos Center, Loomis Park. Walk This Way: Self-led indoor/outdoor walking program: Boos Center/Loomis Park M/W/F 9:30 am 10:30 am. Movement Matters: A standing, no-impact exercise program to strengthen your heart, increase muscle strength and improve flexibility: M/W/F 9:30 am 10:20 am.Sit & Stay Fit, A seated exercise program to strengthen your heart, increase muscle strength and improve flexibility: M/W/F 10:40 am 11:30 am.

The Great Pumpkin Decorating Contest. Jackson District Library. Decorate a pumpkin as your favorite literary/book character! All ages are welcome to participate. To submit, send a photo of your pumpkin tomarketing@myjdl.comwith your name and phone number any time from October 1-25. All entries will be entered into a drawing for prizes including an Amazon gift card, movie tickets and a Meijer gift card. The winner will be announced on November 1 and entries will be displayed on JDLs Facebook page.

Craft Work: Braided Bracelets. Jackson District Library. 3 PM to 4 PM. During October, the teen-themed celebration, Teentober, is being honored by teaching teens new crafting skills. We will be providing materials that will teach a Japanese braiding technique, called Kumihimo, which involves hemp cord, a disk to place the cord on, and include optional beads to add to the bracelets. This program will teach teens some new crafting skills, and well provide other resources to showcase other crafts that teens can learn more about, should they like to learn more. Craft kits will be available at all JDL branches starting October 4, while supplies last. An instructional video will be available onJDLs Facebook pageandYouTube channel.

Tinkergarten Fall Class. Tinkergarten is created by experts and loved by children and their families! Its a weekly class that meets outdoors for an hour of nature-based play, insights to help you learn alongside your child, research-based benefits of nature, socialization, and learning that is child-led. Enroll today to be a part of this amazing community of parents and children! Our season will be emphasizing FOCUS to help children build executive functioning skills like self-regulation among other skills. We will meet at beautiful Watkins Lake State Park and County Preserve! Sign up athttp://www.tinkergarten.com

View original post here:
Events of Monday, October 4, 2021 - jtv.tv


Aug 17

Effect of a dietary and exercise intervention in women with overweight and obesity undergoing fertility treatments: protocol for a randomized…

This is a single-blinded randomized control trial testing the efficacy of a dietary and exercise intervention for women with overweight and obesity undergoing infertility treatment. Ethical approval was obtained from the UAMS Institutional Review Board (UAMS IRB-260113), version 10 of the protocol. This article follows the SPIRIT (Standard Protocol Items: Recommendations for International Trials) guidelines for reporting clinical trial protocols [25]. Table1 and Fig.1 detail the time schedule of enrollment, interventions, and assessments. Findings will be disseminated via peer-reviewed manuscripts and presentations at scientific conferences, at which time protocol amendments will be discussed.

Study Flow Chart. Protocol schematic diagram including informed consent, visits, randomization, intervention and control groups, fertility clinic procedures, and cross over design. AF&GA: Arkansas Fertility and Gynecology Associates, BMI: Body Mass Index

This multi-component intervention will be conducted primarily via telemedicine, thus the location will vary and may include places like the participants homes or a local gym. Participants will be undergoing fertility treatments at Arkansas Fertility and Gynecology Associates (AF&GA), which serves Arkansas and surrounding states. Data collection will take place within AF&GA and the Arkansas Childrens Nutrition Center (ACNC), both of which are located in Little Rock, Arkansas.

Criteria for study inclusion are women with a BMI between 25 and 45kg/m2, age of 21years or over, and planning to undergo in vitro fertility treatment. Participants reporting the following will be excluded from the study: pre-existing conditions (e.g. sexual transmitted diseases) that will affect the outcomes of the study as determined by the principal investigator; current use of recreational drugs, tobacco, nicotine, or alcohol; food allergies, food intolerances, or food preferences which would interfere with compliance to the meal plan; and contraindications to exercise or already meeting the Physical Activity Guidelines for Americans [8] (150min moderate activity/week or 75min of vigorous activity/week with resistance exercise on 2 or more days/week.

Recruitment of participants will be conducted by the AF&GA team using IRB-approved tools. Advertisements and information sheets will be distributed to eligible participants electing to undergo fertility treatments. Women who are interested in participating in the study can inform the AF&GA team, call the ACNC recruitment line, send an e-mail expressing their interest, or express their interest through the ACNC website. To establish eligibility for participation in the study, a standardized questionnaire will be administered by phone.

The informed consent process will educate potential participants about the research study through IRB-approved methods. Eligible participants will be contacted, and a copy of the informed consent will be provided to the participant prior to signing consent documents. A research team member will reach out to potential participants 2days prior to the scheduled visit to perform a COVID-19 screening and answer questions on the intervention components of the study. At the first visit, the research team will review all study procedures and the informed consent documents with the potential participant. Participants will be given sufficient time to review the consent form, ask questions, and receive clarification prior to signing any documents. If eligible and interested in enrollment, informed consent will be obtained from the participants and documented.

Women will be randomized, with computer generated randomization, to a standard of care group (N=60) and an intervention group (N=60). Due to the high incidence of obese women with Polycystic Ovarian Syndrome (1530%) [26], compared with other infertility diagnoses, women will first be classified into one of two strata based on the presence or absence of PCOS. Within each stratum, the proposed study will randomize the enrolled participants into either the intervention group (N=30) or the standard of care group (N=30). Thus, the potential for confounders of infertility, besides PCOS, should be equally distributed between the groups and not affecting the main outcome of interests. The study will have four experimental arms: PCOS-standard of care, PCOS-intervention, no PCOS-standard of care, no PCOS-intervention. Allocation will happen at the second visit (after consent and the collection of baseline measures) by providing the participant with an opaque, sealed envelope containing their allocation.

The intervention, combining an exercise and a dietary component along with the standard practice from AF&GA, will take place during the weeks leading up to oocyte retrieval and continue until 2 weeks after implantation. We expect the intervention to last 812weeks, depending on the participants specific fertility treatment plan.

The intervention will be delivered by trained research team members who will meet with participants twice weekly and serve as their health coach in order to track compliance and support adherence to the meal and exercise plan. This contact will occur via their preferred contact method (e.g., telephone, text messages, email, or using applications such as FaceTime). All interventionists will complete an intensive training on the intervention protocol and motivational interviewing techniques [9, 27]. They will be provided with detailed counselor guides to follow. Prior to conducting a coaching session with a participant, they will be required to be certified by one of the study investigators in providing both initial and subsequent intervention sessions. All sessions will be video or audio recorded; 15% of sessions will be randomly selected, reviewed, and scored on a fidelity rating scale to ensure that the protocol is being implemented as intended. Fidelity ratings will include building and maintaining rapport; discussion of daily meal plan adherence and compliance; discussion of weekly exercise adherence and compliance [28]; use of SMART goal setting techniques [29]; engagement with participant in problem solving as needed; and use of reflective listening, positive reinforcement, and summarizing techniques [30]. Feedback will be provided to the coach on every session reviewed.

The exercise intervention will be based on the Physical Activity Guidelines for Americans for exercise prescription (150min of moderate exercise per week and muscle strengthening exercises on two or more days per week). The exercise program will be customized to the participant and delivered using a web- and mobile-based application. The exercise program will be built for 8 to 12weeks, depending on study length, with increasing intensity of combined aerobic and resistance exercises over the course of the study. The goal is for participants to perform at least 3 routines per week at their desired location. Total session time may vary by participants depending on number of breaks and rest periods. Exercise routines will combine aerobic, resistance and stretching exercises. In addition, participants will be encouraged to walk daily and increase their daily steps by 500 steps per day every week until they reach 10,000 steps per day. They will be able to monitor their steps with provided pedometers (Fitbit, Garmin, Apple Watch, etc.). Participants adherence to their exercise prescription and walking goal will be assessed weekly by the coach.

The dietary intervention is based on the Mediterranean diet. The meal plan was designed by a Registered Dietitian and follows the 2015 Dietary Guidelines for Americans healthy Mediterranean-style eating pattern (Tables2 and 3) [31]. Participants will be provided with all meals (3 meals/day) throughout the 812-week intervention that are in compliance with the Mediterranean diet in the form of refrigerated packaged meals from a company with the capacity to provide made-to-order meals and deliver them to the participants home address. The meals will be heated using conventional equipment found in most households and require no further preparation. Depending on calorie and macronutrient requirements, as assessed by the coach in accordance with participant feedback, snacks that adhere to the Mediterranean meal plan may be added. Snacks will include nutrient dense foods such as whole grains, fruits, nuts, low-fat milk, yogurt, and/or cheese. This nutrition intervention is not designed for participants to lose weight, however with the meal plan that could occur. Participants will be provided with a detailed weekly meal plan and will be asked to keep record of what they eat daily, on paper and/or using RedCap surveys.

Participants in the standard of care group will be provided with dietary and physical activity recommendations from the Dietary Guidelines for Americans at their first study visit and will follow the standard of care practice at AF&GA up to their retrieval procedures. Participants will not be required to wait 8weeks prior to their retrieval procedures since no intervention is needed. If participants in the standard of care group plan to undergo a second oocyte retrieval cycle, they will be offered to join the intervention group at that time as a cross over design.

Participants will be compensated for their time spent at the research facility, their traveling costs and efforts with a monetary value of $50 per visit. Participants randomized to the intervention group will also receive all free meals for a period of 8 to 12weeks depending on their fertility treatment plan. They will also receive training assistance, coaching, and reimbursement for monthly fees to a gym of their choice up to $50/month for the duration of the intervention. As an incentive to keep up with the exercise intervention, participants will be offered $10/week for meeting their step and exercise goal. A bonus of $80 will be provided to participants who completed all weekly exercise sessions prescribed. Participants in the standard of care group will receive a completion bonus with a monetary value of $200 at their last visit. Total compensation for the standard of care group (all paid by checks or gift cards) will be up to $350 dollars.

Participants will attend three research study visits at the ACNC, two at the beginning of their fertility procedures and the last within 5days of their oocyte retrieval procedures. Table 1 and Fig. 1 detail the time schedule of enrollment, participant visits, and the intervention. On average, we anticipate that there will be 812weeks between visit 1 and 3 depending on the participants fertility treatment plan. Questionnaires will be administered on paper or via online platforms such as RedCap.

Women who agree to participate will provide background information including their name, address, date of birth, education, number of people living in their household, marital status, and health history. Participants will be required to obtain an exercise release form from their physician at AF&GA prior to the study visit. They will also be required to sign a consent for release of medical information in order to obtain data relating to the clinical results from the fertility procedures as well as pregnancy and delivery outcomes.

Anthropometric data will include height, weight, and waist and hip circumferences. All measures will be repeated in duplicate or triplicate in order to ensure measures fall within stated tolerance ranges. Height will be measured to the nearest 0.1cm with a wall-mounted stadiometer (tolerance of +/1cm). Weight will be measured to the nearest 0.1kg on a scale that has been tared with clothing the participant is wearing (tolerance of +/0.1kg). Waist and hip circumferences will be measured to the nearest 0.1cm using a tape measure against bare skin or form fitted shorts (tolerance of +/1cm).

Vitals will include blood pressure, pulse, and temperature. Blood pressure and pulse will be measured with a digital blood pressure monitor twice (with 5min in between each measurement); a third measurement will be taken if the two measures have a difference of 6mmHg for systolic or 4mmHg for diastolic blood pressure. Temperature will be taken upon arrival for each visit with an infrared non-contact forehead thermometer in accordance with COVID-19 screening procedures. Participants with a temperature100.4F will be asked to reschedule their visit while those with a temperature below 100.4F will have it taken again orally with a SureTemp Plus thermometer for data collection purposes.

Body composition and bone mineral content will be measured using dual energy X-ray absorptiometry (DXA; Hologic Horizon A, Bedford, MA). This technology involves very small amounts of radiation and yields a very important measure of body composition and bone mineralization [32]. Quality control calibrations will be performed each day and subjects will be positioned according to the manufacturer recommendations for the whole body scan while wearing light clothing without metal.

Resting energy expenditure will be measured using indirect calorimetry (MOXUS, AEI technologies, IL) following an overnight fast while wearing a heart rate monitor (Polar, Finland) [33]. The instrument measures the flow of oxygen consumed and the flow of carbon dioxide produced to calculate energy expenditure. The system will be calibrated daily. Activity energy expenditure will be assessed using the ActiGraph9XLink accelerometer (ActiGraph, Pensacola, FL) worn for 7days and a previously validated physical activity questionnaire (International Physical Activity Questionnaire) [34].

A cardiorespiratory fitness test will be performed on a treadmill following the guidelines for exercise testing from the American College of Sports Medicine. After evaluating the participant at rest and during the 35min warm up, speed and/or incline will be increased in periods until exhaustion. During the entire test, breath composition will be sampled and measured using a metabolic cart (Medgraphics Ultima PFX system, MGC Diagnostics Corporation, St. Paul, MN, USA). Leg strength will be measured by an isokinetic dynamometer (Humac Norm, Computer Sports Medicine Inc., Stoughton, MA). The Humac dynamometer will be used for testing of right and left legs for flexion (hamstrings) and extension (quadriceps) at certain angular velocities.

Blood samples, up to 35ml, will be collected from the participants at visits 1 and 3 by a trained phlebotomist under overnight fasted conditions. During the entire study, we will collect up to 70ml total. Blood samples will be centrifuged to separate plasma, serum, and red blood cells. Blood samples will be used to assess glucose, insulin, HOMA-insulin resistance score, interleukin-6, C-Reactive Protein, tumor necrosis factor, leptin, lipid profiles or any other biomarkers or analytes of interest using ELISA, electrochemiluminescence (ECL), colorimetric assays, metabolomics or any other appropriate methodology. Urine and stool collection will be obtained to evaluate metabolites, hormones or bacteria/microbes. Samples will be obtained using sterile collection cups. All biological samples will be aliquoted and stored at 80C until further analyses.

Maternal depression will be evaluated using the Beck Depression Inventory-II, which has been shown to have high reliability and validity [35]. Participants level of perceived stress will be evaluated through the administration of the Cohens Perceived Stress Scale which is a validated 14-item questionnaire examining the perception of stressful life events and levels of experienced stress over the course of the 4 weeks prior to the completion of the survey [36]. Participants with elevated scores will be provided with mental health resources and referred to their primary care provider.

Baseline dietary intakes will be assessed using 3-day food records. Dietary data will be evaluated by a trained research assistant for completeness and analyzed with the Nutrition Data System for Research (NDSR, Nutrition Coordinating Center, University of Minnesota, MN). Data entry into this software will be randomly audited (10%) by a trained research assistant to ensure quality control.

AF&GA will provide the research team with oocytes (eggs), cumulus cells (cells surrounding the egg), and follicular fluid (liquid surrounding the egg that also contains granulosa cells) that are not needed for the IVF procedures (e.g., too many eggs retrieved). These samples will be collected during the standard oocyte retrieval procedures performed as part of standard care for the participants undergoing fertility treatment. Participants will undergo standard procedures at AF&GA for ovarian stimulation, which include hormonal superovulation and oocyte retrieval 36h after human gonadotropin injection. Any deviations from the standard clinic procedures will be documented and sensitivity analyses will be performed to determine whether deviations to stimulation protocol yielded in significant differences. It is possible that the research team will not obtain samples in the case that the retrieval yields only enough eggs for the IVF procedures. In this case, only follicular fluid will be obtained. The research team will not obtain samples that could have been fertilized or frozen as agreed with the participant prior to the retrieval procedure. The research team will obtain only samples that are unneeded by the clinic. Thus, no additional treatment or clinical procedures will be required for the participants. The embryologist at the clinic will collect the cumulus cells during the processing of the oocytes. Granulosa cells will be isolated from the follicular fluid by centrifugation at 4000rpm for 10min. Follicular fluid samples contaminated with blood will not be used for analysis. Samples will be placed on ice and transported by the research team to the ACNC where they will be stored in messenger RNA lysis buffer and frozen at 70C until processing. Oocytes and cumulus cells will be used to study gene expression while follicular fluid will be used to measure metabolites and hormones that may be influenced by diet and exercise. Both mRNA and genomic DNA will be isolated from individual oocytes as previously described [9]. cDNA libraries will be prepared and fragmented cDNA will be evaluated to determine size distribution of the libraries. Samples will be sequenced using the NextSeq 500 System (Illumina). Individual libraries will be generated and RNA-Seq will be conducted. Sequencing reads from each sample will be trimmed and filtered before being aligned to the human genome (hg19). All data will be analyzed using SeqMonk and R software. Differentially expressed gene expression will be identified using the DESeq2 package which will include multiple testing corrections. Serum and follicular fluid glucose, total cholesterol, and triglyceride levels will be assessed using colorimetric or electrochemiluminescence assays. Serum and follicular fluid insulin, leptin, tumor necrosis factor (TNF)-, C-reactive protein (CRP), and interleukin-6 will be measured using enzyme-linked immunosorbent or electrochemiluminescence assay kits. Serum lipid profilesnon-esterified fatty acids, high-density lipoprotein, and low-density lipoprotein will be analyzed by enzymatic methods on a clinical analyzer. All assays will be performed in accordance with the manufacturers instructions.

Feasibility and acceptability will be measured primarily through structured qualitative interviews that will take place after intervention completion. These interviews will be conducted by trained team members in-person or virtually through video conferencing and are expected to last approximately 60min. They will be audio recorded and transcribed before being coded and analyzed to identify key factors contributing to feasibility and acceptability of the intervention. Compliance with the intervention provides another measure of feasibility and acceptability. Participants in the intervention group will track their daily dietary intake for the duration of the intervention using paper and/or RedCap surveys. These surveys will be reviewed weekly by the health coach for completeness before being analyzed with NDSR (NDSR, Nutrition Coordinating Center, University of Minnesota, MN). To account for deviations from the meal plan, overall dietary compliance will be evaluated by comparing participants Healthy Eating Index (HEI) score to that of the standard meal plan. Participants will track their adherence to the exercise intervention (150min/wk. exercise) using personal training software (FitSW, FitSW Inc., Colorado Springs, CO) and their steps will be continuously monitored by a pedometer (Fitbit, Garmin, Apple Watch, etc.) provided by the research team. Compliance with the exercise prescription (150min/week) and walking goal (500 extra steps/week) will be assessed weekly by the health coach. Coaches will document the average number of weekly steps and total exercise minutes.

All investigators and research team members will complete and maintain appropriate CITI training. All data will be entered into the ACNC clinical relational database and/or RedCap. The database will be housed on a shared drive that is backed up nightly off-site Monday through Friday. Access to the server is password protected, as is access to the study database. Data and study samples will be labeled with a unique identifier (e.g., MB-101). This identifier will be in no way associated with the participants personal information, such as name or date of birth. The key to the coded information, all identifiers, and biological specimens will be destroyed 7years after the study close date. Data and samples will not be used for future research, either with or without identifiers. Participant names, contact information, and address will be shared with the meal preparation and delivery company. Data and samples will only be accessible by investigators, research assistants, and institutional oversight offices (e.g., IRB).

Prior to inferential analyses, exploratory data methods will be used to check for potential outliers and aberrant observations and measurements. The following will be tested between the PCOS and no PCOS groups to assess potential differences: fertility diagnosis (male factor, ovulatory disorder, tubal factor, endometriosis or unexplained), pregnancy, live birth, age and race using Mann-Whitney U nonparametric tests for each strata. Follicular fluid and serum metabolites will be analyzed using a one factor Analysis of Covariance (ANCOVA) at four levels because of the potential unbalanced data structure. Pair-wise comparisons using Tukey-Kramer post-hoc tests will be used to identify groups whose means differ significantly while retaining the family-wise error rate at 5%. If the distributional assumptions for ANOVA are not met, and if a suitable data transformation is not found, a Kruskal-Wallis equality-of-populations rank test will be used, followed by Dunns test of multiple comparisons. When the design is balanced, two-way ANOVA or non-parametric Friedman test will be used in data analysis. As alternatives, generalized linear models may be also used to test the effects of treatment and presence of PCOS and ANCOVA may also be used to control for additional confounding factors Correlations will be determined using the Pearson Product Moment or the Spearman Rank Order for non-parametric tests. Significance will be set at p<0.05. RNA-seq data will be analyzed using SeqMonk and R software. Gene expression levels will be expressed as raw read counts for differential expression analysis and as log-transformed normalized reads per kilobase per million mapped reads for visualization. Differentially expressed gene expression will be identified using the DESeq2 package and filtered at two-fold change and statistical significance with a p value 0.05. Gene Ontology (GO), transcription factor (TF) target analysis, and pathway analyses will be conducted with DAVID bioinformatics and/or WebGestalt, which include multiple testing corrections. For participants assigned to the standard of care whose fertility treatments were unsuccessful, they will be offered to re-enroll and be directly assigned to the intervention group. The data from these participants will be analyzed separately, using paired t-tests or non-parametric equivalent to evaluate the effect of the intervention (pre and post).

Based upon existing data in the literature, a power of 0.8, and a p-value set at 0.05, with 20 women per group, we will be able to detect a mean difference of at least 0.37 standard deviation units in follicular levels of C-reactive protein and of insulin. In our previous study, we found follicular fluid CRP differences of 3.2g/ml (2.7 vs. 5.9g/ml, respectively) between normal weight and obese women [12]. Thus, we are confident that this sample size will be sufficient to detect clinically meaningful differences. Based on our experience, we expect that we will be unsuccessful in obtaining a good quality oocyte from approximately 33% of women enrolled. Therefore, we will enroll 30 women in each of the 4 groups (PCOS- standard of care, PCOS-intervention, no PCOS- standard of care, no PCOS-intervention) to assure that we will have at least 20 oocytes per group.

A Data and Safety Monitoring Plan is in place for this study. Adverse events, enrollment numbers, lost to follow up counts, and withdrawals will be monitored by the Clinical Coordinator. A continuing review will also be completed annually. Any adverse events and deviations will be reported to the IRB and included in the continuing review. Any adverse effects or unanticipated problems will be reported to the study PI, the IRB, and the study sponsor in accordance with IRB policies. At all times, the IRB will be promptly provided with the information from the Clinical Coordinator as needed.

See the rest here:
Effect of a dietary and exercise intervention in women with overweight and obesity undergoing fertility treatments: protocol for a randomized...


Aug 17

How to quickly build muscle in your first 6 months of strength training, according to a powerlifter – Insider

Lifting weights might seem intimidating, but if you're new to strength training, you can put on muscle and gain strength faster than athletes with decades of experience.

That's the magic of "newbie gains," which refers to the extremely fast progress beginners can make in the first six months to a year of weightlifting or similar workouts. That's because your body isn't used to the new stimulus of working out and is primed to adapt quickly as a result, according to Chris Duffin, a world record-holding powerlifter and co-founder of Kabuki Strength.

With the right planning, you can make the most of "newbie gains" while they last, and set yourself up for long-term success. To optimize your training, Duffin recommends that you prioritize recovery, don't skimp on nutrition, stick to a specific workout routine, and avoid overtraining.

A morning gym session is fine, but not if you're getting less than adequate sleep as a result.One of the biggest mistakes you can make when starting a new workout routine is waking up too early to work out, according to Duffin.

Losing sleep to exercise is a common problem with gym newbies, he said, and can lead to more soreness and risk of injury. It can also defeat the purpose of strength training in the first place, since lack of sleep means you aren't giving your muscles time to grow and adapt, stalling your gains.

"It's like bending over to pick up a dime and missing the $10 bill in front of you. It doesn't make sense," Duffin said.

Most research recommends at least seven hours of sleep for the average adult, and up to nine or even ten hours for some elite athletes.

Another common mistake gym newbies make is what Duffin calls "shiny object syndrome" trying out many different workout programs in a short time, without spending much time on any of them.

"People are trying to find the secret sauce. They'll try an approach for a month and then hop to the next thing, but the only way you can learn what works for you is to stick with something," he said.

He recommends being consistent with a program for at least six months for best results.

Duffin said people often start a new fitness routine and a new diet at the same time, trying to change their body composition in the shortest amount of time.

But to build muscle effectively, you need to be in a calorie surplus, which means eating more food than you burn off in the form of exercise and daily activities. Cutting calories too much can slow muscle growth, worsen fatigue, and impair your progress on a new workout program.

To avoid missing out on gains, Duffin recommends changing one major variable in your routine at a time. For instance, if you're adding workout days or training more intensely, give your body time to adjust before making big tweaks to your diet.

Finally, while it can be tempting to go all-out on your fitness goals, Duffin said overtraining is a major barrier to progress.

"More is not better. You want to do the least amount to get the result you want," he said.

For fitness newbies, 45 minute workouts, three times a week is a good start.

Duffin said this slow, steady approach may take patience, but it's the best way to ensure the longevity of your gains.

"The beauty of strength training is that it continues to be progressive over time," he said.

Read this article:
How to quickly build muscle in your first 6 months of strength training, according to a powerlifter - Insider


Aug 17

Helping Southland Residents with Post-COVID Recovery – Los Angeles Business Journal

Some people who have had COVID-19 are finding their symptoms related to the virus continuing for many months. Shortness of breath, persistent fatigue, cognitive brain fog issues, difficulty eating and drinking, speech and language problems, cardiac issues, plus the anxiety or depression that can often be associated with the lengthy recovery from this new virus that we still have so much to learn about. It can affect almost every aspect of life and make resuming previous activities harder than expected.To combat the complicated, multi-layered process of post-COVID-19 recovery, Pomona Valley Hospital Medical Center (PVHMC) offers a comprehensive Post-COVID Recovery program designed to help those with post-COVID-19 health issues. Pulmonary rehabilitation-certified respiratory therapist, Tammy Magill, RRT, leads a highly skilled multidisciplinary therapy team who carefully evaluates symptoms, tests each patients underlying physiologic impairments, and individualizes a specific treatment plan based on the findings. The goal is to help patients recover from the continuing effects of the disease through specialized therapies and progressive exercise programs designed to improve lingering symptoms and restore functional independence as quickly and safely as possible. Interestingly, many of our Post-COVID Recovery patients were not necessarily the most ill, or those hospitalized the longest, said Magill. They managed their initial symptoms at home and, either never got over them completely, or got over them originally and symptoms returned months later.Alta Loma resident, Denalonor Bustamante, came to PVHMCs Emergency Department on December 9, 2021, where she was diagnosed with COVID-19, pneumonia and a sinus infection. She was admitted to the hospital, placed on high-flow oxygen and began her 22 day-stay in the Telemetry unit. She was discharged on New Years Eve and began the new year continuing her recovery at home.The first couple of weeks at home, I was weak and slept all the time. My head and body ached and I would cough nonstop for periods ranging from 45 minutes to 2 hours, said Denalonor. I had developed pulmonary thrombosis my doctor described it as taking shards of glass and spreading it on my lungs," Denalonor added.Denalonors pulmonologist, Dr. Rakesh Sinha, soon referred her to PVHMCs Post-COVID Recovery where she began twice weekly sessions on February 18, 2021. At her first appointment, they conducted an assessment she could only walk on the treadmill with no resistance for five minutes. She continued this five-minute rehab for the next 23 weeks and would come home so exhausted that she would sleep for 23 hours. A few months later and Denalonor can now walk on the treadmill with some resistance for more than 20 minutes. Im not as exhausted. My stamina is picking up and I am not coughing as much I can have a conversation now without gasping at every other word, said Denalonor. I fought long and hard in the hospital and had some dark days, but with the help of the amazing Post-COVID Recovery Associates, Im working on strengthening my lungs and I am hopeful.Patients who have completed the program say they are happy to be getting back to normal and report positive outcomes such as better breathing, improved oxygen levels, reduced anxiety levels, less fatigue, longer walk times, resuming previous recreational activities and returning to work.

For more information about PVHMCs Post-COVID Recovery Program, call (909) 865-9810 or visit

Return to Health Care Awards Pre-Event Supplement

For reprint and licensing requests for this article, CLICK HERE.

Follow this link:
Helping Southland Residents with Post-COVID Recovery - Los Angeles Business Journal


Aug 17

US Conducts Maritime Security Exercise in Gulf of Guinea with Allies – The Maritime Executive

Nigeria patrol boats participated in the exercises (US Navy photo)

PublishedAug 15, 2021 3:45 PM by The Maritime Executive

As part of its effort to demonstrate its commitment to maritime security in the Gulf of Guinea, U.S. forces conducted a series of exercises and a planning conference in the region. The efforts were in support of the global initiative and the programs being developed by the Nigerian government to combat the rise in assaults and hijackings of merchant ships in the region.

The Expeditionary Sea Base USS Hershel Woody Williams, which became the first warship permanently assigned to the U.S. Africa Command area of responsibility, lead the maritime security exercise. Also, participating were the Nigerian Navy, the Spanish Navy, and members of Ghanas Special Boat Squadron.

The exercises we conducted this week show our commitment to the mutual goal of countering maritime crimes in the Gulf of Guinea, and how we can work together to achieve it, said Capt. Chad Graham, commanding officer, USS Hershel Woody Williams. These maritime training operations required the collaboration of not one, but three countries navies, all working together simultaneously, said. Collaborative operations like this offer invaluable experience for my crew in the present, but they also allow us to be more efficient and capable in future operations with our partners in the region.

Officers of the Nigerian Navy touring the Williams (US Navy photo)

The three-day at sea training exercise consisted of maritime interdiction operations, visit, board, search, and seizure (VBSS) scenarios, fleet maneuvering, and helicopter insertion and casualty evacuations. Alongside Hershel Woody Williams, participating ships included Nigerian Navy ships NNS Prosperity, NNS Nguru, NNS Ekulu, NNS Osun, NNS Ose, and the Spanish Navy ship SPS Vigia, as well as the Nigerian Navys Regional Maritime Awareness Center at Western Naval Command.

This exercise followed a two-day maritime planning event held with leaders from the Nigerian Navy. Also, during the port visit in Logos, the crew of the Williams participated in a series of community relations activities, and the vessel hosted ship tours.

The program including a 3-day training exercise (U.S. Navy photo)

U.S. commanders noted that America shares a common interest with its African partner nations in ensuring security, safety, and freedom of navigation on the waters surrounding the continent. They noted that these waters are critical for Africas prosperity and access to global markets while recognizing that Gulf of Guinea nations have steadily increased their capability of working together and sharing information.

Nigeria maintains the largest navy in the Gulf of Guinea region. Recently, the government has initiated a concerted effort to increase security in the region. In July, Nigeria launched the Deep Blue Project, which is the first integrated maritime security strategy in West and Central Africa aimed at the ongoing threats of piracy and robbery. Nigeria is committing $195 million worth of new equipment along with a dedicated maritime security unit and training as part of the combined effort on land and at sea.

The U.S. joins with other members of the international community in an increased emphasis in providing greater maritime safety in the region. The Danish government announced plans to deploy a frigate to the area in the winter of 2021-2022 during the time when piracy activity typically increases. Denmark also called on other nations to join in deploying forces to the Gulf of Guinea.

The Williams is under the command of the U.S. Sixth Fleet, headquartered in Naples, Italy. As part of the ESB ship class, the U.S. Navy noted that she is a highly flexible platform that may be used across a broad range of military operations. Acting as a mobile sea base, the Williams is part of the critical access infrastructure that supports the deployment of forces and supplies to support missions.

See the original post:
US Conducts Maritime Security Exercise in Gulf of Guinea with Allies - The Maritime Executive


Aug 17

Wellbeats partners with M Health Fairview University of Minnesota Masonic Children’s Hospital to bring virtual wellness classes to patients and their…

ST. LOUIS PARK, Minn., Aug. 16, 2021 /PRNewswire-PRWeb/ --Hospital stays are stressful, and when a child is involved, it can be easy for parents to neglect their own health. Thanks to a new partnership between Wellbeats and M Health Fairview University of Minnesota Masonic Children's Hospital, families will have access to a free and convenient way to tend to their physical and emotional well-being while their children undergo treatment at the hospital.

The agreement, which took effect July 1, gives patients and families access to the more than 800 on-demand, virtual wellness classes in the Wellbeats app. This content is available free of charge to patients and families for the duration of their hospital stay. That means taking yoga or mindfulness classes from the comfort and privacy of a child's hospital room or participating in guided stretching exercises to work out the kinks from a night in a guest bed is all easily accessible to families. Whether an individual is looking for an intense workout to relieve stress or simply a quick break to get their blood flowing, Wellbeats delivers high-quality content for every age, ability level, and personal fitness preference.

"Wellness should be accessible and attainable to everyone, regardless of age, health status, or current life situation," said Jason Von Bank, president and CEO of Wellbeats. "We're proud to partner with Masonic Children's Hospital to enhance the exceptional care they provide with content that supports overall well-being and helps families maintain healthy habits during a time of great stress in their lives."

Wellbeats content isn't just for parents. With a wide range of classes tailored specifically to younger users, Masonic Children's Hospital patients can also access Wellbeats classes, as long as their health allows. All classes can be streamed with an internet-connected computer or on an iPhone or Android device through the Wellbeats app. Classes will also be available on televisions in patient rooms.

"Families may be with us for days or weeks at a time, so it's important to make their stay as comfortable as possible. With Wellbeats' on-demand content, families will have a diverse selection of engaging classes available any time of night or day, making it easy for them to be proactive about their well-being," said Jason Villar, service line strategy director for M Health Fairview University of Minnesota Masonic Children's Hospital. "We've already seen a positive response from patients and families to this offering and we look forward to the influence it will have on their experience with our hospital and their care. "

Wellbeats classes will be available to all families as long as the patient is undergoing inpatient or outpatient treatment at Masonic Children's Hospital.

To learn more about Wellbeats, visit Wellbeats.com.

####

About Wellbeats

Based in St. Louis Park, MN, Wellbeats is the premier provider of on-demand, virtual wellness content and programming for use in corporate well-being initiatives. With more than 800 exercise, nutrition, and mindfulness classes, challenges, and fitness assessments available anytime and anywhere, Wellbeats allows employers to support employees with wellness resources that fit their needs, lifestyle, and schedule. Wellbeats provides best-in-class content that appeals to people of all ages, interests, and fitness levels. Wellbeats content is easily accessible through apps for iOS, Android, Windows, and Apple TV; any modern Web browser, Chromecast, Airplay, and Roku. To learn more, visit http://www.wellbeats.com, Follow on LinkedIn or check out a sampling of the company's fitness classes during a Facebook Live session.

About M Health Fairview University of Minnesota Masonic Children's Hospital

M Health Fairview University of Minnesota Masonic Children's Hospital provides a broad range of more than 55 pediatric programs and specialties from surgery, imaging and neonatal and pediatric intensive care to cardiac and oncology services and blood and marrow and organ transplantation. Our clinical staff apply innovative approaches to creating medical breakthroughs based on their work with patients and on findings through research at the University of Minnesota. This has led to several firsts, including the first successful pediatric blood marrow transplant, infant heart transplant in Minnesota, and cochlear ear implant surgery for a child. Visit http://www.mhealthfairview.org to learn more.

Media Contact

Nathan Hansen, tabor PR, 612-414-0847, nathan@taborpr.com

SOURCE Wellbeats

Link:
Wellbeats partners with M Health Fairview University of Minnesota Masonic Children's Hospital to bring virtual wellness classes to patients and their...



Page 20«..10..19202122..3040..»