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Nov 8

Statins side effects: The worrisome sexual symptom men need to be aware of – Express

Statins are known to help keep cholesterol levels healthy further reducing the risk of heart attacks or strokes. As with most things, there are side effects which one needs to be aware of. Erectile dysfunction and lowered testosterone are some of the side effects reported. What is the link?

Statins are commonly prescribed to help lower cholesterol however, the drug also appears to lower testosterone.

According to a study which evaluated nearly 3,500 men who had erectile dysfunction, the drug could be the cause.

"Current statin therapy is associated with a twofold increased prevalence of hypogonadism a condition in which men don't produce enough testosterone, said Dr Giovanni Corona, lead study author and researcher at the University of Florence, Italy.

He added: "Our study is the first report showing a negative association between statin therapy and testosterone levels in a large series of patients consulting for sexual dysfunction.

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Dr Corona and colleagues evaluated 3,484 men, average age 51, who visited an outpatient clinic at the University of Florence with complaints of sexual dysfunction between January 2002 and August 2009.

Of that total, 244 (or seven percent) were being treated with statins for their high cholesterol.

The researchers calculated the men's total testosterone as well as free testosterone, and the amount of unbound testosterone in the bloodstream.

When they compared men on statins to those not, the men on statins were twice as likely to have low testosterone regardless of which of the three commonly used thresholds for low testosterone they looked at.

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Another study published in Oxford Academic investigated the lipid-lowering drug and its possible link to erectile dysfunction.

A systematic review was carried out using computerised biomedical databases and internet sources relating to erectile dysfunction and statins.

A significant literature was identified, much from obscure sources, which included case reports, review articles, and information from clinical trials and from regulatory agencies, noted the study.

It added: A substantial number of cases of erectile dysfunction associated with statin usage have been reported to regulatory agencies.

While erectile dysfunction isnt a widely reported side effect of statins, researchers have explored the possibility.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine you're taking.

It's run by a medicines safety watchdog called the Medicines and Healthcare products Regulatory Agency (MHRA).

The purpose of the scheme is to provide an early warning that the safety of a medicine or a medical device may require further investigation.

Side effects reported on Yellow Cards are evaluated, together with additional sources of information such as clinical trial data.

Excerpt from:
Statins side effects: The worrisome sexual symptom men need to be aware of - Express

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