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Sep 5

Why individuals put on weight as they age – Drew Reports News

Many people struggle to keep their weight in check as they age. Now brand-new research at Karolinska Institutet in Sweden has revealed why that is: Lipid turnover in the fat tissue reduces throughout ageing and makes it much easier to gain weight, even if we dont eat more or workout less than in the past. The research study is released in the journal Nature Medicine.

The scientists studied the fat cells in 54 males and females over a typical duration of 13 years. In that time, all subjects, despite whether they got or slimmed down, showed decreases in lipid turnover in the fat tissue, that is the rate at which lipid (or fat) in the fat cells is eliminated and kept. Those who didnt compensate for that by consuming less calories gained weight by approximately 20 percent, according to the study which was carried out in partnership with researchers at Uppsala University in Sweden and University of Lyon in France.

The scientists likewise took a look at lipid turnover in 41 ladies who underwent bariatric surgery and how the lipid turnover rate affected their capability to keep the weight off four to seven years after surgical treatment. The outcome revealed that only those who had a low rate prior to the surgery managed to increase their lipid turnover and keep their weight loss. The scientists believe these individuals might have had more space to increase their lipid turnover than those who already had a top-level pre-surgery.

The results indicate for the first time that processes in our fat tissue regulate changes in body weight during ageing in a way that is independent of other factors, says Peter Arner, professor at the Department of Medicine in Huddinge at Karolinska Institutet and one of the studys main authors. This could open up new ways to treat obesity.

Prior research studies have actually revealed that one way to accelerate the lipid turnover in the fat tissue is to work out more. This new research study supports that concept and further suggests that the long-term result of weight-loss surgery would enhance if combined with increased physical activity.

Obesity and obesity-related diseases have become a global problem, says Kirsty Spalding, senior researcher at the Department of Cell and Molecular Biology at Karolinska Institutet and another of the studys main authors. Understanding lipid dynamics and what regulates the size of the fat mass in humans has never been more relevant.

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Why individuals put on weight as they age - Drew Reports News

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