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Dec 30

Junk food affects the developing teen brain, promoting obesity. But its not hopeless. – The Philadelphia Inquirer

I am a neuroscientist and my research investigates how diet changes the brain. I want to understand how unhealthy diets impact the developing brain, and also why young people today are so prone to developing obesity.

Adolescents are the greatest consumers of calorie-rich junk foods. During puberty, many children have an insatiable appetite as rapid growth requires lots of energy. Heightened metabolism and growth spurts can protect against obesity, to an extent. But excessively eating high-calorie junk foods and increasingly sedentary lifestyles can outweigh any metabolic protection.

The teenage years are a key window of brain development. Adolescence coincides with a new-found social autonomy and the independence to make personal food choices.

During adolescence, connections between different brain regions and individual neurons are also being refined and strengthened. The adolescent brain is malleable because of increased levels of neuroplasticity.

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This means the brain is highly receptive to being shaped and rewired by the environment including diet. In turn, these changes can become hardwired when development is complete. So the adolescent brain is vulnerable to diet-induced changes, but these changes may endure through life.

Resisting junk food is tough

The prefrontal cortex controls and overrides urges triggered by events in the environment. Resisting eating a whole bag of candy or buying cheap junk foods can be particularly difficult for teenagers.

Voracious drive for rewards

Teenagers are particularly drawn to rewards, including sweet and calorie-dense foods. This is due to increased numbers of dopamine receptors in the adolescent brain, so the feeling of reward can be exaggerated. Frequent stimulation of the reward system results in enduring brain adaptations.

During adolescence, these changes may cause long-lasting shifts to the balance of brain chemicals.

Taken together, the teenage brain has a voracious drive for reward, diminished behavioral control and a susceptibility to be shaped by experience.

This manifests as a reduced ability to resist rewarding behaviors. So its not surprising that teenagers prefer to eat foods that are easy to obtain and immediately gratifying, even in the face of health advice to the contrary. But what are the enduring brain consequences?

Transcranial magnetic stimulation

Functional imaging studies show brain activity during tasks or viewing images of foods. Brain circuits that process food rewards are more active in adolescents with obesity compared to those considered normal weight.

Interestingly, lower activity is seen in regions of the prefrontal cortex. This shows that obesity can both heighten activation of the reward system and reduce brain activity in centers that can override the desire to eat.

Importantly, successful weight loss in adolescents restores levels of activity in the prefrontal cortex. This provides critical knowledge that the prefrontal cortex is a key area of the brain for controlling food intake, and that diet interventions increase activity in brain regions that exert self control.

Exercise boosts brain plasticity

Excessively eating junk foods during adolescence could alter brain development, leading to lasting poor diet habits. But, like a muscle, the brain can be exercised to improve willpower.

Increased brain plasticity during adolescence means the young mind may be more receptive to lifestyle changes. Physical exercise boosts brain plasticity, helping to set in place new healthy habits. Identifying how the brain is changed by obesity provides opportunities to identify and intervene.

Functional brain imaging adds a new layer of information where clinicians can identify at-risk individuals and track brain changes during nutritional and lifestyle interventions.

Even more, TMS could be a new treatment approach to improve re-calibration of the young brain to prevent enduring changes into adulthood.

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Junk food affects the developing teen brain, promoting obesity. But its not hopeless. - The Philadelphia Inquirer

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