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May 13

This startling discovery might protect men from coronavirus – BGR

With each day that goes by, we keep hearing of novel coronavirus therapies that can speed up recovery time and potentially reduce the risk of complications and death. It seems like doctors are throwing everything at the disease to see what sticks, but thats not exactly the case. Theyve simply had time to observe that some of the drugs that were created for other ailments can help COVID-19 patients as well. One such example is remdesivir, which was developed for Ebola but never used to treat it. Then theres the controversial hydroxychloroquine, a decades-old anti-malarial that can help some COVID-19 patients, but its not as effective and safe as people would have hoped. Anti-viral favipiravir (Avigan) was made for influenza but it might work on COVID-19 as well. And if this new study is right, a treatment thats usually given to prostate cancer patients could be used to protect men from the novel coronavirus.

Cancer is the kind of preexisting medical condition that might worsen the impact of the COVID-19 disease on patients. With that in mind, its not surprising that doctors paid close attention to their cohorts of cancer patients who were infected with the new virus. Researchers from Switzerland and Italy penned a new study that shows androgen-deprivation therapy (ADT) for prostate cancer would actually protect men from the novel coronavirus infection.

Published in the leading cancer journal Annals of Oncology, the study details this startling discovery. Researchers found that patients receiving ADT drugs were less likely to develop COVID-19, and the disease was less severe following an infection. The study says that out of 4,532 men in the Veneto region of Italy, 430 had cancer, with 118 of them having prostate cancer. Men with cancer had a 1.8x higher risk of COVID-19 infection compared to the male population without the ailment, and they developed a more severe form of the disease, the report says.

But when they looked at the entire population of prostate cancer patients in the Veneto region, they found that only four men out of 5,273 patients on ADT were infected with the novel coronavirus, and none of them died. Thats the kind of unusual statistical discrepancy that warrants more research.

37,161 men who have the same kind of cancer were treated with other therapies. Of those, 114 got COVID-19 and 18 died. Of the 79,661 patients with other types of cancer, 312 were infected, and 57 died.

The researchers now believe that men who do not have prostate cancer can be treated with ADT to either prevent COVID-19 symptoms or reduce the severity of the disease after infection.

I hope that our findings inspire other clinicians to carry out clinical trials using transient ADT in men infected with COVID-19, in addition to other experimental therapies, Swiss Universit della Svizzera Italiana professor Andrea Alimonti said. Although these data need to be further validated in additional large cohorts of patients with COVID-19, they provide an answer to the hypothesis that androgen levels can facilitate coronavirus infections and increase the severity of symptoms, as has been seen in male patients.

The Swiss and Italian researchers were motivated to look into this potential therapy following recent research that said a protein called TMPRSS2 from the family of Type II Transmembrane Serine Proteases could help the virus infect human cells. TMPRSS2 can be found in other places such as the lungs, which is where the novel coronavirus replicates the most, with potentially fatal consequences.

ADT drugs target androgen receptors, which regulate the high levels of TMPRSS2 in the prostate. Therefore, ADT can also regulate TMPRSS2 levels in the lungs and potentially reduce the viruss capability to infect cells. The ADT therapy would not last longer than a month and should have no significant side effects, Alimonti said. For instance, luteinizing hormone-releasing hormone, or LH-RH, antagonists can decrease the levels of testosterone in patients in 48 hours, and the effect of this therapy is transient. Once a patient stops taking the drug, his testosterone levels go back to the previous levels.

As with other coronavirus research, the cancer study will require additional research to see whether ADT drugs in COVID-19 patients who dont have cancer actually works. But the research doesnt only offer a potential treatment for men, it also explains why men might develop worse COVID-19 forms.

This could explain why men infected by COVID-19 develop a more aggressive form of disease than women, Alimonti said. It is known that ADT can decrease the levels of TMPRSS2 in prostate cancer patients, and some experimental evidence demonstrates that this could happen not only in the prostate but also in other tissues. So I wanted to see if ADT could decrease the risk of developing coronavirus infection in men with prostate cancer.

That may not be the sole explanation, as other studies show the virus does affect the testes directly. A recent study suggested that ACE2 receptors in the testicles explain why men are more likely than women to develop severe cases of COVID-19. Another report even showed that the virus can be present in semen, suggesting that sexual transmission could be a theoretical risk.

Image Source: Peter Foley/EPA-EFE/Shutterstock

Chris Smith started writing about gadgets as a hobby, and before he knew it he was sharing his views on tech stuff with readers around the world. Whenever he's not writing about gadgets he miserably fails to stay away from them, although he desperately tries. But that's not necessarily a bad thing.

Link:
This startling discovery might protect men from coronavirus - BGR


May 13

Top 10 supplements that should be used for men and women – The Jerusalem Post

Many natural medicines used by humanity over time are not recognized in actual days, supplements like Tribulus Terrestris, Maca Peruana, and Melatonin are very useful to provide a better lifestyle.Those supplements are natural and can improve sexual functions, metabolism, cognition, and response from the body to external conditions.

Some of those supplements were used by civilizations thousand years ago, in fact, when these herbs were used wasnt in supplement way, it was direct as plant most of the time in raw or crude ways

Here a list for you with some of those supplements that can help improve your body functions and make you live happier.

1 Peruvian Maca

This root was first used by people of Andes and was recognized worldwide by its functions related to sexual improvement from men and women, it can help women relieve symptoms of menopause and improve metabolism helping burn more fat during the day.

2 Tribulus Terrestris

Its another plant that is fully used flowers and leaves to improve libido, but it works in a different way, libido increased felling come from testosterone that is stimulated by Tribulus Terrestris, the metabolism get increased when levels of testosterone get normal. Fixing normal levels of testosterone many other benefits can be felt.

3 Melatonin

4 DHEA

DHEA is a hormone produced by the body thats responsible for many other hormones production that plays important functions on the body, hormones like testosterone get balanced when DHEA production is regulated after 30 DHEA levels get decreased and functions like muscle development get harder many other benefits come from hormonal balance, taking DHEA its a good way to fix all other hormone levels that was decreased by aging.

5 Lemon Essential Oil

6 Omega 3

Omega 3 provides many benefits, it plays important roles in the brain and can prevent many diseases like Alzheimer's, its recognized by an anti-inflammatory answer and can prevent most inflammatory diseases like cancer. It can be used to increase metabolism by decreasing fat resistance making it easier to be burned and protect the heart against bad fat.

7 Glucosamine and Chondroitin

Those 2 nutrients are fundamental to maintain the good health of joints, mainly when we get aged and need be on move, its hard to balance moves with joint resistance thats acquired over the time, glucosamine and chondroitin can help joint get lubricated and reduce pains.

8 Green Tea

Thats a very good antioxidant and as it is can be used to increase the immune system, in addition, it can also be used as a stimulant. Its caffeine content may help fat loss and some of the studies point it as a good joint protector.

9 Multivitamins

Its always hard to eat all foods that provide all vitamins and minerals spectrum, that way some of the supplements can be taken to provide all needings of your body, those supplements are not expensive and can make the bodywork better and improve metabolism during the day. Its not recommended to take it at night because probably it will make you go to the restroom.

10 BCAA ( Amino acids )

Amino acids are very important for muscle growth and to prevent it catabolism, in addition, it can also be used to increase the immune system. BCAA is showing very good effects on liver detox and restoring and can reduce fatigue from exercises.

That was our list of 10 best supplements that can help improve your life, any supplement can replace healthy habits, take care of your food, do exercises, drink water, breathe pure air, and use supplements wisely.

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Top 10 supplements that should be used for men and women - The Jerusalem Post


May 13

Androgen Replacement Therapy Market 2020 Coronavirus (Covid-19) Business Impact Future Forecast Assessed On The Basis Of How The Market Is Predicted…

The global Androgen Replacement Therapy Market research report thoroughly explains each and every aspect related to the Androgen Replacement Therapy Market, which facilitates the reports reader to study and evaluate the upcoming market trend and execute the analytical data to promote the business. The growth trend forecasted on account of thorough examination offers in-depth information regarding the global Androgen Replacement Therapy Market. A pathway of development is offered by the market to the several connected networks of businesses under it, which include different firms, industries, organizations, vendors, distributors, and local manufacturers too. All the key Androgen Replacement Therapy Market players compete with each other by offering better products and services at a reasonable price in order to grab significant share at the regional and global level market.

Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy, in which androgens, often testosterone, are replaced. ART is often prescribed to counter the effects of male hypogonadism. It typically involves the administration of testosterone through injections, skin creams, patches, gels, or subcutaneous pellets. Testosterone replacement therapy is a promising technology for improving symptoms of hypogonadism and to raise the testosterone level. Furthermore, benefits related to application of testosterone replacement therapy include an increase in muscle tissue, overall surge in energy, and significant decrease in depression symptoms.

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This report sample includesBrief Introduction to the research report.Table of Contents (Scope covered as a part of the study)Top players in the marketResearch framework (presentation)Research methodology adopted by Coherent Market Insights

The report incorporates an estimated impact of strict standards and regulations set by the government over the market in the upcoming years. The market report also comprises exhaustive research done using several analytical tools such as SWOT analysis to identify the market growth pattern.

Top Manufacturers in GlobalAndrogen Replacement TherapyMarket Includes:AbbVie, Inc., Allergan Plc, Bayer AG, Endo Pharmaceuticals, Inc., Eli Lilly and Company, Kyowa Kirin International Plc, Mylan N.V., Novartis International AG, Pfizer, Inc., Clarus Therapeutics, Ferring Holding SA, Perrigo Company Plc, Acerus Pharmaceuticals Corporation, Upsher-Smith Laboratories, LLC, Dr. Reddys Laboratories, Bausch Health Companies Inc., Sun Pharmaceutical Industries Ltd., and Par Pharmaceutical.

Regions & Countries Mentioned In The Androgen Replacement Therapy Market Report:

Key Highlights of the Table of Contents:

Androgen Replacement Therapy Market Study Coverage: It includes key manufacturers covered, key market segments, the scope of products offered in the global market, years considered, and study objectives. Furthermore, it tuches the segmentation study provided in the report on the basis of the type of product and applications.

Androgen Replacement Therapy Market Executive Summary: This section emphasizes on the key studies, market growth rate,Competitive landscape, market drivers, trends, and issues.

Androgen Replacement Therapy Market Production by Region: The report provides information related to import and export, production, revenue, and key players of all regional markets studied are covered in this section.

Androgen Replacement Therapy Market Profile of Manufacturers: Analysis of each market player profiled is detailed in this section. This also provides SWOT analysis, products, production, value, capacity, and other vital factors of the individual player.

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Table of Contents

Report Overview:It includes the Androgen Replacement Therapy market study scope, players covered, key market segments, market analysis by application, market analysis by type, and other chapters that give an overview of the research study.

Executive Summary:This section of the report gives information about Androgen Replacement Therapy market trends and shares, market size analysis by region and analysis of global market size. Under market size analysis by region, analysis of market share and growth rate by region is provided.

Profiles of International Players:Here, key players of the Androgen Replacement Therapy market are studied on the basis of gross margin, price, revenue, corporate sales, and production. This section gives a business overview of the players and shares their important company details.

Regional Study:All of the regions and countries analyzed in the Androgen Replacement Therapy market report is studied on the basis of market size by application, the market size by product, key players, and market forecast.

An Overview of the Impact of COVID-19 on this Market:

The pandemic of COVID-19 continues to expand and impact over 175 countries and territories. Although the outbreak appears to have slowed in China, COVID-19 has impacted globally. The pandemic could affect three main aspects of the global economy: production, supply chain, and firms and financial markets. National governments have announced largely uncoordinated, country-specific responses to the virus. As authorities encourage social distancing and consumers stay indoors, several businesses are hit. However, coherent, coordinated, and credible policy responses are expected to offer the best chance at limiting the economic fallout.

National governments and international bodies are focused on adopting collaborative efforts to encourage financial institutions to meet the financial needs of customers and members affected by the coronavirus. However, there are some sectors that have remained unscathed from the impact of the pandemic and there are some that are hit the hardest.

We, at Coherent Market Insights, understand the economic impact on various sectors and markets. Using our holistic market research methodology, we are focused on aiding your business sustain and grow during COVID-19 pandemics. With deep expertise across various industries-no matter how large or small- and with a team of highly experienced and dedicated analysts, Coherent Market Insights will offer you an impact analysis of coronavirus outbreak across industries to help you prepare for the future.

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Androgen Replacement Therapy Market 2020 Coronavirus (Covid-19) Business Impact Future Forecast Assessed On The Basis Of How The Market Is Predicted...


May 13

How DIM Supplements Work On Hormonal Acne, According To A Derm – Women’s Health

If youve suffered from hormonal acne, you know there's no easy fix. And yet, there's a supplement that's starting to garner attention for how well it seems to work. Diindolylmethane, or DIM, is a compound derived from cruciferous vegetables (think: broccoli, cauliflower, brussels sprouts, etc.)but if you cant get enough of it through your diet, it also comes in supplement form.

While it might seem too good to be true that a compound from green veggies could heal hormonal acne, some research indicates that it could even work as well as prescription medications. In fact, Morgan Rabach, MD, dermatologist and Co-Founder of LM Medical in NYC, says that it may work similarly to Spironolactone, a prescription drug dermatologists often recommend to treat hormonal acne.

Experts hypothesize that DIM may help balance hormones by blocking excess testosteroneand when hormones are balanced, hormonal breakouts should, in theory, be diminished. Lets back up a bit: When androgens (aka male hormones like testosterone) and hormone receptors (cells that translate messages to the body) bind together, it causes changes in the skin that can lead to acne.

Think of androgens binding to hormone receptors like a key in a lockthere is a cascade of effects that it unlocks when it happens, says Dr. Rabach. "This includes things like increased oil production in the face, which clogs the pores and leads to acne. In short, when androgens and hormone receptors interact, acne happens, but Spironolactone prevents that from ever happening to begin with.

DIM, as mentioned before, is thought to have the same mechanism as spironolactone. It binds to the androgen receptor so that there's no 'hole' for the androgen 'keys' to bind to," says Dr. Rabach. "When the the two cant bind, then oil isnt increased, and fewer clogged pores means less acne."

Because there is not yet solid data backing up these results or documenting clear dosages to recommend, Dr. Rabach says she's unlikely to recommend DIM in spite of the fact that, anecdotally, it works for many people.

"DIM shows promising results on hormonal acne in some people and may be a viable natural alternative for people that do not want traditional medicine, but there are no randomized placebo controlled studies, so I can't endorse it 100 percent," she says.

One other thing to note: The supplement industry isn't regulated, meaning the FDA doesn't vet products to make sure they contain exactly what they say they do. So, even if research indicated the dosage required for results (which it doesn't), it's hard to say for sure if you'd actually be getting that dosage from supplements you can buy in stores.

New York City-based publicist and blogger Stephanie OQuigley read about DIM online after finding herself lost for options on treating acne. Because it appeared every month at the same time and was mostly centered around her chin, Stephanie strongly suspected it was related to hormonesand no amount of clean pillowcases, salicylic acid or a dairy-free diet, was making a difference.

I started taking 200mg of DIMI'd read online that this was a great starting dose," she says. "After two to three months, I started to see results." After four months, her skin was pretty much clear. I didnt have to worry about waking up with a big whitehead on my chin," she says. "I would get the odd pimple, but for the most part, I felt great about my complexion.

For Stephanie, however, the good results ceased after seven months. There are so many factors that we dont know about each individual who takes DIM, like how is their diet, skin hygiene, stress, etc.," says Dr. Rabach. "One of those factors or a combination can override DIM." Unfortunately, it comes back to the same limitations on our knowledge of DIM's effectiveness and how it works: "There is no good research to explain how long or if DIM will work for everyone in a predictable way," says Dr. Rabach."

While there is no research-backed recommended dosage, anecdotally, some people say taking 100 milligrams twice a day has worked for themthough, of course, you should always consult your dermatologist or doctor before adding a new supplement to your regimen.

If you and your doctor do decide DIM is a good fit for you, Dr. Rabach says the most common side effects to be aware of are nausea, vomiting, bloating, diarrhea, gas, and headaches. It could also darken your urine due to the presence of DIM metabolites that have an amber color. "Individuals who eat large amounts of DIM-containing cruciferous vegetables would notice similarly colored urine," says naturopathic doctor Marcus Laux.

Bottom line: It may be worth a shotif your doctor approves.

While the hard-and-fast data and studies may not be there for DIM, the initial feedback from people who have used it is that it may work very similarly to Spironolactone. Plus, there are multiple personal success stories online. Sound like it might be a good fit for you? Be sure to have a conversation with your doctor first to determine whether it's safe.

Link:
How DIM Supplements Work On Hormonal Acne, According To A Derm - Women's Health


May 10

Outdoors: Theres more to turkeys necks than just color – Worcester Telegram

Wild turkeys displaying fields are thinning out as many of the recently fertilized females are now on their nests. Frustrated, polygamous males are walking farther to find the dwindling number of still-unfertilized, potential mates.

Exchanging my shotgun and crossbow for binoculars, I took the opportunity every morning this past week to closely observe the testosterone-driven males bizarre wattles that decorate their necks.

The red, white, and blue, naked, wrinkled and bulgy wattle skin isnt just a patriotic color combination. Its actually a very functional courting ornament for numerous species of male birds, including roosters and pheasants.

Wattles vary greatly. Large wattles correlate with peak maturity, high testosterone levels and good nutrition. They consequently advertise a sexy, healthy male and help turn on females. Young jakes have small, less impressive wattles.

During hot months, those highly vascularized pouches of skin, which are then predominantly white, can also help reflect and release heat. And now, when males are breeding, blood flow can engorge them so much in moments of excitement that they turn fire engine red for even greater sexual attraction. If I werent studying them to write about, Id be putting them on this weeks menu.

Successful turkey hunts have meant many delicious meals of supremely healthy meat that contains no man-injected hormones or anti-biotics that we find ubiquitous on our market shelves. And preparation is easy.

In quickly dressing their birds, many turkey hunters just fillet out the breasts. Most discard the highly tendinous, tough legs. But they shouldnt.

Those tough legs can be surprisingly delicious. I asked both my son and son-in-law, who were each successful in taking turkeys last week, to save their legs for me. Oakham bow hunter Rob Toupin taught me how cooking them and deer shanks in low heat for three to four hours in a crock pot will produce succulent, tender meat that can be easily pulled off the tendons. Dark meat is always more flavorful than white meat.

As for the breasts, its hard to top slicing off broad, thin pieces, then pounding them between wax paper to a uniform, pancake width, which allows for even, quick cooking. Just give them an egg wash, dip them in Panko, and saut them briefly in butter. Theres no simpler, quicker or more delicious way to serve them.

Turkey season continues through May 23. Forest walkers would be prudent to safely wear orange each morning till then.

Creatures of spring

This week, baby robins hatched, and mothers secretly carried away their shells and droppings. Red trilliums blossomed along with apple trees. Newly emergent, highly variable shades of young green thrilled our eyes.

Just as we were drawn outdoors by the high-70-degree temperatures, ants were drawn indoors, exploring countertops and floor board boundaries. Female mosquitoes searched for blood, and blackflies found many human faces to aggravate.

Sitting under a tree for a sundowner by our fire pit, I had several baby caterpillars and other insect larvae fall on me. No wonder the migrant songbirds from the jungles are returning en masse from the tropics.

To our regret, not all the caterpillars are good, though. Reader Pamela Shanley sent in photos of duct tape she just placed around her oak trees to protect them from gypsy moths, which are hatching on the ground right now and climbing up to eat fresh, tender, most nutritious baby leaves. While their population may be down this year, its worth killing every gypsy moth caterpillar we can. A single female can lay from 500-2,000 eggs.

Pamela annually wages war against them, even banding her neighbors together to fight the endless war. She recommends that this week we overlap three or four layers of duct tape around the trees inside out so the sticky part captures the instinctively climbing larvae. Once the tape is full of stuck caterpillars, Pamela applies new strips right over the used tape, which she totally removes from her trees in mid- to late June.

Here come shad

The number of shad passing over the Holyoke dam on the Connecticut River has been very impressive, considering how early the season is. Some 7,291 shad passed over on May 4 alone. Receding water levels helped that first passage last week, but rising flows over the wet weekend forced closure of the fish lift operations again. Interestingly, the COVID-19 challenge has resulted in the implementation of video counts.

The runs duration is much dependent on our weather. Shad will proceed upriver and drop their eggs in place wherever they are when water temperatures are about to get too warm. Its vital that males accompany the females all along their way to eject their sperm at the precise moment that the eggs are laid.

Plenty out fishing

The opening of Wachusett and Quabbin to shore fishermen was celebrated like Fourth of July. Reader Peter Bourneuf reported, Took a ride around the Rez yesterday. Must have been over 300 cars, trucks, and bikes over there. But the fishing has been great. Three- to 4-pound lake trout have been the main prize at Wachusett.

Over on the West River, size 14 black quills have been hatching out along with caddis to provide some excellent dry fly action.

Tuna limits adjusted

Big game recreational fishermen may be surprised to learn that NOAA adjusted the 2020 tuna daily limits. Private, permitted vessels are allowed two bluefin from 27 to less than 47 inches, and one 47 to less than 73 inches. Anglers can additionally catch and release or tag and release bluefin tuna of all size. Were counting on those latter anglers to be ethically responsible and handle those fish in a manner that will maximize their survivability without removing the fish from the water.

Permitted charter boats will now be able to take three school tuna (27-47 inches) and one large tuna 47-73 inches. Head or party boats will be able to take six school tuna and two large ones. Some local charter boat captains think this increased limit is too high and blame the vocal and politically influential charter boat lobby down south.

The commercial limits have yet to be set. Last year was a fiasco. The season opened with a three-fish-per-day limit, which almost instantly flooded the market. A knee-jerk reduction right afterward failed to heal the damage, and prices beneficial to fishermen never rebounded. Some captains would like to see opening week limits set at one fish per day and possibly adjusted sensibly afterwards.

Party and charter boat fishing may open May 18, if all goes best. Those first party boats with large capacities will be fishing mostly for scup and sea bass. They attract many outsiders from the bigger cities. As charter boat captain Bruce Peters shares, There really isnt an effective way to safe distance individuals on these boats. But small charter boats can be very different, and as such, may deserve differential treatment.

Most charter boat customers are families, workmates, and friends, already in close contact with each other," Peters claims. "Our charter boat takes six or fewer people, and are large enough to enable social distances. With masks, there is not a high-risk factor at all.

Peters is hoping that by June, restrictions will be more reasonable.

Good bass

On the striped bass front, cows up to 40 pounds have reached as far north as western Long Island Sound, and faster-moving schoolies already have invaded the New Hampshire coast. Although fluke season doesnt open here until May 23, its open now in New York, Rhode Island and Connecticut.

Lobster pots now

Since the last right whale mothers have taken their babies north out of Cape Cod Bay, lobstermen can now set their pots, and boaters can increase their speeds.

Have some fish

Meanwhile, as pork, chicken and beef supplies from outside our region become less reliable, this is a great time to patronize fish markets and support our local fishermen who can bring us the best fresh haddock, squid, shellfish, scallops, lobster, sea bass, mackerel, striped bass and fluke.

Contact Mark Blazis at markblazissafaris@gmail.com.

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Outdoors: Theres more to turkeys necks than just color - Worcester Telegram


May 10

Coronavirus: Men Are Twice As Likely To Die And The Reason Is Testosterone – Latin Times

With the recent reports observing the pattern of the coronavirus pandemic, it has been found that while infection rates between men and women are even, in comparison to women, more men die of COVID-19.

Professor Andrea Alimonti of the Universit della Svizzera Italiana-Switzerland said the reason is the presence of male sex hormone, testosterone, and those who are receiving androgen deprivation therapies (ADT) for prostate cancer are less likely to be infected.

ADT administered to patients of prostate cancer heightens their chances of not contracting coronavirus as compared to those who are not on ADT. This therapy is given to prostate cancer patients to reduce testosterone production or blocks its binding to receptors. It works on the observation that cancer cells thrive on male hormones and without its presence they starve, unable to multiply.

And as patients undergoing the treatment have shown less susceptibility to COVID-19, chances are that the reason males are more likely to die than females from the pandemic is the presence of testosterone.

Thetheory was further backed in the Annals of Oncology, by Prof. Alimonti that to date, patients of cancer, including prostate cancer, are at a higher risk of being diagnosed with COVID-19 in Italy's hard-hit Vento region as the disease lowers a bodys defenses.

He found that men with prostate cancer were 1.8 times likely to be diagnosed with COVID-19 as men who dont have cancer. But when the results were compared with the patients who were on ADT, it was found that while men with prostate cancer not on ADT, 0.31 infection rate, men undergoing ADT have a quarter of the mentioned infection rate.

We... have found that those being treated with ADT for prostate cancer are protected, even though all patients with cancer have a greater risk of Covid-19 infection than non-cancer patients, Alimonti said in a statement.

But, even though, Alimonti suggests that men, whether patients of prostate cancer or not, should be given temporary doses of ADT to men, especially those who have a higher risk of catching the virus and assured testosterone levels return to normal once ADT is stopped.

This is an Electron Microscopy of Coronavirus. Murphy Medical Associates

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Coronavirus: Men Are Twice As Likely To Die And The Reason Is Testosterone - Latin Times


May 10

Testosterone Replacement Therapy Market 2020 | Growth Drivers, Challenges, Trends, Market Dynamics and Forecast to 2026 – Cole of Duty

Acerus Pharmaceuticals

The scope of the Report:

The report analyzes the key opportunities, CAGR, and Y-o-Y growth rates to allow readers to understand all the qualitative and quantitative aspects of the Testosterone Replacement Therapy market. A competition analysis is imperative in the Testosterone Replacement Therapy market and the competition landscape serves this objective. A wide company overview, financials, recent developments, and long and short-term strategies adopted are par for the course. Various parameters have been taken into account while estimating market size. The revenue generated by the leading industry participants in the sales of Testosterone Replacement Therapy across the world has been calculated through primary and secondary research. The Testosterone Replacement Therapy Market analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status.

By Regions:

* North America (The US, Canada, and Mexico)

* Europe (Germany, France, the UK, and Rest of the World)

* Asia Pacific (China, Japan, India, and Rest of Asia Pacific)

* Latin America (Brazil and Rest of Latin America.)

* Middle East & Africa (Saudi Arabia, the UAE, , South Africa, and Rest of Middle East & Africa)

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Highlights of the Testosterone Replacement Therapy market study:

Speculations for sales:

The report contains historical revenue and volume that backing information about the market capacity, and it helps to evaluate conjecture numbers for key areas in the Testosterone Replacement Therapy market. Additionally, it includes a share of every segment of the Testosterone Replacement Therapy market, giving methodical information about types and applications of the market.

Key point summary of the Testosterone Replacement Therapy market report:

This report gives a forward-looking prospect of various factors driving or restraining market growth.

It presents an in-depth analysis of changing competition dynamics and puts you ahead of competitors.

It gives a six-year forecast evaluated on the basis of how the market is predicted to grow.

It assists in making informed business decisions by creating a pin-point analysis of market segments and by having complete insights of the Testosterone Replacement Therapy market.

This report helps users in comprehending the key product segments and their future.

Strategic Points Covered in TOC:

Chapter 1: Introduction, market driving force product scope, market risk, market overview, and market opportunities of the global Testosterone Replacement Therapy market

Chapter 2: Evaluating the leading manufacturers of the global Testosterone Replacement Therapy market which consists of its revenue, sales, and price of the products

Chapter 3: Displaying the competitive nature among key manufacturers, with market share, revenue, and sales

Chapter 4: Presenting global Testosterone Replacement Therapy market by regions, market share and with revenue and sales for the projected period

Chapter 5, 6, 7, 8 and 9: To evaluate the market by segments, by countries and by manufacturers with revenue share and sales by key countries in these various regions

Finally, the report global Testosterone Replacement Therapy market describes Testosterone Replacement Therapy industry expansion game plan, the Testosterone Replacement Therapy industry knowledge supply, appendix, analysis findings and the conclusion. It includes a through explanation of the cutting-edging technologies and investments being made to upgrade the existing ones.

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Testosterone Replacement Therapy Market 2020 | Growth Drivers, Challenges, Trends, Market Dynamics and Forecast to 2026 - Cole of Duty


May 10

Art House Extra: ‘The Road Warrior’ Will Rev Your Engine – Flatland

Art House Extra: 'The Road Warrior' Will Rev Your Engine Join our family of curious Kansas Citians

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Folks with an unquenchable thirst for dystopia need look no further than The Road Warrior, a testosterone-fueled chase movie set in a post-apocalyptic Australian outback.

Directed by George Miller and starring a young Mel Gibson, the movie speculates on a bleak future in which society has been destroyed and the only thing of real value is the fuel to keep your motor running. It all makes a certain sense, given the fact that the movie was created in the wake of a succession of oil crises.

Plausible or not, the movie set a new standard for high-speed action. Music buffs should also note that Queen guitarist Brian May did the soundtrack.

Let Art House host John McGrath take it from here in the attached video. Vroom, vroom

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Art House Extra: 'The Road Warrior' Will Rev Your Engine - Flatland


May 10

Coming to University and Into Their Own – NYU Washington Square News

Dear reader, here you will find three stories of transgender and genderqueer students from NYU. All of them embarked on separate journeys of self-discovery and self-acceptance once they found themselves in college. They faced various challenges along the way and preserved in their goal of living at their most authentic selves.

For August, attending NYU was a dream come true.

They had come out as transgender at the beginning of their high school career. NYUs location in Greenwich Village, a hub for the LGBTQ+ movement and home to the Stonewall Inn, presented an exciting experience suited for August.

New York, and NYU by proxy, associates with a queer-friendly climate. At the university, such an environment was created by the clubs and alliances run by and for LGBTQ+ students and staff members from all across the spectrum. Theres also a graduation ceremony that celebrates queer students and The Gender and Sexuality Team at the Student Health Center, helping transgender and gender-nonconforming individuals transition, explore their identities in a safer environment and live as their authentic selves.

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August, now a Steinhardt graduate, turned their tassel at Yankee Stadium last May. They had spent their last four years at NYU coming into themselves as an active member of NYUs LQBTQ+ community and the president of T-Party, a safe space on campus for TGNC individuals.

August saw NYU as their excuse to get as far as physically possible from LA, where they were stuck in an inhibiting home environment with their father, an avid conservative, and their mother, misinformed on LGBTQ+ issues. But, in preparation for the cross-country move, August had a difficult promise to keep.

[My parents] said I was going to NYU if I dont medically transition, August said. My tuition was on the line. I agreed. It was either go to my dream school or not go to my dream school.

With this, August left for New York. Regardless, they were excited for a change in the environment. But they never really intended on keeping their promise to their parents. They spent their first two years getting acclimated to college life, but the promise they made weighed heavy on their mind.

My dysphoria was getting worse, and I was going into such deep depression watching all of my friends transition, August said. Just knowing that there was this thing I could be doing for myself, but there was this arbitrary reason that I couldnt.

Junior year came and August pushed their fear of backlash from their family aside, concerned more with their own happiness and decided to start medically transitioning.

In preparation to medically transition, many transgender individuals decide to take either testosterone or estrogen to develop masculine or feminine traits, respectively, a procedure known as Hormone Replacement Therapy. After completing a blood test at the Student Health Center, it was determined that they were healthy enough to get on testosterone. Hormones can be taken in a variety of ways, including applying a hormone-induced gel on your shoulder or forearm and receiving intramuscular injections. August started taking hormones at the beginning of their junior year in the form of AndroGel gel pumps.

After Augusts parents found out through an insurance company notification, they took August off their insurance plan and presented an ultimatum: If August wanted to stay at NYU, they had to stop taking hormones. August refused and, eventually, their parents agreed to keep paying their tuition if they saw a therapist in the city.

After being on testosterone for nearly two years, August decided to get top surgery, a common type of gender-confirmation surgery which involves breast removal in order to create a masculine chest. With no medical insurance from their parents, August needed alternative payment methods to cover the surgery.Luckily for them, NYUs Consolidated Health Plan partially covered it. The rest came from Augusts GoFundMe, Augusts Transition Fund. Many things changed for August since their surgery, even their relationship with their parents improved.

Things are good between me and my parents right now, I think, August said with a smile. A lot of their transphobia is seeded in fear that me being trans will hinder me in some way. Its up to them to do the work on other people instead of working on me. Working on other people being comfortable with me.

With a coffee cup in her hand, Remy Elliott looks serene. Her saturated pink lipstick seems to be exactly the right shade to match her pale purple blouse. Her mouth forms a slight smile. When she talks, her voice is soft.

Steinhardt Masters in Childhood Education student Elliott publicly came out as transgender during her senior year in college. Elliott began by coming out to her close friends only. Feeling their acceptance of her authentic identity, she made an announcement on Facebook for International Womens Day in March of 2019, hoping to reach her hometown friends, acquaintances and distant family alike.

After years and years of careful thought and reflection, Im so happy to finally announce that I am transgender! Elliotts post reads. From here on out, Ill be living my life as the woman that Ive always been! Id like to be called by my real name, Remy, and not my deadname

Coming out later in her college career bore a lot of challenges for Elliott, externally and internally. While she began mentioning her struggle with her then-cis gender identity to friends around her sophomore year, coming out more publicly took time and seeking for validation from within. Elliott was worried she wasnt transgender enough.

For a long time, I was under the impression that I was trans but will never do anything about it, Elliott said. My dysphoria wasnt so bad that I felt like I was living a lie constantly. I could kind of make it through as a man.

But the pressure grew as the end of college approached. As a senior majoring in education, she had to have a teaching placement and was assigned to teach in a New York primary school last January.

Wishing to enter her new workplace as her real self, Elliott pushed herself to make a switch from masculine to feminine pronouns.

Contributing to the difficulties was the mismatch in the way Elliott felt and the way she was perceived from the outside. For many transgender individuals, theres a distinction between coming out and socially transitioning. For some, the two go hand-in-hand. For others, the choice to do one or the other can be more nuanced, involving difficult financial decisions, possible medical roadblocks including health conditions and considerations, lack of appropriate insurance coverage or potential judgement of those closest to the person. While social transitioning usually involves a name change, after which ones birth name becomes their deadname, and a pronouns switch, medical transitioning involves a multitude of procedures, including hormone replacement therapy and top or bottom surgeries.

Even with her determination to finally come out as a trans-woman, she found it difficult to navigate the resistance in her immediate community. The closest of her friends made the switch with no issues but the majority of the community around her struggled with misgendering and deadnaming Elliott.

Once I started going full-time [as a female] it got easier for people to come to terms with, Elliott said. When I was fluid, people had a harder time wrapping their heads around it.

After coming out, I didnt start transitioning immediately, Elliott said. I kept wearing masculine clothes and went by my deadname for a while.

Later in her senior year, Elliott began experimenting with her appearance, practicing different makeup techniques she enjoyed and building a more feminine wardrobe, discovering what clothes she felt most comfortable in. Towards the end of her senior year, Elliott chose to begin HRT and started taking estrogen with the intention of feminizing her appearance further. As an NYU student, she had Comprehensive Healthcare Plan insurance through Wellfleet, which covered the cost of her HRT.

For the Transgender Day of Visibility celebrated on March 31, Somaya Gupta posted a picture of themselves ready to shave, with the shaving cream on their face and a razor in their hand.

I have a distinct memory of being a kid and watching my dad shave his face and thinking that looks so fun, I wish I could do that, Gupta wrote in the caption. But growing up as a brown girl, I quickly learned that shaving my face was not acceptable One incredible lesson Ive learned through accepting my transness is that the instincts you had as a child were usually right

Gupta, who is graduating from Steinhardt this year, identifies as genderqueer and uses any pronouns. Despite being a senior, Gupta finds themselves in the process of still figuring out the labels they feel most comfortable with and where they fall on the gender spectrum.

At some point during their first year, Gupta and their then-roommate went to a friends dorm. The friend identifies as non-binary. On their way back, Guptas roommate asked what non-binary meant and Gupta explained, ultimately wondering how people ever realized their genderqueerness.

Does anyone ever feel like their gender? Gupta asked. You just say youre a girl because you were told that, right? But she was like no, you feel like a girl and so panic ensued.

In their sophomore year, Gupta, still silently questioning themselves but leaving the thoughts about their gender identity on the backburner, joined Shades, seeking a community of LGBTQ+ people of color who could relate to and understand their intersectional experience.

Throughout their time at NYU, theyve been involved with LGBTQ+ advocacy as the president of Shades LGBTQ+ Centers club for Black queer people and queer people of color and serves as a campus ambassador for GLAAD. While advocating for others, Gupta found themselves on their own journey of self-discovery and self-acceptance.

By their junior year, they had a lot of transgender and genderqueer friends, to whom they related a lot. This allowed them to begin self-discovery without the fear of losing their loved ones.

Junior year, when I came back from winter break, we had our first Shades meeting, Gupta said. We all go around and say our names and pronouns. And I said to everyone, when I usually said she and her, Im not sure so Ill just go with any pronouns. After I said that, a couple of people were like woo, thats cool!

All of Guptas friends were very supportive when they came out to them. So was Guptas older sister, who helped Gupta educate their parents about genderqueer people to avoid possible misunderstandings for whenever Gupta might choose to share their identity with the rest of their family. When they did, their parents accepted their child.

We were on vacation, I knew they would be more relaxed, Gupta laughed. I was saying how in queer spaces it was very common for people to say their pronouns and my mom said well, what pronouns do you say? I [said] yeah, Im genderqueer, and my mom was like, wow, shocker! She knew it was coming.

As a process of their coming out, Gupta began more openly expressing their queerness on social media. They started experimenting with their appearance, cutting their hair because having long hair no longer felt as though it was them. As of late, they have begun posting pictures of the way they changed thanks to the workouts they have taken on to make their body suit their mind better. But medically transitioning by going on testosterone, even though desired, feels like a risk too high to take right now. Guptas a musician and their voice might change in unpredictable ways if they were to start HRT.

So Im taking more time to think about it, what dosage I would need and finding the right doctor for my situation and stuff, Gupta said. I would look forward to being more muscular, my hips being less prominent wider face and neck! I would look forward to mostly just people looking at me and not automatically assuming Im a girl.

For each of these students, their path to becoming and presenting as themselves has been a complex one, and each of them finds themselves at a different place in their journeys.

Right now Gupta is getting ready to graduate, eagerly looking at their future and preparing new music for release. Their single Do You Ever will be available for streaming on May 15. August is currently living in New York as an openly trans person with their dog, Frank. They have fully recovered from their top surgery and model for We Speak Models. Elliott is continuing her journey with NYU as a graduate student, preparing to become an educator and feeling happy to have CHP insurance covering estrogen, which she started last spring as a part of her medical transitioning path.

Just like their transitions, the lives of August, Elliott and Gupta go on.

Correction, May 8:The last name of an individual profiled was removed upon request after publication. This article has been updated to reflect this and WSN regrets any errors.

Email Anna-Dmitry Muratova at [emailprotected] A version of this article appears in the Friday, May 8, 2020, print edition. Read more from Washington Square News While You Were Here 2020.

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Coming to University and Into Their Own - NYU Washington Square News


May 6

Why do women gain weight during menopause? – The Conversation AU

For most women, perimenopause the transition to menopause begins in their 40s. The entire menopause process typically lasts around four years and begins with the ovaries making less estrogen.

A woman is considered to be post-menopausal when she hasnt experienced a menstrual period for 12 months. This usually occurs between the ages of 46 to 52 years.

Read more: How to make work menopause-friendly: don't think of it as a problem to be managed

Symptoms of menopause can include irregular periods, hot flushes, fatigue, tender breasts, night sweats, vaginal dryness, difficulty sleeping, changes in mood and lower libido.

During menopause, hormonal changes can affect the way fat is distributed in the body, but ageing is more likely to be the cause of any weight gain associated with menopause.

Gaining weight isnt inevitable, though. Theres plenty you can do to combat weight gain as you age.

Certain areas such as your stomach are more prone to weight gain during menopause. This is because the change in hormones, which lead to a higher testosterone-to-estrogen ratio, alters where the body deposits fat. Fat comes off the hips and is deposited around the middle.

But the hormonal changes involved in menopause arent the reason you gain weight.

The weight gain that comes with menopause is a by-product of ageing.

As we age, our body stops working as efficiently as it did before. Muscle mass starts to decrease a process known as sarcopenia and fat begins to increase.

And because muscle mass is one of the determining factors of how fast your metabolism will run, when your muscle mass decreases, your body starts to burn fewer calories at rest. This might make it more challenging to maintain your weight.

Read more: Trick or treat? Alternative therapies for menopause

As we age, we tend to continue with our same food habits but dont increase our activity. In fact, aches and pains can make some people actively decrease theirs.

Not compensating for the ageing process and the change in body composition can lead to weight gain.

And this applies to men too they are just as likely to gain weight due to this process known as sarcopenia.

Due to a change in body fat distribution and increase in waist circumference, menopause can also increase your risk of other health conditions.

Read more: Hot flashes? Night sweats? Progesterone can help reduce symptoms of menopause

Following menopause, your ovaries make very little of the hormones estrogen and progesterone. Estrogen helps to keep your blood vessels dilated relaxed and open which helps keep your cholesterol levels down.

Without estrogen, or with lower quantities, your bad cholesterol (known as low-density lipoprotein or LDL-cholesterol) starts to build up in your arteries. This can increase your risk of heart disease and stroke.

Having less estrogen also results in a loss of bone mass, putting you at risk of the disease osteoporosis, which makes your bones more prone to fractures.

Weight gain associated with ageing is not inevitable. There are a number of things you can do to maintain your weight as you age.

1. Exercise

Incorporate regular daily exercise, with a mixture of intensities and variety of activities. Try to include body-strengthening exercises two days per week.

2. Weigh yourself but not too much

Weigh yourself once a week at the same time and day to monitor the trend over time. Any more than this will only create a fixation with weight. Day-to-day fluctuations in weight are to be expected.

3. Create positive habits

Create positive habits by replacing negative behaviours. For example, instead of mindlessly scrolling through social media of an evening or turning on the TV and comfort-eating, replace it with a positive behaviour, such as learning a new hobby, reading a book or going for a walk.

Read more: How to beat weight gain at menopause

4. Eat more slowly

Eat food away from technological distractions and slow down your food consumption.

Try using a teaspoon or chopsticks and chew your food thoroughly as slowing down your food consumption reduces the quantity consumed.

5. Switch off from technology:

Turn off technology after dusk to improve your sleep. Blue light emission from phones, tablets and other devices tell your brain its day, instead of night, which will keep you awake.

Lack of sleep (less than six hours per night) can compromise your decision-making abilities which might lead you to make unhealthy choices that contribute to weight gain.

6. Curb sugar cravings naturally

If youre craving sugar youre better off reaching for foods naturally high in sugar and fat first. Some great options are fruits, nuts, avocado and 100% nut butters. These foods release the same feel-good chemicals in the brain as processed and fast food and leave us feeling full.

Allow yourself your favourite treats, but keep them to once per week.

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Why do women gain weight during menopause? - The Conversation AU



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