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WESTERVILLE, Ohio --

For decades, Central Ohio has turned to NBC4 Chief Meteorologist Jym Ganahl for accurate weather forecasts delivered with Jyms bright smile, twinkling eyes and child-like giggle. He is trusted by generations of viewers who turn to him every evening, rain or shine.

Now Jym is tackling a health issue of his own, and volunteering to share this journey with viewers. Over the years, Jym has seen the pounds creep on, and the scale inch up, like many Americans. The extra weight complicates Jyms high blood pressure and knee problems. Jym had knee replacement surgery, and with weight loss hopes to avoid another.

But besides Jyms health, this proud military veteran is working to lose weight for a very special event, and to once again wear his Army uniform.

I always emcee the Veterans Day parade. Everyone is back in their Army uniforms, and every year I always say Im going to lose the weight to get in it, and Ive always failed, said Jym as he spoke with NBC4s Ellie Merritt at Bexa Body Fitness in Westerville.

This time, at 63 years old, Jym is aiming for success with a goal of losing 50 pounds by November for the Veterans Day parade.

My highest weight was 274...I felt embarrassed. I felt like a comedian trying to cover up, but I hated the way I looked, said Jym as he opened up about his weight and hopes to inspire others to get fit.

It just shows that even though you are on TV, you are still a real person. You have real life struggles. You still have those same normal things that everybody else goes through, said Rebecca Black, owner of Bexa Body Fitness who is helping Jym in his weight loss journey.

He's ready to get going, and we're excited to have him here. The first step is knowing you are ready and committing, and the second is getting your family on board. If your family is not on board to support you, find another support system or a friend to go with, said Black.

Charlie Jones is Jyms personal trainer who works out with him and guides him on his diet.

More here:
Jym Ganahl's Weight Loss Journey

QNA/Washington Scientists have developed a new drug which they claim can make you lose weight and keep it off for a longer period. Researchers from National Institute on Alcohol Abuse and Alcoholism in the US found that the new drug increases sensitivity to the hormone leptin, a natural appetite suppressant found in the body, the Science daily reported . The study was published in the journal Cell Metabolism. By sensitising the body to naturally occurring leptin, the new drug could not only promote weight loss, but also help maintain it, senior study author George Kunos from the institute said in a statement. This finding bodes well for the development of a new class of compounds for the treatment of obesity and its metabolic consequences, Kunos added. Although leptin is an appetite suppressant, leptin supplements alone have not been effective at reducing body weight in humans. Its thought that this is because of desensitisation to the hormone. Leptin is still there, but our bodies can no longer respond to it. While it is not entirely clear how this desensitisation occurs, cannabinoid receptors, which mediate the feelings of hunger produced by marijuana and naturally occurring cannabinoids in the body, are thought to be involved. So blocking these receptors, rather than providing excess leptin, could be more effective at long-term weight loss. In the new study, Kunos tested a new compound, JD5037, that targets cannabinoid receptor type 1 (CB1R) without penetrating the brain. JD5037 suppressed the appetite of obese mice, caused weight loss, and even improved metabolic health, in part by resensitising mice to the appetite-suppressing hormone leptin. Importantly, the mice did not show signs of anxiety or other behavioural side effects.

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New drug can make you lose weight: study

Saturday, July 28, 2012

LOOKING to lose a few pounds? Dying to get rid of that belly of yours? Thinking of spending a few hours at the local gym to trim that waistline?

Yeah. Good luck with that. You may lose weight for the short term, but that weight you lost will return and haunt you.

Win US$500. Join Sun.Star Cebu Yearbook Video Contest.

Sure you can drop a few pounds from proper diet and exercise, but you only lose weight because your fat is turning into muscle. It doesnt disappear; it just tenses up and goes to sleep.

People who lose weight through the traditional methods like working out, jogging, a low-carbohydrate diet and probably some yoga will be saddened to find out that the number of people who go from heavyweight to lightweight and stay there is so low that you can statistically round that off to zero. The number is still there, but its so miniscule that its depressing.

According to the fat activist blog Fat Fu, Weight Watchers works, for two out of a thousand. It also states that people who go from obese to normal weight and maintain it for more than a few years are so rare that nobody knows just how rare because no weight loss study has been large enough or rigorous enough to detect a significant number of them.

The thing about losing weight and staying thin is that, if you want those 20 or so pounds to be gone forever, you have to maintain your healthy lifestyle forever. Something easier said than done. That means eating the same healthy meals, doing the same exercise routines and basically staying fit until the day your body decides to give up.

An article published by CBS news about a study of a commercial weight loss program found it impressive that 50 percent of dieters in that particular program lost 5 percent of their weight and stayed there, which is like saying that its impressive that a person joined the program weighing 300lbs and is now at 285 and keeping it there.

The program restricted calories using a point system that made sure that the dieters lose a maximum of 2lbs a week. Points are spent through eating and earned through exercise. Five years later, most of the dieters had regained half of their original weight loss, which is sort of good since at least they didnt fa-whoom back into their 300lb old selves. Case in point: Mohammad Ali.

Read the original here:
Fat is forever

Scientists believe they may have found the right recipe for an obesity drug to help people lose weight and keep it off, without nasty side effects.

The drug, which is yet to be tested in humans, increases sensitivity to the body's appetite-suppressant hormone, leptin.

'By sensitising the body to naturally occurring leptin, the new drug could not only promote weight loss, but also help maintain it,' said study author George Kunos of the National Institute on Alcohol Abuse and Alcoholism in the US.

The drug works by reversing desensitisation to leptin, a process scientists think is caused by receptors that mediate hunger sparked by marijuana use and naturally occurring cannabinoids in the body.

Scientists have previously developed anti-obesity drugs to target cannabinoid receptor type 1 (CB1R), but one, rimonabant, was taken off the market in Europe because of serious side effects including anxiety, depression and suicidal thoughts.

Dr Kunos and his team minimised the side effects by developing a drug that targets CB1R without entering the brain.

Obese mice given the drug lost weight after their appetites were suppressed by increasing their sensitivity to leptin.

The mice did not express anxiety or adverse behavioural side effects.

'Obesity is a growing public health problem, and there is a strong need for new types of medications to treat obesity and its serious metabolic complications, including diabetes and fatty liver disease,' Dr Kunos said.

'This finding bodes well for the development of a new class of compounds for the treatment of obesity and its metabolic consequences.'

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Potential anti-obesity drug developed

Remember the experimental weight-loss drug rimonabant, touted as a potential "miracle pill" that could help obese smokers kick the habit, lose weight and keep it off for two years? Marketed in Europe as Acomplia, the drug made it well into the U.S. Food and Drug Administration's approval process before it was linked in 2008 to a doubling of depression risk in those taking it. The drug ended up withdrawn from the European market and pulled from FDA consideration, another failed medication on the ash heap of obesity treatments.

Or maybe not. A new study finds that a structural modification that prevents the active molecule from entering the brain might give a new lease on life to the the whole idea of promoting weight loss by manipulating the body's cannibinoid-receptor system.

In a study published in the journal Cell Metabolism, scientists gave obese rats a chemical variant of the drug that gave rimonabant its ability to bring about weight loss. The resulting agent, called JD5037, "robustly reduces food intake, body weight and adiposity" and was "devoid of behavioral effects," the researchers reported.

It did so by blocking the body's receptors for endocannibinoids -- messenger chemicals that play a role in metabolism and energy use as well as in mood, pain perception and satiety. While many of the body's cannibinoid receptors reside in the brain (hence their role in mood), some also operate in such organs as the liver and in fat -- which, in the obese, plays a powerful role in sending signals that say, in effect, "feed me."

But since scientists suspect that blocking cannabinoid receptors in the brain may wreak havoc on mood, the key here was to find a way to block cannabinoid receptors throughout the body but not in the brain's cortical regions. This is what they did, modifying a cannabinoid blocker called SLV319 so that it could not penetrate the blood-brain barrier.

Chubby rats put through a maze on the SLV319 became anxious and showed disrupted sleep patterns. But the rats given the structurally modified JD5037 suffered no such side effects, even as they lost weight. The study found that blocking cannabinoids in the body's "periphery" increased the body's sensitivity to the hormone leptin, which in turn increases the burning of fat for fuel and suppresses appetite.

In rats as well as people, obesity gradually drives down the body's sensitivity to leptin. Scientists believe this may be the mechanism that evolved to help us maintain or regain our stores of fat. That may work well for animals that must survive drought and starvation. But in modern times, when tasty calories aren't hard to come by for humans, it's what makes us hold onto or regain weight, even when we try to lose it through calorie restriction and exercise.

After seven to 28 days on JD5037, obese rats were not only slim, their circulating leptin levels were similar to those of lean, healthy mice, and their insulin resistance and fatty livers resolved.

By sensitizing the body to leptin of its own making, the authors wrote, the new chemical entity "may not only promote weight loss, but could help maintain it."

More here:
An abandoned weight-loss drug gets a makeover

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avanti.it

26 July 2012 Last updated at 03:56 ET

A retired civil servant has told of her shock at learning the weight she was struggling to lose was a football-sized tumour lodged in her stomach.

Val Best, 69, of Highwoods Square in Colchester, Essex, decided to get fitter after the death of her cab driver husband Roger in 2010.

Surgeons at Colchester hospital removed a tumour which weighed 7.5kg from the 69-year-old.

She said: "Now I'm absolutely fine, I'm fit and healthy, a new me."

The mother of four said her concerns grew because no amount of exercise seemed to shift the bulge over her abdomen.

"I was trying to lose weight after my husband died," said Mrs Best, who used to work in the job centre.

"I thought 'I'm getting older and I'm getting fat and I'd better lose weight or I'll get diabetes or something like that'.

"I wasn't succeeding and I was feeling like I was nine months' pregnant," she said. "But at 69 and a widow I thought I can't be nine months' pregnant. So I went to the doctor."

I did ask the surgeon whether he could do me a tummy-tuck at the same time but he said 'no'

Read more:
Weight loss woman's tumour shock

Vicki Bone, 20, says she is happy the way she is Admits she'd lose weight to help her fulfil dream of being a mother Boyfriend Jamie Beckwith accused of watching idly as Vicki eats herself to death - but says he's 'happy if she's happy'

By Deborah Arthurs

PUBLISHED: 06:35 EST, 25 July 2012 | UPDATED: 14:21 EST, 25 July 2012

They say that opposites attract - and rarely has that that truism been better illustrated than by the relationship of Vicki Bone and her partner Jamie Beckwith.

When it comes to appearances, the two couldn't be more different.

Vicki, 20, weighs 25st, while her childhood sweetheart Jamie weighs less than half that - weighing in at just 11st.

Now, the two, who have been together for five years, are keen to start a family.

Scroll down for video

Little and Large: Vicki Bone, who weighs twice as much as her boyfriend Jamie Beckwith, says she's happy the way she is - but will lose weight if it will help her to conceive

But not only could Vicki's weight be affecting her fertility - but she has been told by a doctor that if she doesn't lose weight, she will be dead by the time she is 40.

Excerpt from:
Obese 25st woman who weighs more than DOUBLE her 11st boyfriend is told lose weight - or you'll be dead by 40

By Karen Collins, MS, RD, CDN - Q: Ive heard too much time watching TV is linked with weight gain, but how much is too much? Q: Is giving up regular soda really enough to make me lose weight without going on a diet?

A: Going on a diet is not associated with long-term weight loss for most people, whereas working on a permanent change in one particular habit, such as reducing or eliminating sugary drinks, could be a great start for weight management. Controlled studies show that when people consume more calories from drinks, they dont compensate for those calories by eating less of other foods, and total calorie consumption tends to be higher. Changes in drink consumption alone can produce modest weight loss. In some cases, substituting water or diet (zero-calorie) beverages for sugar-sweetened soda is even enough to achieve the 5 percent weight loss linked with significant health improvement. About 25 percent of Americans consume more than 200 calories a day in sugar-sweetened drinks. If you are in this group, you are among those most likely to notice a weight change if you give up sugar-sweetened soda. Of course, this is assuming that you dont replace these drinks with juice or sugar-laden coffee or tea specialties or reward yourself for giving up soda by eating more cookies or other treats. Once your healthier drinking choices are an established habit, if you want to lose more weight, you can then look for other eating habits for which you can substitute lower calorie choices or smaller portions. On the other hand, if sugar-sweetened soda is something that you have only once a week or less, you can still focus on just one change in your eating habits to start losing weight, but youll see more results by changing something other than soft drinks.

Q: Ive heard too much time watching TV is linked with weight gain, but how much is too much?

Continued here:
HealthTalk: Weight Loss by Dieting; TV and Weight Gain

July 19, 2012 in Features, Health

Anthony L. Komaroff Universal Uclick

DEAR DOCTOR K: Im trying to lose weight. How can I figure out how many calories I should be eating everyday?

DEAR READER: Since your weight is influenced both by the number of calories you eat and by the number of calories you burn during your daily activities, lets assume that your daily activities wontchange.

To figure out how many calories you should consume each day to lose weight, you first need to know how many calories you need to maintain your current weight. The math issimple.

First, multiply your current weight by 15. This calculation tells you the number of calories per day you need to maintain your current weight (weight-maintenancecalories).

Lets say you weigh 155 pounds. If you multiply 155 by 15, you get 2,325, which is your weight-maintenance calorie total. To lose weight, youll need to reduce your daily calories belowthat.

To lose 1 to 2 pounds a week a rate that experts consider safe you should consume 500 to 1,000 fewer calories per day than your total weight-maintenance calories. That means you need to eat between 1,325 calories per day (2,325 less 1,000) to 1,825 calories per day (2,325 less500).

However, dont consume fewer than 1,200 calories per day if youre a woman or fewer than 1,500 calories per day if youre a man, except under the supervision of your doctor. Eating too few calories can endanger your health by depriving you of needednutrients.

Excerpt from:
Doctor K: Determine calorie total to drop weight - Thu, 19 Jul 2012 PST

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