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Feb 14

Trial Finds Semaglutide With Lifestyle Intervention Reduces Body Weight by Nearly 15% – Managed Markets Network

Obesity is a chronic disease that can lead to insulin resistance, hypertension, and dyslipidemia, and it is associated with type 2 diabetes (T2D), cardiovascular disease, and nonalcoholic fatty liver disease. Not only does it reduce life expectancy, but severe obesity has more recently been associated with increased risk of death from coronavirus disease 2019.

Lifestyle intervention, consisting of diet and exercise, remains the cornerstone of weight management, researchers wrote, but sustaining weight loss over the long term is challenging. Adjunctive pharmacotherapy is recommended for some patients in clinical guidelines, but uptake remains low due to modest efficacy, safety concerns, and cost. Currently, 5 medications are approved for use by the FDA for patients with overweight or obesity, and all require administration once, twice, or 3 times daily.

Semaglutide is approvedat doses up to 1 mg once weeklyfor the treatment of T2D in adults and to reduce risk of cardiovascular events in patients with T2D and comorbid cardiovascular disease.

Previous results from a phase 2 trial found that semaglutide induced weight loss in individuals with T2D and adults with obesity. According to authors, the treatments impact on weight loss stems from a reduction in energy intake owing to decreased appetite, which is thought to result from direct and indirect effects on the brain.

To determine if the treatment, injected subcutaneously, is safe and effective in individuals with overweight or obesity, with or without weight-related complications and absent of T2D, researchers conducted a randomized, double-blind, placebo-controlled trial.

The global phase 3 Semaglutide Treatment Effect in People with Obesity (STEP) 1 program took place at 129 sites in 16 countries throughout Asia, Europe, North America, and South America. It was funded by Novo Nordisk, which produces semaglutide. All participants were 18 years or older, self-reported 1 or more unsuccessful dietary effort to lose weight, and had a body mass index (BMI) of 30 or greater, or a BMI of 27 or greater with 1 or more weight-related condition. Any participant with diabetes or previous surgical obesity treatment was excluded from the trial.

Patients were randomized 2:1 to receive 2.4 mg of semaglutide once a week for 68 weeks or a matching placebo, in addition to lifestyle intervention. Participants initially received a 0.25 mg dose once weekly. After 4 weeks, doses increased every 4 weeks to reach 2.4 mg weekly by week 16, while lower maintenance doses were permitted if participants reported unacceptable adverse effects with the 2.4-mg dose.

Lifestyle intervention included counseling sessions every 4 weeks to help participants adhere to a reduced-calorie diet and increase physical activity (150 minutes per week was encouraged). Daily diet and activity were recorded in a diary, via a smartphone application, or using other tools.

A total of 1961 participants were assigned to receive semaglutide (n = 1306) or placebo (n = 655) between June and November 2018, while 94.3% completed the trial, 91.2% had a body weight assessment at week 68, and 81.1% adhered to treatment. Throughout the study window, rescue interventions were received by 7 participants in the semaglutide group (2 had bariatric surgery and 5 received other antiobesity medication) and by 13 in the placebo group (3 had bariatric surgery and 10 received other antiobesity medication).

The majority of participants were White (75.1%) women (74.1%) with a mean age of 46 years and a mean body weight of 105.3 kg. At baseline, mean BMI was 37.9, mean waist circumference was 114.7 cm, and 43.7% of participants had prediabetes. Three-fourths of participants also had at least 1 coexisting condition (hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease).

Analyses revealed:

Those who received semaglutide also exhibited greater reductions in waist circumference, BMI, and systolic and diastolic blood pressure compared with placebo, and had improved levels of glycated hemoglobin, fasting plasma glucose, C-reactive protein, and fasting lipid levels after 68 weeks. These participants reported greater increases in physical functioning from baseline compared with placebo.

Gastrointestinal disorders, including nausea, diarrhea, vomiting and constipation, were the most frequently reported events and occurred in 74.2% of those who took semaglutide compared with 47.9% of the placebo group. Approximately 10% of those who took semaglutide reported serious adverse events, compared with 6.4% in the placebo group, with the difference due primarily to a difference between the groups in the incidence of serious gastrointestinal disorders and hepatobiliary disorders, researchers wrote. In the semaglutide group, 2.6% of participants reported gallbladder-related disorders compared with 1.2% of the placebo group, and those who took semaglutide reported higher rates of cholelithiasis.

Weight reductions achieved with semaglutide were substantially greater at 14.9% compared with weight loss from baseline achieved using approved antiobesity medications, which ranges from 4% to 10.9%, researchers noted.

Previous research has found that 3 mg of daily liraglutide (the only GLP-1 receptor agonist approved for weight management) resulted in a 4.5% reduction in mean placebo-corrected weight after 56 weeks, compared with 12.4% seen with semaglutide after 68 weeks. However, authors cautioned that the 2 studies differed in participant population, limiting between-study comparisons.

It is important to note that oral semaglutide has been associated with pancreatitis and, in rodents, with thyroid C-cell tumors, which include medullary thyroid carcinoma, the authors of an accompanying editorial2 pointed out.

The majority female, White study population marks a significant limitation to the trial in that results may not be generalizable to the wider American public. Researchers also noted the relatively short duration of the trial and the potential that participants may represent a subgroup with greater commitment to weight-loss efforts than the general population, presenting further limitations.

In the United States, the prevalence of adult obesity increased from 30.5% in 1999-2000 to 42.4% in 2017-2018, while the presence of severe obesity jumped from 4.7% to 9.2%, according to the CDC. Obesity affects 1 in 5 American children and adolescents and the risk of developing T2D is4 times greaterfor obese children compared with those at normal weight.

Although several treatments including lifestyle modification, metabolic surgeries, and pharmacotherapies are being developed to combat this trend, research indicates that in less than 10 years, over half of the countrys population will be obese. Should these numbers continue to increase, estimated projected obesity-related medical costs could rise by $48 to $66 billion a year in the United States.

Moving forward, head-to-head trials comparing oral GLP-1 agonists with sodium glucose co-transporter (SGLT)-2 antagonists or other weight-loss medications will be necessary, authors wrote in the editorial. Given the effectiveness of bariatric surgery in regard to both weight loss and glucose tolerance, studies comparing these two distinct forms of therapy (surgery and pharmacologic therapy) will be required, they concluded.


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Trial Finds Semaglutide With Lifestyle Intervention Reduces Body Weight by Nearly 15% - Managed Markets Network

Feb 14

When and how to use protein to optimize your fitness goals, lose weight, and gain muscle – Insider

Protein, the macronutient that helps build muscle and repair tissues, is often touted as the backbone of a healthy diet or exercise routine.

But advice about how much and when to eat your protein is often confusing and contradictory. You come across warnings about getting too much, too little, or using it at the wrong time.

Getting the right amount of protein for your fitness goals doesn't have to be hard, according to Nancy Clark, a sports dietitian with a private practice in the Boston area.

"People make eating so complex, it's supposed to be simple," Clark told Insider as she shared her five key pieces of protein advice.

Balancing protein through the day, eating it with other key nutrients, and picking the right sources, she said, can help your optimize your fitness success whether your goal is weight loss or muscle gain.

The biggest misconception about protein is that you need huge amounts to build muscle, according to Clark. That's not the case. A moderate amount of protein is ideal for most people trying to either gain muscle or lose fat, she said.

That means about half to three-quarters of a gram of protein per pound of body for most active people, Clark said.

You'll want slightly more than this up to a gram per pound if you're new to exercise, to help repair broken-down muscle. A bit more protein can also help with weight loss goals, since dietary protein can help preserve muscle mass as you're losing fat.

You may also need more if you're vegan, Clark said, as many plant-based proteins are incomplete, lacking certain amino acids, so you'll want to eat a variety of protein sources.

It is possible to eat too much protein, if you're getting more than 30% of your daily calories from protein. But that's not likely to be an issue for most people, and causes only minor side effects unless you have a pre-existing kidney or liver problem.

Heaping protein into your diet won't supercharge your progress, however, and could backfire.

"Extra protein in your diet doesn't convert into extra muscle. You can eat as much protein as you want, and if you're not doing resistance training, you won't build muscle," Clark said.

And protein contains calories just like carbs and fat, so too much of it can cause you to gain body fat, which is important to keep in mind if you're trying to lose weight or build muscle.

Another common mistake for both weight loss and muscle gain is excessively cutting carbohydrates. Contrary to what some diet plans like keto suggest, carbohydrates like grains, fruits, and vegetables are an important source of energy and great for muscle recovery. It's best to include them alongside protein to optimize a lean physique, Clark said.

"I hate the word 'carb,' it's very tainted," she said. "Carbohydrates digest into glucose which feeds your brain and fuels your muscles."

Carbohydrates are even more important for athletes, who should get about three times as much carbohydrate as protein in their diet, according to Clark.

"If you're a sports-active person, it behooves you to have that be the foundation of your meal," she said.

Despite what legions of shake-chugging gym rats will tell you, it's not necessary to consume a lot of protein immediately after a workout.

It's true that if you're an elite, competitive athlete, post-exercise refueling can give you an edge, Clark said, particularly if you have multiple, intense workouts in a single day.

More casual athletes, though, can get adequate protein throughout the day."For most ordinary mortals, they need not worry too much about it.The sooner you refuel, the faster the recovery process starts, but it can happen within 24 hours," Clark said.

When you do eat protein, the benefits for refueling and tissue repair typically last about four hours, she said. That means it's best for most people to space out their protein intake throughout the day.

That's why diet strategies like intermittent fasting can put you at risk of losing muscle and stymieing your progress, Clark said.

For a more successful workout, she recommends consuming about 200-300 calories a mix of carbs and protein soon before a workout.

Refueling doesn't have to involve an expensive shake or supplement, either (although they can help you get enough protein). A simple peanut butter and jelly sandwich is an easy after-exercise snack that's portable and has a good balance of nutrients, according to Clark.

"[Protein supplements] are pre-wrapped, convenient, easily available, but they aren't magic.Real food always works better. Your muscles don't need just protein, they need a whole complex matrix of nutrients," Clark said.

It's best to focus on building balanced meals and snacks; aim for making about a third of your plate healthy protein, a third veggies or produce, and the remainder healthy carbs, she recommends.

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When and how to use protein to optimize your fitness goals, lose weight, and gain muscle - Insider

Feb 14

Weight Loss: Choose Traditional Breakfast Over Cereals When Trying To Shed Kilos – NDTV

Weight loss: A healthy breakfast can support your weight loss process

You might have come across several tips that can help in weight loss. From weight loss-friendly drinks to magic concoctions, multiple ingredients have gained popularity. For effective weight loss, you need to burn more calories than you consume with a healthy diet and lifestyle. Similarly, making a few changes can help you reach your goal effectively. Factors like your sleep schedule, right breakfast choices, levels of physical activity, how you eat meals, time spent in eating and the timings of the meal also play a role. If you are also trying to lose weight, here are some effective weight loss tips you need to follow.

Celeb nutritionist Munmun Ganeriwal took to social media and shared some weight loss tips as part of her Instagram series QuickFivewithMG. Here are some do's and don't for weight loss she mentioned-

Many choose readymade cereal for breakfast due to lack of time. Unlike fresh homemade breakfast, convenient-ready-to-eat meals are often loaded with preservatives and artificial flavouring agents that are harmful to health. These are also often loaded with added sugar that can affect your weight loss process. Instead stick to traditional breakfast options like poha, upma, idli etc.

Weight loss: Prepare fresh breakfast at home for better nutritionPhoto Credit: iStock

The nutritionist explains, "Tea and coffee contain caffeine that triggers the release of cortisol (stress hormone) and puts the body in a stress mode. When you wake up, your body needs time to get back to functioning in full capacity. In such a situation, it is better to eat real food instead of something that can further stress it out."

If you love drinking teas, try herbal teas within 30 minutes of waking up. You can also choose shakes, smoothies or protein shakes for breakfast. Avoid drinking packed juices.

Also read:Weight Loss: Dietician Reveals 3 Truths That Will Help You In The Long Run

It is often advised to exercise for at least 30 minutes a day. "Current research findings of ACSM (American College of Sports Medicine) indicate that moving more during the day, in addition to getting 150 mins/week of exercise is necessary to reduce one's risk of diseases and to lose weight," Ganeriwal mentions in her post. Not moving enough also puts you at a high risk of weight gain and several health conditions.

You can start your day with exercising. Also, take small breaks and move around for 2-3 minutes. Stretching can also help you keep back, shoulder and neck pain at bay.

Also read:Here Are The Reasons Why You Should Eat White Rice Guilt-Free

Weight loss tips: Exercise regularly to burn more caloriesPhoto Credit: iStock

When you are paying attention to your meal while eating, it will give you the satiety signals at the right time and you will know exactly when to stop eating. People are usually busy using mobile phone while eating and end up consuming more calories than required.

Also read:Weight Loss: Is Eating Roti Better Than Eating Rice For Losing Weight?

When you are exposed to light-emitting gadgets, your body goes becomes alert and delays sleep. Using gadgets before bed can make you take longer to fall asleep. Lack of sleep also makes you consume more calories and increase stress. You will also wake up tired with low energy levels.

Follow these effective tips and hope you reach your weight loss goals soon!

(Munmun Ganeriwal is a Nutritionist, Fitness Expert and Yoga Teacher at Mumbai)

Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.

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Weight Loss: Choose Traditional Breakfast Over Cereals When Trying To Shed Kilos - NDTV

Feb 14

Your thyroid and your weight loss – The Durango Herald

If you are worried about your thyroid, think it may be causing you to gain weight or have noticed your thyroid numbers changing as you lose weight, read on.

In addition to weight gain and stalled weight loss, low thyroid hormone levels, known as hypothyroidism, can cause you to suffer from feelings of cold, constipation, brain fog (memory or concentration issues), fatigue and lack of motivation among other things. You may also notice excessive sleep, feelings of or actual clinical depression, hair loss, mood swings or dry skin.

Thyroid dysfunction is estimated to affect up to 15% of the population at some point in their lifetime. Women are up to eight times more likely to be affected than men, and the numbers go up as you age. While that is a lot of people, some estimate that more than half of those with thyroid dysfunction do not know they have it. Incredibly, thyroxine, the most frequently used medication to treat hypothyroidism, is already one of the most frequently prescribed medications in the country.

So, why so much thyroid dysfunction? Is the thyroid the true culprit for our obesity epidemic? Or is it the victim?

The thyroid gland is in the lower front end of the neck and produces thyroid hormones. These hormones are responsible for communicating with nearly every cell of your body, and they regulate the speed of all the biologic machinery that makes you function. Unfortunately, with a plague of chronic stress, nutritionally depleted food sources, contaminated water and frequently toxic environments, our thyroid may not be functioning how we would like it to.

While there are many hormones that play a role in the production of or suppression of thyroid function, the hormones directly involved include thyroid secreting hormone, T4 and T3. The later two can also be measured as free T4, free T3 and reverse T3. TSH is the hormone that stimulates secretion of thyroid hormone and is the most frequently tested hormone when assessing thyroid health. The problem is that this hormone doesnt show the whole picture.

TSH levels can remain within range despite significant thyroid dysfunction and sometimes look off despite normal function, particularly when recovering from obesity.

When assessing thyroid health or looking for an autoimmune cause of dysfunction, the measurable thyroid hormones and antibodies should all be ordered. Even if the correct tests are run, only a partial picture, of the thyroid state of being can be revealed. There are myriad additional labs that could be ordered to help complete the picture including sex hormones and nutrition labs, but even with all this information some aspects of thyroid function are not fully known, and the interaction with food and energy consumption is one of them. To understand each individual situation, the symptoms, labs and history must be considered.

So what happens when you lose weight, and does weight loss cause hypothyroidism? You can be fairly certain that your hormone levels will drop with weight loss. This is often normal and can be completely explained by the higher hormone levels associated with obesity beginning to normalize with successfully achieving optimal body alignment. Reduction in hormone levels could merely represent your body coming back to homeostasis. However, some weight loss can result in worsening thyroid function to varying degrees. According to Dr. Doug Lucas, PHD Weight Loss chief science officer, two factors worth considering are: 1) the extent of calorie restriction and 2) the type of dietary fat consumed. These two items appear to play the largest roles in determining the deleterious effects of weight loss on your thyroid. Choosing the right approach can separate weight loss and maintenance successes from failure.

Severe calorie restriction and the consumption of highly processed polyunsaturated fats (e.g., vegetable oils) can negatively affect the thyroid. Research shows that carbohydrate restriction alone, and especially when done with healthy dietary fat consumption, will have much less effect on T3 levels and function. If you experience reduced T3 levels, but are following this dietary approach with a well-formulated meal plan, it is likely the result of normalization of your hormones as weight is let go and optimal body alignment is achieved. Lower levels could also be evidence of a more efficient system and less demand for thyroid function. As a bonus, human studies about longevity demonstrate an association of a longer life with lower levels of T3. Reduced T3 without symptoms is likely a sign of a well-functioning system that has reached optimal alignment and efficiency.

If youre looking to support your thyroid while dropping weight or maintaining weight loss, here are some tips:

Dont simply restrict calories and exercises more to lose weight. How you drop weight is key to maintaining a healthy thyroid.According to Doug Lucas, optimizing your sleep, stress and toxic exposures has significant impact on thyroid health as well.Avoid foods known as goitrogens. These are toxic for your thyroid. These include gluten, grains, dairy, nightshades (eggplant, peppers, tomatoes, white potatoes), sugar, caffeine, alcohol and for those with possible or confirmed autoimmune cause of thyroid dysfunction, eggs. Cruciferous vegetables can and should be consumed if possible, but if you are worried about your thyroid consider cooking or fermenting these nutrition-packed plant foods. If you choose to consume dairy, try goat products or A2 cow products. There is a tremendous amount of noise and misinformation about the thyroid. An accurate diagnosis and good understanding of what is happening can help you feel empowered and confident. Remember that thyroid hormone levels are not as important as how you feel. If you are concerned, start with the basics: sleep, stress and nutrition. If you have symptoms, consider working with your health care team to determine if treatment is right for you. If youre in the process of dropping weight or are following a lower carbohydrate lifestyle, fluctuations may well be temporary and a new set point may be established while your body adjusts to its new optimal you.

Ashley Lucas has a doctorate in sports nutrition and chronic disease. She is also a registered dietitian nutritionist. She is the founder and owner of PHD Weight Loss and Nutrition, offering weight management and wellness services in the Four Corners. She can be reached at 764-4133. She is married to Dr. Doug Lucas, who is an orthopedic surgeon and precision medicine physician.

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Your thyroid and your weight loss - The Durango Herald

Feb 14

Is the vegan diet better than the Mediterranean diet to lose weight? – Market Research Telecast

Provided by BekiaIs the vegan diet better than the Mediterranean diet to lose weight?

Studies show this and a vegan diet it is much more effective when it comes to losing weight than the Mediterranean diet. Such a vegan diet must be low in fat so that the person can lose a few extra pounds. This is not to say that the vegan diet is much healthier than the famous Mediterranean diet.

If you want to lose some weight and shed a few extra kilos, a specific vegan diet and with the right foods can help you. The key to this is to avoid vegan foods that are healthy but high in fat, such as olive oil, nuts or avocado.

For a vegan diet to help a person lose weight, a series of guidelines must be followed:

The Mediterranean diet is highly recommended for health but it does not help you lose those extra pounds. Foods like dairy, meat, or oily fish They are good for the body, but their high amount of fat does not help a person lose weight.

There are many studies that indicate that in the medium and long term, you lose weight with a proper vegan diet. If a good diet is followed, the person can lose about 5 or 6 kilos in 4 months. Apart from this, the vegan diet is perfect when it comes to reducing blood cholesterol levels and keeping blood pressure at bay.

There are several reasons why weight is lost when following a vegan diet. The main cause is due to low calorie intake, something that is essential when it comes to shedding those extra pounds. It must be remembered that fats are quite caloric, so when reducing them, significant weight loss is normal.

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Is the vegan diet better than the Mediterranean diet to lose weight? - Market Research Telecast

Feb 14

The egg diet for weight loss: Know more about the benefits, risks and sustainability of the low-calorie diet – Times Now

The egg diet for weight loss: Know more about the benefits, risks and sustainability of the low-calorie diet  |  Photo Credit: iStock Images

New Delhi: Weight loss requires you to follow a disciplined, and healthy diet to help your body shed the extra kilos it does not need. Given obesity or being overweight is linked with so many health disorders such as high risk of type 2 diabetes, cancer, and even COVID-19, it is imperative to make efforts to reach and maintain a healthy Body Mass Index which is the weight to height ratio.

However, as people have adopted to healthier lifestyles and measures to lose weight, a new industry of weight loss products, diets, and tips has come up. While some of these are healthy, others are subjective, and some are outrightly bizarre, unsustainable, and unhealthy fad diets. A diet that has recently become very popular for weight loss is the Egg Diet. Let us find out which of the above categories does the Egg diet fall into.

The egg diet is a low carb, low calorie but high-protein diet. According to SimrunChopra, Deep Health Coach and Founder, Nourish with Sim, The egg diet promises abnormally fast weight loss benefits. It claims to avoid losing muscle mass. This is just another fad diet.

The egg diet plan does not seem to be a sustainable weight loss plan. Accoridng to Ms Chopra, The whole plan is unsustainable. Imagine eating only eggs or loads of eggs with little or no variation in your diet, for the rest of your life. Dont forget all the down-sides of eating too many eggs. Flatulence, fatigue and a bad mood are likely to accompany such a diet if sustained for too long.

There is no doubt that if you can sustain the plan, you are likely to lose weight because the diet will help you create a calorie deficit. However, you may not be able to maintain the lost weight, only coming back to square one, very soon. While you will lose weight, your body will most likely rebound in very little time, post completion of the diet. I have come across various variants of the egg diet. Egg-only fasts, sometimes adding a fruit or vegetable or even cheese, Ms Chopra added.

While a diet that comprises only of eggs may not be the ideal way for weight loss, one cannot deny that eggs are a super-food, and very helpful in weight loss if consumed correctly. Ms Simrun also agrees and says, Having said all of the above, it is true that the egg is a super-food. Not only that, they are affordable and very versatile, being used in any number of ways. However, focusing on just one food item is never a good idea. I believe these kinds of mono-diets do more damage than good.

While eggs are a super source of healthy fats, have around 6 grams of protein, contains Vitamin A, B12 and D, is a source of choline (for the brain), selenium and riboflavin and has more than its fair share of antioxidants, you cannot live on eggs alone. Your body is a complex structure that has a variety of needs. Needs that can only be met with the proper consumption of nutritious foods.

So, while the egg is a very healthy food, the egg diet is not a healthy, balanced diet. Diets that are so restrictive, this low-calorie and focused on one food only are never successful over the long term. Another aspect to consider when looking at the egg diet is the inherent dietary cholesterol in an egg. Each egg is estimated to have 184 mg of cholesterol. Eggs have also been flagged for its saturated fat content. While these factors do not make it something to be avoided, it is best to consume eggs in moderation, especially if you have pre-existing medical conditions.

It is recommended that you never consider diets that are restrictive. This makes the plan an inefficient and unsustainable one. Always choose a diet plan that includes and encourages consumption of healthy foods like lean proteins, eggs, fruits and vegetables and high fibre foods like whole grains and beans. Because eggs have absolutely zero fibre, this will cause problems like constipation. All of the above, when eaten in moderation, as per a sustainable diet plan will give you all the vitamins, minerals and antioxidants needed by the body to function properly.

Disclaimer: Tips and suggestions mentioned in the article are for general information purpose only and should not be construed as professional medical advice. Always consult your doctor or a dietician before starting any fitness programme or making any changes to your diet.

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The egg diet for weight loss: Know more about the benefits, risks and sustainability of the low-calorie diet - Times Now

Feb 5

Are you struggling with a stress belly? 6 things you can do to get rid of abdominal fat, boost weight loss – Times Now

Are you struggling with a stress belly? 6 things you can do to get rid of abdominal fat, boost weight loss  |  Photo Credit: iStock Images

New Delhi: Everyone experiences stress from time to time. But prolonged stress can cause a range of physical and mental health problems. It can also lead to unwanted weight gain, especially around the middle. Research has shown that stress can cause excess abdominal fat in otherwise lean women. Also known as stress belly, which is a way to describe how stress and stress hormones affect your belly, abdominal fat is linked with serious health issues, including a greater risk of heart disease, type 2 diabetes and breathing problems. The good news is, theres a lot you can do to get rid of stress belly or boost your weight loss.

Basically, stress belly is not a medical diagnosis, its a way of describing how stress and stress hormones can affect your weight, especially your belly. For instance, higher levels of cortisol - the primary stress hormone - have been associated with abdominal obesity. This crucial hormone produced in the adrenal gland also helps with blood sugar control, metabolism and many other functions in the body. Cortisol, along with other hormones like adrenaline, is a part of the bodys fight or flight response that occurs when faced with a crisis. During a stressful event, cortisol levels rise to give you a surge of energy to help you deal with the event. And once the stress is addressed, everything returns to normal.

However, prolonged and constant feeling of stress can affect your health in many ways, including raised blood pressure, increased blood sugar levels and elevated stress cortisol levels. Raised cortisol levels triggered by chronic stress have been associated with weight gain and abdominal obesity.

For instance, a study published in the journal Psychosomatic Medicine reported that individuals with higher levels of cortisol in their bodies tended to have larger waist measurements and a higher body mass index (BMI) compared to those with lower levels. Similarly, a 2018 review study found that higher long-term cortisol levels are strongly linked to having abdominal obesity.

However, it may be noted that not all people with obesity have high cortisol levels, since genetics may play a role in glucocorticoid sensitivity.

Various factors, including age and genetics, influence where your body stores fat. But there are many things you can do to lose belly fat and maintain weight loss. Here are a few tips that you can follow:

The bottom line is, whether or not you have a stress belly, a sensible lifestyle will help prevent disease and promote a healthier, fitter life.

Disclaimer: Tips and suggestions mentioned in the article are for general information purpose only and should not be construed as professional medical advice. Always consult your doctor or a dietician before starting any fitness programme or making any changes to your diet.

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Are you struggling with a stress belly? 6 things you can do to get rid of abdominal fat, boost weight loss - Times Now

Feb 4

Rebel Wilson weight loss how did the actress lose weight? – The Sun

REBEL Wilson shocked fans this week when she posed for an Instagram shot for her 9.5 million followers.

The Pitch Perfect star looked unrecognisable having embarked on a new health and fitness journey.



The 40-year-old captioned the photo: "Lots on my mind...aghhhhhh...#single-girl-heading-to-Super-Bowl!", confirming her split from billionaire boyfriend Jacob Busch.

But how did Rebel lose more that 60 pounds after declaring 2020 as a "year of health"?

At the time, she wrote on Instagram: Okay so for me 2020 is going to be called The Year of Health.'

So I put on the athleisure and went out for a walk, deliberately hydrating on the couch right now and trying to avoid the sugar and junk food, which is going to be hard after the holidays Ive just had but Im going to do it! Whos with me in making some positive changes this year?

She revealedher target weightof 165 pounds (11.7 stone) to her fans.

Even if you have to crawl towards your goals, keep going x it will be worth it, shecaptioned a photo of herselfin a tracksuit and bra.

Try and give a little bit of effort each dayI know some days are frustrating as hell, you feel like giving up, you get annoyed at the lack of progressbut good things are coming your way," she encouraged.

Rebel previously said that she had embraced the Mayr Method as well as working out with her trainer.

She reached her goal weight in November last year.

The diet is based on the book by Dr Harald Stossier and Helena Frith Powell.

The plan focuses on your gut and how the foods you eat ultimately affect your digestive system.

Most people will just buy the book but for those with a little more cash, they will visit a Mayr centre in Austria or London.


Rebel previously posted about the centre in Austria.

Here you will spend a week having your diet and routine scrutinised by experts who will help you with your snacking and reducing gluten and dairy intake - this will cost around 1,600 for the week.

The diet is not calorie controlled but you will be taught how to chew your food and will be encouraged to eat slowly.

People following the plan will have their biggest meal at breakfast and their smallest meal at dinner time.

Its website states: "VIVAMAYR combines modern complementary medicine with traditional diagnostics and therapies according to F.X. Mayr.

"Once we have treated your condition, proper nutrition combined with exercise and improved mental awareness become the building blocks of your new life.

"Modern Mayr Medicine is based on the four principles of Rest, Cleanse, Train and Substitute with the goal of integrating and practicing each principle individually for a period of time."

Aside from diet and wellness, Rebel has also been working out with personal trainer Jono Castano.

She regularly posts videos on her Instagram stories and part of her workouts include strength building such as flipping tyres.

As well as strength exercises she also makes sure to include cardio and incorporates sprint and high intensity interval training.

She also posts about going for hikes and long walks outside.


While it's important to include all of the major food groups in your diet, Rebel recently told People magazine that she had cut down on the amount of carbs and had upped her protein intake.

She said: "Before I was probably eating 3,000 calories most days, and because they were normally carbs, I would still be hungry.

So, I've really changed to eating a high-protein diet, which is challenging because I didn't used to eat a lot of meat. I eat fish, salmon, and chicken breast.

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While Rebel has overhauled her image, she also said that she won't restrict herself and added that "nothing is forbidden".

She said she will still have take-out but that she might just eat half or have a smaller portion than she previously would have.

Rebel has also previously talked about emotional eating and said that food was something she used to cope with becoming internationally famous.

She added: "There is a lot of stress that comes with it, and I guess my way of dealing with it was just eating donuts."

Excerpt from:
Rebel Wilson weight loss how did the actress lose weight? - The Sun

Feb 4

Rebel Wilson Says People Treat Her Differently Following Her 60-Pound Weight Loss –

After losing more than 60 pounds in 2020, Rebel Wilson reflected on her Year of Health on The Morning Crew with Hughesy, Ed and Erin. The 40-year-old actress opened up about sharing her weight loss journey publicly on Instagram, and the reactions shes received after reaching her health goals.

I liked to think I looked good at all sizes, Wilson said. And Ive always been quite confident, so its not like I wasnt confident and now Im super confident.

One thing that did change? Whats been interesting is how people treat you. Sometimes being bigger, people didnt necessarily look twice at you, she said. Now that Im in good shape, people offer to carry my groceries to the car and hold doors open for [me].

This led her to wonder whether people of smaller sizes have these interactions without even realizing it. That, to me, has been really interesting, she said.

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Wilson has also been surprised by the amount of attention shes received on social media. I find it interesting that people pay so much attention to a weight loss transformation when theres so much going on in the world, she admitted.

Throughout 2020, Wilson documented her weight loss journey on Instagram, revealing all of the big and small changes she made to her diet, fitness, and self-care routine to reach her goals. This included hitting the gym most days of the week, lots of walking, and reaching for more nutritious foods (with a few treats sprinkled in).

The actress previously shared that she struggled with emotional eating, and in an IGTV from December, she explained that its still something she has to pay attention to if shes feeling particularly stressed or anxious. Its not something thats just going to disappear, its just something I have to manage now moving forward, she said.

Despite her weight loss, Wilsons not focused on the number on the scale. Instead, she tunes into how shes feeling. I would say to everyone out there dont be obsessed about how much you actually weigh, she told People. Its more about all the healthy practices, and then the changes to your whole lifestyle.

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Rebel Wilson Says People Treat Her Differently Following Her 60-Pound Weight Loss -

Feb 4

Using nutrition to lose weight Film Daily – Film Daily

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Using nutrition to lose weight Film Daily - Film Daily

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