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Public release date: 23-Jun-2012 [ | E-mail | Share ]

Contact: Aaron Lohr alohr@endo-society.org 240-482-1380 The Endocrine Society

Obese older adults can reduce their chance of developing the metabolic syndrome by losing weight through dieting alone, but adding exercise to a weight loss program has even more benefit, a new study finds. The results, to be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston, show that a combination of diet-induced weight loss and frequent exercise almost doubled the improvement in insulin sensitivity compared with dieting alone.

The metabolic syndrome is a cluster of metabolic problems that raise the risk of Type 2 diabetes and heart disease: abdominal obesity as shown by a large waist circumference, disturbed lipids (low HDL or "good" cholesterol and high triglycerides), high blood pressure and high blood glucose (blood sugar). Although it is known that weight loss can reduce these risk factors, the most appropriate lifestyle treatment for obesity in older adults has been controversial, said the presenting author, Matthew Bouchonville, MD.

"It was not clear from prior studies in obese elderly adults whether the beneficial effects of diet and exercise are distinct from each other or have additive effects," said Bouchonville, an assistant professor at the University of Mexico Health Sciences Center and the New Mexico Veterans Affairs (VA) Health Care System in Albuquerque.

The researchers investigated the independent and combined effects of diet-induced weight loss and regular exercise in a one-year randomized controlled clinical trial, funded by the National Institute on Aging. They randomly assigned 107 obese adults ages 65 and older to one of four groups: weight management using a calorie-restricted diet, exercise (three times a week for 90 minutes each) without dieting, combined dieting with exercise, and controls (no diet or exercise).

The primary outcome analyzed was the degree of change in the insulin sensitivity index. Insulin sensitivity is the body's ability to successfully clear glucose from the bloodstream and is often impaired in obese people. This index was measured from the oral glucose tolerance test, a blood test for diabetes after the patient drinks a sugary drink.

Other measures obtained included those for the components of the metabolic syndrome as well as C-reactive protein, a measure of inflammation. Research has linked chronic inflammation to diabetes and heart disease.

Ninety-three participants completed the study. In the intention-to-treat analysis of all 107 subjects, the insulin sensitivity index did not improve in the exercise-alone group or the controls. This index did improve on average by 40 percent in the diet group and by 70 percent in the combined diet-exercise group after controlling for relevant covariates, Bouchonville reported.

"This suggests a distinct complementary effect of exercise on diet-induced weight loss," he said.

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Exercise with diet improves insulin sensitivity much more than diet alone

Diet high in fat and calories can hasten the development of pancreatic cancer in humans.

Our results showed that in mice, a diet high in fat and calories led to obesity and metabolic disturbances such as insulin resistance that are seen in obese humans. It also greatly enhanced pancreatic inflammation and pancreatic cancer development, said Guido Eibl, M.D., an associate professor in the department of surgery at the David Geffen School of Medicine at the University of California, Los Angeles and a researcher at UCLAs Jonsson Comprehensive Cancer Center.

Human epidemiological studies have linked high fat intake and obesity to an increased risk of pancreatic cancer, but the mechanism driving this association has not been understood.

To understand the link, Eibl and his colleagues first tested the hypothesis that diet is linked to cancer. They fed a corn oil-based diet that had a high content of fat and calories to mice with a genetic mutation that caused them to develop pancreatic precancer. The same gene, KRAS, is mutated in the majority of human pancreatic cancers.

The results showed that 90 percent of the mice fed the special diet became obese, and all of these mice developed insulin resistance and inflammation in the pancreas. Both of these conditions can stimulate the growth of precancerous cells and cancer. These mice also developed significantly more advanced precancerous lesions than did mice fed a normal diet.

This suggests that the high-fat, high-calorie diet accelerated pancreatic cancer development, said Eibl. A KRAS mutation in the pancreas might not be sufficient to cause an individual to develop pancreatic cancer. It likely needs something in addition a secondary hit. Our study showed that a high-fat, high-calorie diet could provide an environmental secondary hit and trigger cancer development.

The researchers are now defining the role that inflammation produced by obesity plays in development of the cancer, and if agents such as antidiabetic drugs or fish oil can halt this disease process.

Continue reading here:
High-fat, High-calorie Diet Speeds Pancreatic Cancer Development

Of course, you need a healthy balance of both the right diet and adequate exercise to drop the pounds. But does one outweigh the other? Find out.

This has been an ongoing controversy for many years. For optimal fat loss, should you focus more on your diet or your exercise routine? All in all, you do need a balance of both. You must follow a diet and exercise in order to get the absolute best result. But when it comes down to which contributes more, you may be surprised as to what the answer is.

Simply put, exercise is the easy part...at least for most people. A majority of the population finds it much easier to get to the gym and break a sweat than to put down that piece of bread or stop themselves from another serving of dinner.

Exercise is always more favourable than dieting. Wouldn't it be nice if you could just exercise and eat whatever you want? Well, that's sure as heck not the case! Dieting contributes to about 90 per cent of fat loss, leaving only 10 per cent to exercise. This may come as a big surprise to you, but it is true. How come? Read more to find out why dieting has an advantage over exercise when it comes to weightloss.

You can't out-exercise a bad diet

This is such a popular phrase in the fitness world and it is probably one of the truest statements out there. Many people believe that if they work their butt off in the gym, that they can go home and eat what they want.

The main idea behind exercising is to burn calories. The unhealthy foods that you reward yourself with afterward are chockfull of unnecessary calories. Take this for example: You stop by the McDonald's drive-thru with some friends and splurge on a Big Mac. In the back of your head you're thinking 'I'll just go to the gym later'. Well, hold that thought and put the Big Mac down! In order to burn off a Big Mac, you would need to bust your butt in the gym for at least 90 minutes of full-on intense cardio, just to create a small calorie deficit.

This goes for all foods, not only Big Macs. In order to lose weight, you must burn more calories than you consume. If you have bad dietary habits, chances are that's not happening and that's the reason why you aren't losing weight. All the exercise in the world can't help a bad diet.

Illustration: Uttam Ghosh

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Diet or exercise: Which is more important for weightloss?

Public release date: 20-Jun-2012 [ | E-mail | Share ]

Contact: Alissa J. Cruz media@gastro.org 301-272-1603 American Gastroenterological Association

A six-food elimination diet significantly improves symptoms in adult patients with eosinophilic esophagitis (EoE), according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. In EoE, eosinophils and other inflammatory cells cause inflammation of the esophagus in response to an allergic stimulus. Previously thought to be a rare disease, EoE has become one of the most common causes for dysphagia (difficulty swallowing), heartburn and the sensation of "food stuck in the throat" in adults. Similar to children, this study has now shown that food allergens have a causative role in the majority of adults with EoE.

An elimination diet that identifies specic food triggers is an effective therapeutic alternative to corticosteroids for adults with EoE. Furthermore, the results of a reintroduction process in which these trigger foods are added back into a patient's diet support the fact that food antigens are driving this response; this provides new insight into the nature of the inammatory response in adult EoE.

"By first eliminating, then systematically reintroducing foods in our adult patients, we were able to identify the specic food triggers that caused their symptoms, such as heartburn, chest pain and difficulty swallowing, or the sensation of food being stuck in their throat," said Nirmala Gonsalves, MD, of Northwestern University and the lead author of this study. "Given the poor sensitivity of skin prick testing and lack of history of food allergy or intolerance, the six-food elimination diet with reintroduction is the only reliable method to date to identify food triggers in adult eosinophilic esophagitis and should allow us to better tailor diet to individual patients for long-term management." View a video abstract in which Dr. Gonsalves discusses her study findings.

A diet that eliminates all of the six most commonly allergenic foods (milk, soy, egg, wheat, peanuts/tree nuts and shellfish/fish) significantly improves symptoms and reduces esophageal tissue damage associated with EoE in adults. In fact, 78 percent of patients achieved greater than a 50 percent reduction in peak eosinophil (white blood cell) counts in their esophagus; dysphagia symptom scores improved signicantly after the elimination diet. Once trigger foods were reintroduced, all patients had recurrence of their symptoms within five days. These results suggest that EoE is likely the same disease in children and adults.

###

About the AGA Institute

The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include 17,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programs of the organization. http://www.gastro.org.

About Gastroenterology

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Food elimination diet identifies causes of difficulty swallowing and swelling of the throat

Public release date: 20-Jun-2012 [ | E-mail | Share ]

Contact: Jeremy Moore jeremy.moore@aacr.org 215-446-7109 American Association for Cancer Research

LAKE TAHOE, Nev. Study results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, held here June 18-21, strongly suggest that a diet high in fat and calories can hasten the development of pancreatic cancer in humans.

"Our results showed that in mice, a diet high in fat and calories led to obesity and metabolic disturbances such as insulin resistance that are seen in obese humans. It also greatly enhanced pancreatic inflammation and pancreatic cancer development," said Guido Eibl, M.D., an associate professor in the department of surgery at the David Geffen School of Medicine at the University of California, Los Angeles and a researcher at UCLA's Jonsson Comprehensive Cancer Center.

Human epidemiological studies have linked high fat intake and obesity to an increased risk of pancreatic cancer, but the mechanism driving this association has not been understood.

To understand the link, Eibl and his colleagues first tested the hypothesis that diet is linked to cancer. They fed a corn oil-based diet that had a high content of fat and calories to mice with a genetic mutation that caused them to develop pancreatic precancer. The same gene, KRAS, is mutated in the majority of human pancreatic cancers.

The results showed that 90 percent of the mice fed the special diet became obese, and all of these mice developed insulin resistance and inflammation in the pancreas. Both of these conditions can stimulate the growth of precancerous cells and cancer. These mice also developed significantly more advanced precancerous lesions than did mice fed a normal diet.

"This suggests that the high-fat, high-calorie diet accelerated pancreatic cancer development," said Eibl. "A KRAS mutation in the pancreas might not be sufficient to cause an individual to develop pancreatic cancer. It likely needs something in addition a secondary hit. Our study showed that a high-fat, high-calorie diet could provide an environmental secondary hit and trigger cancer development."

The researchers are now defining the role that inflammation produced by obesity plays in development of the cancer, and if agents such as antidiabetic drugs or fish oil can halt this disease process.

###

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High-fat/calorie diet accelerates development of pancreatic cancer

Johnny Depp Loss 2012 Johnny Depp Diet Programs - Isn't amazing how all of the celebrities you see have a celebrity diet plan for weight loss to maintain their weight. Some of them are shapely and healthy looking, and look good on camera. Others look like they haven't eaten in weeks, like they just got back from the famine in Ethiopia for a few weeks. Like they had been starving themselves to lose weight, and that is probably what they have been doing. You see it in all the tabloids, this person lost 100 pounds again, this one gained 100 pounds, and then lost 150 pounds. Some are not as dramatic; this one lost 40 pounds and is a television spokesperson, because the previous celebrity diet spokesperson gained the weight back. The fact is they may be starving themselves to lose weight, fasting like they are going through a famine.

"Click Here to Watch Weird VIDEO About The 7 Foods that KILL Abdominal Fat!"

Celebrities make dieting look so easy, don't they? One month they're on the cover of US Weekly for gaining too much weight and the next they're headlining the "sexiest beach bods" story. It is true that seriously overweight people can lose large amounts of fat in a quick amount of time, because of the large fat content in their cells. But those that are only a few pounds overweight, losing 40 pounds in a month, is not only starvation, it is malnutrition and can have serious side effects. Our body weight can fluctuate day to day and the best diets take the weight off gradually, the way it came on. If you lose a lot of weight in a short time, staying the same size will be impossible unless you follow a maintenance program for life. Good, sensible dieting means skill and will power combined. A lot of these celebrity diets or Hollywood diets are very bad for the body and the celebrities are thinking of the camera rather than their long term health. Researches indicate that individuals who indulge in a weight loss program by taking prepared meals end up losing an additional 31% weight as against those who cook their own meals. With help, losing weight is made easier and at times much faster as against doing it on your own.Diet delivery is gaining popularity in a big way as it is fairly affordable by even the common man, roughly around $20 a day with an increasing variety to choose from. A few of which include: Zone-compliant meal, low carbs plan, veggie meals, and gourmet too.

"Click Here to Watch Weird VIDEO About The 7 Foods that KILL Abdominal Fat!"

With the rapidly increasing epidemic of obesity and increasing BMI levels, there is an array of products and diet plan to aid in combating obesity. Celebrity slim diet, the basic idea is to educate people and not to depict food as an enemy. Like a lot of famous diets in Hollywood, if your body thinks you are starving, it is going to hold on to every calorie you take in to keep you from starving to death instead of burning them for energy. When you follow a properly balanced weight loss diet, your metabolism will hardly notice the decrease in calories and continue to burn fat it doesn't need to store. This is a more long-term weight loss strategy.

Celebrities do not have secrets about dieting. They are normal people like the rest of us but, unlike most of us, they have people working for them such as diet advisors and personal trainers. Celebrity diets involve a level of commitment and dedication which we struggle with. The best celebrity diets involve eating sensibly and limiting our calorie intake. Having these factors in mind will allow you to have safe and easy weight loss that will provide you with short term and long term consistent results.

"Click Here to Download The JohnnyDepp Diet Programs - Get a Great Body Like JohnnyDepp in Days!"

Originally posted here:
Johnny Depp Loss 2012 Johnny Depp Diet Programs

Courtesy of Diane Lazzari

Lucca the Belgian Tervuren's goal weight was 85 pounds, which meant she had to shed 15 pounds.

The running joke shared between Diane Lazzari and her husband, Dennis Green, was that their dog, an 8-year-old Belgian Tervuren, had a fully stocked refrigerator hidden in their Alameda backyard. Because regardless of what they fed her, Lucca kept gaining weight.

When our veterinarian shared her concern about Lucca's weight, which hovered between 98 and 101 pounds, I reassured her that we walked a vigorous 20 miles a week. A few extra pounds shouldn't be that big a deal, should it?

Then I read an article in The Chronicle that spelled out the "secret" formula for losing weight, human or canine: Eat less, exercise more and voila! A no-brainer, sure, but that article helped me realize that Lucca's extra weight really was a problem. Even a few additional pounds could lead to long-term health risks, such as hip dyspepsia and heart problems.

Dennis and I agreed that a serious diet was in order for our pudgy Belgian. A meeting with our vet established that Lucca's goal weight was 85 pounds with no more than 970 calories per day.

Lucca's first meal on her new regime was a real eye-opener. It was immediately evident that I had been overfeeding her, and by a lot. I used to fill her large metal bowl to the very top. Now, her 1 cup of measured food sat sadly at the bottom of her bowl, filling it only to about one quarter of what I had been giving her.

Lucca didn't have a refrigerator in the backyard. I was her refrigerator! Plus, Dennis and I were guilty of another no-no: sharing our people food with Lucca. We realized we had to cut back. My half scrambled egg in the morning became a teaspoon. For Dennis, leaving generous leftovers in his bowl changed to letting Lucca lick an empty bowl clean.

With monthly weigh-ins at the vet, we slowly started seeing progress. Two pounds one month, a pound another, sometimes none, but at least the numbers were moving down.

Unfortunately, these pound-saving techniques were not appreciated. I never realized how piercing the eyes of a Belgian could be while I was eating a hamburger. Or the effectiveness of a cold nose poking my face at 3 a.m. Initially, I thought the "cold nose poke" was Lucca's way of telling me she needed to go out. But I soon recognized ulterior motives were at stake when she continued walking past me, past the open door, and into the kitchen. Standing next to her empty bowl, she would look at it, and then back at me with an accusing stare. The message was all too clear and hard to ignore.

Read more here:
Diet a heart-tugger for Belgian Tervuren's owners

Angelina Jolie Loss 2012 AngelinaJolie Diet Program - Isn't amazing how all of the celebrities you see have a celebrity diet plan for weight loss to maintain their weight. Some of them are shapely and healthy looking, and look good on camera. Others look like they haven't eaten in weeks, like they just got back from the famine in Ethiopia for a few weeks. Like they had been starving themselves to lose weight, and that is probably what they have been doing. You see it in all the tabloids, this person lost 100 pounds again, this one gained 100 pounds, and then lost 150 pounds. Some are not as dramatic; this one lost 40 pounds and is a television spokesperson, because the previous celebrity diet spokesperson gained the weight back. The fact is they may be starving themselves to lose weight, fasting like they are going through a famine.

"Click Here to Watch Weird VIDEO About The 5 Foods that KILL Abdominal Fat!"

Celebrities make dieting look so easy, don't they? One month they're on the cover of US Weekly for gaining too much weight and the next they're headlining the "sexiest beach bods" story. It is true that seriously overweight people can lose large amounts of fat in a quick amount of time, because of the large fat content in their cells. But those that are only a few pounds overweight, losing 40 pounds in a month, is not only starvation, it is malnutrition and can have serious side effects. Our body weight can fluctuate day to day and the best diets take the weight off gradually, the way it came on. If you lose a lot of weight in a short time, staying the same size will be impossible unless you follow a maintenance program for life. Good, sensible dieting means skill and will power combined. A lot of these celebrity diets or Hollywood diets are very bad for the body and the celebrities are thinking of the camera rather than their long term health. Researches indicate that individuals who indulge in a weight loss program by taking prepared meals end up losing an additional 31% weight as against those who cook their own meals. With help, losing weight is made easier and at times much faster as against doing it on your own.Diet delivery is gaining popularity in a big way as it is fairly affordable by even the common man, roughly around $20 a day with an increasing variety to choose from. A few of which include: Zone-compliant meal, low carbs plan, veggie meals, and gourmet too.

"Click Here to Watch Weird VIDEO About The 5 Foods that KILL Abdominal Fat!"

With the rapidly increasing epidemic of obesity and increasing BMI levels, there is an array of products and diet plan to aid in combating obesity. Celebrity slim diet, the basic idea is to educate people and not to depict food as an enemy. Like a lot of famous diets in Hollywood, if your body thinks you are starving, it is going to hold on to every calorie you take in to keep you from starving to death instead of burning them for energy. When you follow a properly balanced weight loss diet, your metabolism will hardly notice the decrease in calories and continue to burn fat it doesn't need to store. This is a more long-term weight loss strategy.

Celebrities do not have secrets about dieting. They are normal people like the rest of us but, unlike most of us, they have people working for them such as diet advisors and personal trainers. Celebrity diets involve a level of commitment and dedication which we struggle with. The best celebrity diets involve eating sensibly and limiting our calorie intake. Having these factors in mind will allow you to have safe and easy weight loss that will provide you with short term and long term consistent results.

"Click Here to Download The AngelinaJolie Diet Programs - Get a Great Body Like AngelinaJolie in Days!"

Read more:
Angelina Jolie Loss 2012 AngelinaJolie Diet Program

ATLANTA--(BUSINESS WIRE)--

Designing a T-shirt is one thing, but designing a T-shirt that catches the eye of designers Zac Posen, Cynthia Rowley and LWren Scott and seeing it in the aisles of Target stores across the country? Now thats extraordinary.

Diet Coke and the Council of Fashion Designers of America (CFDA) today announced a partnership to give talented design students an extraordinary portfolio boost a chance to have their design featured at Target stores nationwide.

The three fashion-forward brands will celebrate up-and-coming talent through the Diet Coke Young Designer Challenge, a new competition searching for the next official Diet Coke T-shirt to inspire creative, extraordinary individuals everywhere.

The CFDA is an authoritative voice in the world of fashion and style, and we couldnt ask for a better partner for the Diet Coke Young Designer Challenge, said William White, Group Director Brand Diet Coke, Coca-Cola North America. With their support, one up-and-coming design student will have an extraordinary opportunity to launch his or her career in the world of fashion.

Adding to the excitement, the winning T-shirt design will be selected by some of the biggest names in fashion, including Vince Voron, associate Vice President, Strategic Design and Integrated Marketing Content, Coca-Cola North America, creative experts from Target and luminary designers Zac Posen, Cynthia Rowley and LWren Scott.

These leading style and fashion experts will select the winning design from a pool of 10 finalists, who will be chosen based on an online vote.

Through June 18, visitors to DietCoke.com/Design will be able to cast their vote for the T-shirt design they believe best represents the multi-dimensional and aspirational Diet Coke brand. The 20 designs in the running are the creations of the following design students, and were pre-selected from submissions by sophomores and juniors at CFDA partner colleges:

In addition to having his or her design available in Target stores nationwide this September, the grand-prize winner also will receive a $10,000 scholarship and a trip to New York City in September to experience the rush of a week of high fashion.

Diet Coke is an exciting and stylish brand, and we are pleased to be a partner in this unique design challenge, said Steven Kolb, CEO of the CFDA. Were always looking for ways to support the next generation of fashion designers, and this will be an amazing accomplishment for a student to put on a resume before he or she even graduates!

Continued here:
Diet Coke Partners with the Council of Fashion Designers of America to Celebrate Extraordinary Young Talent

Tammy Jackson swears she hasn't blown her nose in seven months. The credit, she said, goes to a change in diet.

Jackson and her boyfriend, Will Poole, started the Paleo diet in an effort to help Poole deal with Type I diabetes.

The Paleo diet eliminates processed foods and focuses on hunter-gatherer foods, much like cavemen would have eaten during the Paleolithic era. The philosophy is centered on the theory that our bodies respond best to food that is, and has been for thousands of years, naturally available to us.

Breads, cereals, potatoes, legumes and dairy products are prohibited in the strictest versions of the diet. Jackson and Poole have adapted their diets to include more meats, vegetables and nuts.

And eggs, Jackson said. "We eat a lot of eggs."

Health advantages

Jackson and Poole are convinced that the Paleo diet has improved their health.

Before the Paleo diet, Poole's food choices were adversely affecting his health.

"I didn't do a good job," he said. His idea of managing his diabetes well was, "I wasn't having to have to go to the ER on regular basis."

"Will's diet was a big concern of mine," Jackson said. "He ate anything. He would eat food that would spike his blood sugar and then treat it with insulin."

Read more from the original source:
Local Couple Improves Health Through Paleo Diet

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