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SAN DIEGO (AP) -- Arena Pharmaceuticals Inc. said Monday it transferred marketing rights for the diet pill Belviq to its partner Eisai Co. Ltd., which will market the drug in the U.S. and apply for approval in other North and South American countries.

Arena said it transferred the FDA application for the drug to the Japanese pharmaceutical company, which plans to submit it for approval in Mexico, Brazil, Canada and other countries.

The FDA approved Belviq in late June for adults who are obese or are overweight with at least one medical complication, such as diabetes or high cholesterol. It was the first FDA approval of a new drug for long-term weight loss in 13 years.

Arena's studies showed that patients taking Belviq, known generically as lorcaserin, had modest weight loss. On average patients lost 3 to 3.7 percent of their starting body weight over a year. About 47 percent of patients without diabetes lost at least 5 percent of their weight or more, which was enough to meet FDA standards for effectiveness.

Shares of Arena Pharmaceuticals fell 8 cents to $9.34 in morning trading.

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Arena transfers diet pill application to Eisai

GALVESTON, Texas, July 29 (UPI) -- The offspring of mothers on a low-protein diet are more likely to develop hypertension as adults, U.S. researchers say.

Drs. Haijun Gao, Uma Yallampalli and Chandra Yallampalli of the University of Texas Medical Branch at Galveston said in rats, the high maternal testosterone levels associated with a low-protein diet are caused by reduced activity of an enzyme that inactivates testosterone.

This increased testosterone reaches the fetus and increases the offspring's susceptibility to adulthood hypertension.

The researchers hypothesized the increased testosterone levels were caused either by increased activity of an enzyme that produces testosterone or by decreased activity of an enzyme that reduces testosterone, specifically Hsd17b2, which converts testosterone to a less potent androgen, androstenedione.

The team found that Hsd17b2 expression in rats was affected by protein restriction in two parts of the placenta.

The researchers propose the reduction in Hsd17b2 expression might allow more testosterone to reach the fetus and play a role in fetal programming of hypertension.

The findings are scheduled to be presented at the Society for the Study of Reproduction's annual meeting at State College, Pa.

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Mom-to-be diet tied to child hypertension

Your Diet Affects Your Grandchildren's DNA, Scientists Say

By: Christopher Wanjek, LiveScience Bad Medicine Columnist

Published: 07/27/2012 10:00 AM EDT on LiveScience

You are what you eat, the saying goes. And, according to two new genetic studies, you are what your mother, father, grandparents and great-grandparents ate, too.

Diet, be it poor or healthy, can so alter the nature of one's DNA that those changes can be passed on to the progeny. While this much has been speculated for years, researchers in two independent studies have found ways in which this likely is happening.

The findings, which involve epigenetics, may help explain the increased genetic risk that children face compared to their parents for diseases such as obesity and diabetes.

The punch line is that your poor dietary habits may be dooming your progeny, despite how healthy they will try to eat. [10 Worst Hereditary Conditions]

Epigenetics

Epigenetics refers to changes in gene expression from outside forces. Different from a mutation, epigenetic changes lie not in the DNA itself but rather in its surroundings -- the enzymes and other chemicals that orchestrate how a DNA molecule unwinds its various sections to make proteins or even new cells.

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Your diet affects your grandchildren's DNA, studies say

Seattle, WA (PRWEB) July 26, 2012

hCGTreatments / Diet Doc now offers weight loss pills that complement their natural weight management programs. With weight gain and obesity on the rise, most people are taking various precautions to stay healthy while others are taking drastic measures to fix the problem. Bariatric surgery is one of the drastic measures that is on the rise. Invasive surgery should be the absolute last resort for overweight or obese patients, due to its traumatic effects on the body, after exhausting all other methods of weight loss but most are starting to look to these invasive procedures are their only option.

hCGTreatments / Diet Docs weight management programs is a natural alternative to invasive surgery and offer the same drastic results. Their programs use hCG treatments, a natural hormone that works to balance the hormones, combined with a low-glycemic diet that is found to be suitable for people with any health condition. A diet plan is created for each patient by a nutritionist after a thorough health evaluation from a doctor and is guided by a weight loss coach throughout the program. Diet Docs patients are advised to supplement their diet plan with essential vitamins and minerals that are suited to their body type to optimize their bodies through the program.

Diet Docs newest addition the their line of weight loss products, however, are designed to make the diet easier by suppressing the appetite and burning belly fat. Abdominal, or visceral fat, actually plays a role in various types of diseases according to recent studies. In fact, a group of specialists that study the link between abdominal fat and disease called the International Chair on Cardio metabolic Risk held their third International Congress on Abdominal Obesity which present new research on topics relating to intra-abdominal, belly fat. Their researchers stated that it is critical to measure the waist circumference in patients with Type 2 diabetes because the greater waistline, the higher the risk will be of developing cardio-metabolic complications. Their studies also find the role between belly fat and inflammation, which is also a major factor for disease.

hCGTreatments / Diet Docs weight management programs aim to find the root of the problem and work to change it. Programs that promise fast weight loss solutions only provide a temporary fix to the problem. The hCG diet has been around for over 50 years and Diet Doc has worked to modernize the program to make it safer and more effective. Many of their patients claim to lose 14 pounds in two weeks, matching their results with those of the invasive procedures like the lap band or bariatric surgery. Diet Doc CEO, Julie Wright, states our weight management programs are safe and effective and work to change eating habits and body structure. These results are life-long and cannot be achieved through any surgery.

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hCGTreatments / Diet Doc Offers Weight Loss Pills to that Work to Suppress the Appetite and Burn Belly Fat

Young people aged 11-14 can eat a healthy Mediterranean diet and get all the zinc they need to help them grow, according to researchers.

The Mediterranean diet is high in vegetables, fruit and olive oil and low in meat

The research by Marta Mesias et al. published in the Public Health Nutrition Journal found that a diet high in cereals, legumes and veg and low in meat could provide adequate zinc amounts even though these foods have typically been thought to reduce the bioavailability of minerals.

Med diet meets needs

The Mediterranean diet has been proposed as one of the healthiest dietary models available, said the study.

Although a diet based on Mediterranean patterns is associated with factors which can affect Zn [zinc] absorption, such as high consumption of phytate, its consumption in adequate amounts allows Zn status to be maintained during adolescence.

The study found that a med diet could account for 76% of the Spanish recommended daily intake of zinc.

Although, the diet did not meet 100% of Spanish zinc standards, the researchers called Spains recommendations unnecessarily high.

Why zinc is important

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Med diet satisfies growing teens’ zinc requirements

The ancient Native Americans of the desert Southwest subsisted on a fiber-filled diet of prickly pear, yucca and flour ground from plant seeds, finds a new analysis of fossilized feces that may explain why modern Native Americans are so susceptible to Type II diabetes.

Thousands of years of incredibly fibrous foods, 20 to 30 times more fibrous than today's typical diet, with low impact on the blood sugar likely left this group vulnerable to the illness when richer Anglo foods made their way to North America, said study researcher Karl Reinhard, a professor of forensic sciences at the University of Nebraska-Lincoln.

"When we look at Native American dietary change within the 20th century, the more ancient traditions disappeared." Reinhard told LiveScience. "They were introduced to a whole new spectrum of foods like fry-bread, which has got a super-high glycemic index."

The glycemic index of a food is a measure of how fast its energy is absorbed into the bloodstream. It's measured on a scale of 1 to 100, with 1 being the slowest absorbing with the least effect on blood sugar. The native people who lived in the deserts of Arizona would have likely eaten traditional stews with glycemic indexes around 23, Reinhard found. Foods scoring lower than 55 are considered "low-GI" foods. [ 7 Perfect Survival Foods ]

Modern food and modern disease Members of Southwest Native American tribes are more susceptible than Caucasians to Type II diabetes, which happens when the body either doesn't produce enough insulin to break down sugar from food, or when the body's cells fail to recognize the insulin it does produce.

Researchers have long hypothesized that a "thrifty gene" (or, more likely, genes) acquired through feast and famine makes Native American populations more prone to this chronic disease. The idea is that people who were able to rapidly adapt to both lean times and times of plenty would have done better in ancient times. Today, the modern diet has rendered famine rare in the developed world, but the body continues to respond to times of plenty as if starvation is around the corner. Diabetes and obesity can result.

Reinhard and his colleagues now suggest that feast and famine may not be necessary for the "thrifty gene" hypothesis to make sense. Basically, Reinhard said, an extremely low-calorie, high-fiber diet made the ancient Native American gut a paragon of efficiency. With the arrival of whites, the diet changed faster than physiology could keep up with it. In other words, the digestive system didn't evolve for abundant, high-GI foods.

High-fiber diet To find solid evidence of what ancient Southwestern tribes actually ate, Reinhard turned to what he called "the most intimate residues from archaeological sites" fossilized poop. Known as coprolites, these fossils contain a record of their creator's most recent meals.

The researchers analyzed 25 coprolites from Antelope Cave in northwestern Arizona, a dwelling that was seasonally occupied for thousands of years. These particular coprolites (20 of which turned out to be human) date back to at least A.D. 1150 and earlier. The dates make the cave a perfect time to look at the transition from a total hunter-gatherer lifestyle to one supplemented by some agriculture, Reinhard said.

"It bridges two different dietary traditions, one which has been around for several thousands of years with one that was relatively newly introduced at the time the cave was occupied," he said.

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Ancient diet offers clues to diabetes

Miami, FL (PRWEB) July 24, 2012

hCGTreatments / Diet Doc hCG Diet and Weight Loss announce a new prescription strength dietary supplement line added to the rapid, doctor-supervised weight loss program.

Adequate vitamin and mineral intake plays an important role in optimal health and with much of the food grown in nutrient-depleted soil, people arent receiving the proper amount of vitamins and minerals from their vegetables and fruits. Because of this, dietary supplements have now become vital to peoples health and well-being.

A study on soil-depletion and its effects on crops conducted by Donald Davis at the University of Texas and published in the 2004 Journal of the American College of Nutrition revealed that reliable declines in the amount of protein, calcium, phosphorus, iron, riboflavin (vitamin B2) and vitamin C. Other studies reported by the Organic Consumers Association state that the average vitamin levels in vegetables dropped anywhere between 19 to 37 percent. With the declining state of crops grown conventionally and organically, supplements are especially needed to support overall health and weight loss as well. A deficiency in key nutrients can lead to weight gain and obesity amongst a number of other heath conditions.

hCGTreatments / Diet Doc now offers their new line of prescription-strength supplements to their patients. Their successful hCG weight loss programs make these key supplements a portion of their overall diet plan. The program uses hCG hormone treatment for only a fraction of the time and also follows a ketogenic diet through the duration of the program which basically consists of green leafy vegetables, lean protein, medium-chain triglyceride fat and supplemented with suggested vitamins and minerals. Each person varies with what their body needs so Diet Doc also created a comprehensive health assessment questionnaire to determine what each patients health strengths and weakness are and make suggestions from there. This health assessment is offered as a free option to their patients and includes a comprehensive report that details the cause and effect of their health conditions and suggested vitamins. This report is only used as a tool and advises all patients to consult with their physician before taking any supplement.

hCGTreatments / Diet Docs weight loss programs offer more than just temporary weight loss solutions. Their programs work to change the bodys composition as well as change eating behaviors. They strive to help their patients make permanent health changes by finding the underlying cause of weight gain and shedding light on it. And with their new line of prescription-strength supplements they offer, their program is sure to meet the nutritional needs that most people are now lacking.

hCGTreatments is a doctor designed and managed, nationwide weight loss program for extreme (fast) weight loss that is sustainable long-term.

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Diet Doc Announces New Line of Prescription-Strength Dietary Supplements that Complements the hCGTreatments Weight ...

Appetite for Health

Sometimes when asked what I do for a living, my response is: "I tell people to eat more vegetables." Of course there is much more to what I do as a nutritionist and much more to healthy eating than that but consuming more vegetables is one of the most important steps in improving the quality of your diet. For all the excesses in the current American food culturetoo much sodium, saturated fat, and calories, for examplefew people are over consuming veggies. In fact, surveys show that 68 percent of Americans do not meet the minimal guidelines for vegetable consumption (three servings daily). Only 26 percent of the nation's adults eat vegetables three or more times a day and just 23 percent of meals include a vegetable.

This is despite clear evidence that vegetables can improve our chances of better health. Studies show that a diet rich in vegetables may reduce risk for heart disease, diabetes, and certain types of cancers. Vegetables high in potassium may lower blood pressure.

Veggies are also one of your best allies in the battle against "the bulge." Because they are lower in calories per cup, when you eat them in place of other higher-calorie foods you can lower your total calorie intake. Research shows that in addition, their high water and fiber content can help keep you fuller for longer, reducing the likelihood of overeating.

Given their importance to your overall health, eating more veggies should be a top priority. Try these tips to ensure you're getting enough:

1. Start a garden. Over the years, I have found that one of the best ways to get people excited about eating vegetables is to have them grow their own. Research studies have supported my observation: Young or old, gardeners have been found to consume more veggies than non-gardeners. The simple act of gardening connects us to the earth, the soil, and the food we eat. Few can resist nature's bounty when it's springing up right in your own yard. Plus there is nothing like the taste and freshness of veggies straight from the garden.

Don't have space for a garden? Many local urban centers have thriving community gardens. Find one in your area and ask to volunteer.

2. Veggies for breakfast . For breakfast? You bet! Your morning meal is the perfect place to get a jumpstart on your daily veggie servings. Stuff an omelet with broccoli, spinach, peppers, asparagus, or any other vegetable that suits your taste buds.

Short on time? Scramble your eggs with a half-cup of salsa. Roll it into a whole-grain tortilla and take it with you as you fly out the door.

3. Soups. Add more flavor and nutrition to your favorite soups with veggies. Many homemade soups already contain a nice amount of vegetables, but you can bump up the veggie servings in canned soups too. I love adding carrots to chicken noodle soup, and edamame or green beans to minestrone. Just add the raw or frozen vegetables while you are cooking or heating the soup. And don't forget that leafy greens such as kale, Swiss chard, and spinach make great additions too.

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5 Ways to Sneak More Veggies Into Your Diet

Who hasn't thrown their diet rules out the window on the weekend or gone crazy with a super-rich and gooey chocolate dessert? Of course it's fine to splurge every once in a while, but over time these seemingly minor violationsin addition to some other not-so-small diet sinscan add up to a big number on your scale.

To the rescue: our guide to the most common diet mistakes that even smart women makeand straightforward advice on how to fix them.

1. Caution: Gulping down food

If you make a habit of rushing through meals, you could end up eating more than you intend toor even realize. Your brain takes at least 15 minutes to register fullness, so if you shovel food into your mouth at a frantic pace, your stomach could become overstuffed before you actually know you've had enough.

The fix: Make a conscious effort to savor the flavor. Try to dedicate more chews to every mouthful. You can also place your fork on your plate between bites and pick it up again only after you've swallowed. This will double the time it takes to eat. The payoff: In a recent study from the University of Rhode Island in Kingston, women were told to eat a pasta dish slowly by pausing between bites and chewing each mouthful 15 to 20 times. As a result they consumed about 70 fewer calories during the meal than when they consumed the same dish at a fast pace. __________________________________________________

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Avoid These Diet Mistakes

Some children are picky eaters, some are obese and some are both. But none of Onile Ngozi's three children falls into those categories.

Ngozi, 45, of St. Louis, became a vegan 18 years ago and has raised her children, ages, 7, 17 and 19, on a vegan diet.

Vegetarians eliminate meat, poultry and fish from their diet but eat eggs and dairy products. Vegans go a step further. Their diets are plant-based and don't allow for dairy, eggs or any animal products.

Yes, Ngozi admits, some people think she's crazy.

"They say, 'What do you mean you're not feeding your children any meat? What do you mean you're not giving them dairy? They need iron. They need protein.' They're amazed that they're so healthy, active and intelligent. And they're amazed that they want food that's good for them."

Earlier this year, the children's book "Vegan is Love: Having Heart and Taking Action," by Ruby Roth, a vegan mother, hit store shelves. Reaction to it was mixed. Many meat-eaters found it preachy and graphic from an animal rights standpoint. And some health experts worried that children eating such a diet wouldn't get proper nutrition.

Nicole German, a dietitian/blogger in Atlanta, wrote that "it could easily scare a young child into eating vegan, and, without proper guidance, that child could become malnourished."

Vegans say the opposite is true.

Lee Ferrenbach, a sales associate at Golden Grocer Natural Foods in the Central West End and a vegan, believes babies prefer a vegan diet.

"If you put meat and fruit in front of a baby, they'll choose the fruit," he says.

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Vegans tout their diet

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