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Dec 31

Testosterone – Lab Tests Online

Sources Used in Current Review

2016 review performed by Donald Walt Chandler, Exec. Director Endocrine Sciences, LabCorp.

S. Bhasin, G.R. Cunningham, F.J. Hayes, Task Force, Endocrine Society, et al. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metabolism, 6 (2010) 2536259.

Centers for Disease Control Hormone Standardization website(HoST). Available online at http://www.cdc.gov/labstandards/hs_standardization.html. Accessed February 2016.

W. Rosner, R.J. Auchus, R. Azziz, et al. Position statement: utility, limitations, and pitfalls in measuring testosterone: an endocrine society position statement. J Clin Endocrinol Metabolism, 92 (2007), Pp. 405413.

Sartorius G, Spasevska S, Idan A, Turner L, Forbes E, Zamojska A, Allan CA, Ly LP, Conway AJ, McLachlan RI, Handelsman DJ. Serum testosterone, dihydrotestosterone and estradiol concentrations in older men self-reporting very good health: the healthy man study. Clin Endocrinol (Oxf). 2012 Nov;77(5):755-63. doi: 10.1111/j.1365-2265.2012.04432.

Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R, Pfeifer M, Pignatelli D & Pugeat M . B O Yildiz on behalf of the ESE PCOS Special Interest Group. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. European Journal of Endocrinology 2014 171 P1P29. (doi:10.1530/EJE-14-0253).

Sources Used in Previous Reviews

Clinical Chemistry: Theory, Analysis, Correlation. 3rd Edition. Lawrence A. Kaplan and Amadeo J. Pesce, St. Louis, MO. Mosby, 1996.

Clinical Chemistry: Principles, Procedures, Correlations. Michael L. Bishop, Janet L. Duben-Engelkirk, Edward P. Fody. Lipincott Williams & Wilkins, 4th Edition.

The Gale Encyclopedia of Childhood and Adolescence. Testosterone. Available online at http://www.findarticles.com/p/articles/mi_g2602.

Laurence M. Demers, PhD. Distinguished Professor of Pathology and Medicine, The Pennsylvania State University College of Medicine, The M. S. Hershey Medical Center, Hershey, PA.

Pagana K, Pagana T. Mosby’s Manual of Diagnostic and Laboratory Tests. 3rd Edition, St. Louis: Mosby Elsevier; 2006, Pp 481-484.

(January 2006) The Hormone Foundation. Low Testosterone and Men’s Health. PDF available for download at http://www.hormone.org/Resources/Reproduction/upload/bilingual_Testosterone.pdf. Accessed January 2009.

(January 2008) Eugster E, Palmert M, eds. The Hormone Foundation. Precocious Puberty. PDF available for download at http://www.hormone.org/Resources/Growth/upload/bilingual_precocious_puberty.pdf. Accessed January 2009.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER, Bruns DE, eds. St. Louis: Elsevier Saunders; 2006.

(March 18, 2008) Holt E. MedlinePlus Medical Encyclopedia. Testosterone. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003707.htm. Accessed January 2009.

(December 9, 2008) Mayo Clinic. Male hypogonadism. Available online at http://www.mayoclinic.com/health/male-hypogonadism/DS00300. Accessed January 2009.

(June 7, 2012) Kaplowitz. Precocious Puberty. Medscape Reference article. Available online at http://emedicine.medscape.com/article/924002-overview. Accessed November 2012.

(June 6, 2012) Kemp S. Hypogonadism. Medscape Reference. Available online at http://emedicine.medscape.com/article/922038-overview.Accessed November 2012.

(October 30, 2012) Lucidi R. Polycystic Ovarian Syndrome. Medscape Reference. Available online at http://emedicine.medscape.com/article/256806-overview. Accessed November 2012.

The Endocrine Society’s Clinical Guidelines. Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes. J Clin Endocrinol MetabJune 2010, 95(6):25362559. PDF available for download at http://www.endo-society.org/guidelines/final/upload/FINAL-Androgens-in-Men-Standalone.pdf.Accessed November 2012.

Harrison’s Principles of Internal Medicine, 18ed, Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, Eds., McGraw-Hill. (2012) Chapters 49 & 346.

Original post:
Testosterone – Lab Tests Online


Dec 29

Testosterone : The Test | Testosterone Test – labtestsonline.org

Sources Used in Current Review

2016 review performed by Donald Walt Chandler, Exec. Director Endocrine Sciences, LabCorp.

S. Bhasin, G.R. Cunningham, F.J. Hayes, Task Force, Endocrine Society, et al. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metabolism, 6 (2010) 2536259.

Centers for Disease Control Hormone Standardization website(HoST). Available online at http://www.cdc.gov/labstandards/hs_standardization.html. Accessed February 2016.

W. Rosner, R.J. Auchus, R. Azziz, et al. Position statement: utility, limitations, and pitfalls in measuring testosterone: an endocrine society position statement. J Clin Endocrinol Metabolism, 92 (2007), Pp. 405413.

Sartorius G, Spasevska S, Idan A, Turner L, Forbes E, Zamojska A, Allan CA, Ly LP, Conway AJ, McLachlan RI, Handelsman DJ. Serum testosterone, dihydrotestosterone and estradiol concentrations in older men self-reporting very good health: the healthy man study. Clin Endocrinol (Oxf). 2012 Nov;77(5):755-63. doi: 10.1111/j.1365-2265.2012.04432.

Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R, Pfeifer M, Pignatelli D & Pugeat M . B O Yildiz on behalf of the ESE PCOS Special Interest Group. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. European Journal of Endocrinology 2014 171 P1P29. (doi:10.1530/EJE-14-0253).

Sources Used in Previous Reviews

Clinical Chemistry: Theory, Analysis, Correlation. 3rd Edition. Lawrence A. Kaplan and Amadeo J. Pesce, St. Louis, MO. Mosby, 1996.

Clinical Chemistry: Principles, Procedures, Correlations. Michael L. Bishop, Janet L. Duben-Engelkirk, Edward P. Fody. Lipincott Williams & Wilkins, 4th Edition.

The Gale Encyclopedia of Childhood and Adolescence. Testosterone. Available online at http://www.findarticles.com/p/articles/mi_g2602.

Laurence M. Demers, PhD. Distinguished Professor of Pathology and Medicine, The Pennsylvania State University College of Medicine, The M. S. Hershey Medical Center, Hershey, PA.

Pagana K, Pagana T. Mosby’s Manual of Diagnostic and Laboratory Tests. 3rd Edition, St. Louis: Mosby Elsevier; 2006, Pp 481-484.

(January 2006) The Hormone Foundation. Low Testosterone and Men’s Health. PDF available for download at http://www.hormone.org/Resources/Reproduction/upload/bilingual_Testosterone.pdf. Accessed January 2009.

(January 2008) Eugster E, Palmert M, eds. The Hormone Foundation. Precocious Puberty. PDF available for download at http://www.hormone.org/Resources/Growth/upload/bilingual_precocious_puberty.pdf. Accessed January 2009.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER, Bruns DE, eds. St. Louis: Elsevier Saunders; 2006.

(March 18, 2008) Holt E. MedlinePlus Medical Encyclopedia. Testosterone. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003707.htm. Accessed January 2009.

(December 9, 2008) Mayo Clinic. Male hypogonadism. Available online at http://www.mayoclinic.com/health/male-hypogonadism/DS00300. Accessed January 2009.

(June 7, 2012) Kaplowitz. Precocious Puberty. Medscape Reference article. Available online at http://emedicine.medscape.com/article/924002-overview. Accessed November 2012.

(June 6, 2012) Kemp S. Hypogonadism. Medscape Reference. Available online at http://emedicine.medscape.com/article/922038-overview.Accessed November 2012.

(October 30, 2012) Lucidi R. Polycystic Ovarian Syndrome. Medscape Reference. Available online at http://emedicine.medscape.com/article/256806-overview. Accessed November 2012.

The Endocrine Society’s Clinical Guidelines. Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes. J Clin Endocrinol MetabJune 2010, 95(6):25362559. PDF available for download at http://www.endo-society.org/guidelines/final/upload/FINAL-Androgens-in-Men-Standalone.pdf.Accessed November 2012.

Harrison’s Principles of Internal Medicine, 18ed, Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, Eds., McGraw-Hill. (2012) Chapters 49 & 346.

See original here:
Testosterone : The Test | Testosterone Test – labtestsonline.org


Dec 17

VTrex – Testosterone Boosting Male Enhancement | Free Sample

VTrex Male Enhancement Pills

The answer to the inevitable decline of testosterone levels is VTrex! After you hit 25 years old your days of natural peak testosterone are over. Each passing year means you are losing another 1%-3%. By the time you reach 50 you could be down by as little as 25% from your peak level. Low T-Levels means you will experience many telltale signs of becoming an aging male. These signs include mental and physical fatigue, brain fog and moodiness. Other symptoms include poor sex drive and performance. You may also experience decreased muscle and increased body fat.

All and all, the decrease of your testosterone levels is a bad thing. If you are trying to build muscle then you can expect little gains. This can have you skipping work outs do frustration, low energy and lack of motivation. Needless to say, diminishing T-levels can significantly impact a mans lifestyle. Though this is an inevitable part of aging it doesnt mean you have to put up with it. Going against the laws of nature and becoming a superhuman alpha male is now possible. Supercharge your T-levels with the powerful formulation of testosterone boosting ingredients provided by VTrex!

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Want to enhance your sexual drive and performance? Need to improve your strength and stamina? Do you want to boost your testosterone and feel like a real man? Claim your VTrex free trial now! Experience the sports nutrition and testosterone boosting power of this natural formula. Get your best performance in the bedroom and the gym with your free trial bottle of VTrex. Order now and become the alpha male and sexual God that you deserve to be!

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VTrex – Testosterone Boosting Male Enhancement | Free Sample


Nov 17

Testosterone | Hormone Health Network

October 2017

Download PDFs English

EditorsPuneet Singh Arora, MD

Additional Resources MedlinePlus

Testosterone is the main sex hormone found in men. It controls male physical features. The testes (testicles) make testosterone. Women have testosterone too but in much smaller amounts than in men.

Why is testosterone important for boys and men?

Testosterone helps bring on the physical changes that turn a boy into a man. This time of life is called puberty. Changes include:

Men also need normal amounts of this hormone to make sperm and be able to have children.

How does testosterone work?

The brain and pituitary gland, a small gland at the base of the brain, control production of testosterone by the testes. From there, testosterone moves through our blood to do its work.

Your testosterone levels change from hour to hour. They tend to be highest in the morning and lowest at night.

Testosterone levels are highest by age 20 to 30 and slowly go down after age 30 to 35.

What can go wrong with testosterone levels?

For many reasons, testosterone can becomeand staytoo low. Less often, testosterone levels can become too high. When this hormone is not in balance, health problems can result. Ask your doctor if you should get your testosterone level checked if you have any of the problems mentioned below. You can get treatment to fix hormone problems.

Early symptoms (changes you feel) and signs (abnormalities that your doctor finds) of low testosterone in men include:

Later, low testosterone can lead to decreased muscle and bone strength, less energy, and lower fertility.

Some things can temporarily lower testosterone, for instance, too much exercise, poor nutrition, or serious illness. Living a healthy lifestyle with regular exercise and a good diet helps maintain normal testosterone levels.

When young boys have too much testosterone, they can start puberty too early (before age 9). Some rare conditions, such as certain types of tumors, cause boys to make testosterone earlier than normal.

Young boys also can have too much testosterone if they touch testosterone gel that an adult man is using for treatment

How do you know what your testosterone level is?

To measure your testosterone level, your doctor can order a blood test. The test should be done in the morning between 7:00 and 10:00. If the result is not normal, you should repeat the test to make sure of the result. In healthy men, testosterone levels can change a lot from day to day, so a second test could be normal.

WORDS TO KNOW

androgen(AN-druh-jenn):a male sex hormone, such as testosterone.

endocrinologist(EN-doh-krih-NOLL-uh-jist):

a doctor who treats people who have hormone problems.

hormone (HOR-mohn):a chemical made in a gland in one part of the body. The hormone travels through the blood to another part of the body, where it helps other cells do their job.

hypogonadism (HI-po-GO-nad-iz-um):a low testosterone level or sperm count, or both.

sex hormone:a hormone that affects and is made by the reproductive (sex) organs. It is responsible for secondary sex traits, such as facial hair in men.

Questions to ask your doctor

Read more:
Testosterone | Hormone Health Network


Nov 10

Testosterone – webmd.com

Test Overview

A testosterone test checks the level of this male hormone (androgen) in the blood. Testosterone affects sexual features and development. In men, it is made in large amounts by the testicles . In both men and women, testosterone is made in small amounts by the adrenal glands , and in women, by the ovaries .

The pituitary gland controls the level of testosterone in the body. When the testosterone level is low, the pituitary gland releases a hormone called luteinizing hormone (LH). This hormone tells the testicles to make more testosterone.

Before puberty, the testosterone level in boys is normally low. Testosterone increases during puberty. This causes boys to develop a deeper voice, get bigger muscles, make sperm , and get facial and body hair. The level of testosterone is the highest around age 40, then gradually becomes less in older men.

In women, the ovaries account for half of the testosterone in the body. Women have a much smaller amount of testosterone in their bodies compared to men. But testosterone plays an important role throughout the body in both men and women. It affects the brain, bone and muscle mass, fat distribution, the vascular system, energy levels, genital tissues, and sexual functioning.

Most of the testosterone in the blood is bound to a protein called sex hormone binding globulin (SHBG). Testosterone that is not bound (“free” testosterone) may be checked if a man or a woman is having sexual problems. Free testosterone also may be tested for a person who has a condition that can change SHBG levels, such as hyperthyroidism or some types of kidney diseases.

Total testosterone levels vary throughout the day. They are usually highest in the morning and lowest in the evening.

A testosterone test is done to:

You do not need to do anything before you have this test. Your doctor may want you to do a morning blood test because testosterone levels are highest between 7 a.m. and 9 a.m.

The health professional taking a sample of blood will:

The blood sample is taken from a vein in your arm. An elastic band is wrapped around your upper arm. It may feel tight. You may feel nothing at all from the needle, or you may feel a quick sting or pinch.

There is very little chance of a problem from having a blood sample taken from a vein.

A testosterone test checks the level of this male hormone (androgen) in the blood.

The normal values listed here-called a reference range-are just a guide. These ranges vary from lab to lab, and your lab may have a different range for what’s normal. Your lab report should contain the range your lab uses. Also, your doctor will evaluate your results based on your health and other factors. This means that a value that falls outside the normal values listed here may still be normal for you or your lab.

Your doctor will have your test results in a few days.

Men

270-1070 ng/dL (9-38 nmol/L)

Women

15-70 ng/dL (0.52-2.4 nmol/L)

Children (depends on sex and age at puberty)

2-20 ng/dL or 0.07-0.7 nmol/L

The testosterone level for a postmenopausal woman is about half the normal level for a healthy, nonpregnant woman. And a pregnant woman will have 3 to 4 times the amount of testosterone compared to a healthy, nonpregnant woman.

Men

50-210 pg/mL (174-729 pmol/L)

Women

Reasons you may not be able to have the test or why the results may not be helpful include:

To learn more, see:

Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.

Chernecky CC, Berger BJ (2008). Laboratory Tests and Diagnostic Procedures, 5th ed. St. Louis: Saunders.

Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.

Pagana KD, Pagana TJ (2010). Mosbys Manual of Diagnostic and Laboratory Tests, 4th ed. St. Louis: Mosby Elsevier.

ByHealthwise StaffPrimary Medical ReviewerE. Gregory Thompson, MD – Internal MedicineSpecialist Medical ReviewerAlan C. Dalkin, MD – Endocrinology

Current as ofNovember 20, 2015

WebMD Medical Reference from Healthwise

The rest is here:
Testosterone – webmd.com


Oct 19

Testim VS Androgel – Testosterone Replacement Therapy

The two major testosterone gel brands are Testim and Androgel. They are very similar and generally prescribed interchangeably, but sometimes insurance wont cover one or the other. Often, I hear that they wont cover Testim and people want to know if Androgel is just as good. So here is a general guide to choosing if you are lucky enough to have the choice which one is right for you.

Testim Vs AndrogelI would try whichever your insurance covers first. If your insurance covers both medications, try whichever one has coupons or kickbacks. Ive heard people say they didnt pay any/much for Testim for the first year because the company (Auxilium) that markets the drug has a financial assistance program available for the first year.

Now that price and availability are out of the way, lets deal with smell: Testim smells. Some people think it smells good, and some cant stand it. Personally, I like it and my wife likes it. Ive found that women ask me what cologne Im wearing, and mention that they like it too. Still, if you or your wife dont like the smell of something you have to put on every day, that would be a deal-breaker. So try out a tube and see what you and, if applicable, your partner thinks about the Testim scent. Androgel doesnt have much of a smell at all.

Testim is sticky. Androgel goes on much like that hand-sanitizer stuff, while Testim seems to remain stickier longer. Some say this is why Testim seems to work better for them: Because it stays on the skin and soaks in better. These personal statements of efficacy cant be relied on as empirical data, however. But the fact that you can feel it on your skin longer, does bring up a question about Testim gel Vs Androgel: Does it take longer to soak in and, if so, does that increase the exposure time I have to worry about when it comes to my wife and children? The short answer is: NO. In-fact, according to US National Library of Medicines website, the wait-time for AndrogGel is much longer:

You should not shower, bathe, swim, or wash the place where you applied the medication for at least 2 hours after you apply Testim gel or at least 5-6 hours after you apply AndroGel .

WasteTestim comes in little single-use tubes so you go through more of them and it generates more waste. If you are eco-minded this may factor into your decision. Androgel comes in a dispenser with a little pump on it (like soap) so there is less waste.

But the real question when considering AndroGel Vs Testim is: Which works better? Which is the best? Which testosterone topical gel is going to get my testosterone levels on track fast, keep my levels steady, and keep me there for the long term since Ill be taking this stuff for many years to come? As you might guess, both brands have their fans. Personally, I like Testim. And here is a study to back up my personal preference:

Efficacy of changing testosterone gel preparations (Androgel or Testim) among suboptimally responsive hypogonadal men.Grober ED, Khera M, Soni SD, Espinoza MG, Lipshultz LI.Division of Urology, Mount Sinai Hospital and Womens College Hospital, University of Toronto, Toronto, ON, Canada.Summary of the study:

A change in testosterone gel preparation among initially unresponsive hypogonadal men is justified prior to abandoning or considering more invasive TRT. Changing from Androgel to Testim offers hypogonadal men the potential for improved clinical and biochemical responsiveness. Changing from Testim to Androgel is indicated to eliminate or minimize unwanted side effects.

Note: This study was done to find out if switching brands would help men who were unresponsive to one brand or the other.

More important to me than such a study is to find out from others who have been on TRT for more than a year, preferably several years or more, and hear about their experiences with both or either drug. Please comment below with your own experiences.

I am inclined toward a weekly injection over a daily application, but what does ones rear-end feel like after being used as a pin-cushion for decades? I dunno any bodybuilders out there want to elaborate on that?

Read the original here:
Testim VS Androgel – Testosterone Replacement Therapy


Oct 1

Testosterone Deficiency, Erectile Dysfunction, and …

Testosterone is a hormone produced by the testicles and is responsible for the proper development of male sexual characteristics. Testosterone is also important for maintaining muscle bulk, adequate levels of red blood cells, bone growth, a sense of well-being, and sexual function.

Inadequate production of testosterone is not a common cause of erectile dysfunction; however, when ED does occur due to decreased testosterone production, testosterone replacement therapy may improve the problem.

As a man ages, the amount of testosterone in his body naturally gradually declines. This decline starts after age 30 and continues throughout life. Some causes of low testosterone levels are due to:

Without adequate testosterone, a man may lose his sex drive, experience erectile dysfunction, feel depressed, have a decreased sense of well-being, and have difficulty concentrating.

Low testosterone can cause the following physical changes:

The only accurate way to detect the condition is to have your doctor measure the amount of testosterone in your blood. Because testosterone levels fluctuate throughout the day, several measurements will need to be taken to detect a deficiency. Doctors prefer, if possible, to test levels early in the morning, when testosterone levels are highest.

Note: Testosterone should only be used by men who have clinical signs and symptoms AND medically documented low testosterone levels.

Testosterone deficiency can be treated by:

Each of these options provides adequate levels of hormone replacement; however, they all have different advantages and disadvantages. Talk to your doctor to see which approach is right for you.

Men who have prostate cancer or breast cancer should not take testosterone replacement therapy. Nor should men who have severe urinary tract problems, untreated severe sleep apnea or uncontrolled heart failure. All men considering testosterone replacement therapy should undergo a thorough prostate cancer screening — a rectal exam and PSA test — prior to starting this therapy.

In general, testosterone replacement therapy is safe. It is associated with some side effects, including:

Laboratory abnormalities that can occur with hormone replacement include:

If you are taking hormone replacement therapy, regular follow-up appointments with your doctor are important.

Like any other medication, directions for administering testosterone should be followed exactly as your doctor orders. If you are unsure or have any questions about testosterone replacement therapy, ask your doctor.

SOURCE:

Get-Back-On-Track.com.

The Hormone Foundation.

News release, FDA.

See the original post here:
Testosterone Deficiency, Erectile Dysfunction, and …


Sep 28

How Long Does Testosterone (TRT) Take To Work?

We are frequently asked how long patients will have to wait before they start feeling better after starting testosterone replacement therapy. The best answer can get a little complicated, but there are definitely some factors that we have identified which help to predict success.

This video is a rapid fire explanation of testosterone replacement therapy (TRT). It will provide a great foundation for those seeking to learn more about Low T treatments like testosterone gels, pellets, or injections.

First of all, it is important to be looking for the right things. Knowing what the real symptoms of Low T areis extremely important.

Making sure that your treatment is medically supervised by providers who know The Side Effects of TRT well, and being consistent with the prescribed therapy, plays the biggest role in how quickly you will respond.

Keep in mind that people are not cookie cutter clones of one another either each individual is different, and your response will be too.

Understanding that there is no hard fast rule here, most patients feel significant improvement in symptoms within 4-6 weeks of starting treatment for Low T.

It is common for symptoms like low sex drive and difficulty maintaining sleep to respond sooner. On the other hand, factors like obesity, chronic illness, or medications can make ones response slower or more subtle at first.

It has been our experience that failure to respond to treatment (when the person is committed to staying consistent with appointments and recommendations) is very rare.

Especially with injections, response to therapy has nothing to do withwaiting for your testosterone levels to come up.

If properly managed, your levels can be normalized with the first dose, possibly in just a few days.

The lag in symptomatic response represents the time it takes for your body to achieve balance. Making numbers look better is one thing carefully balancing hormonal shifts and the potential side effects is where the art of medicine becomes crucial.

Below you will find some references to what the studies say on the subject, but ultimately, we have found the following to be true:

In the study titled, Timetable of effects of testosterone administration to hypogonadal men on variables of sex and mood (Jockenhovel, Minnemann, et al, The Aging Male, December 2009: 12 (4): 113-118), 40 men with testosterone levels definitively established as low were evaluated for timing of response to therapy.

Specifically, the researchers wanted to know how long it took for men to experience improvement in total numbers of erections and ejaculations, indicators of improved libido such as sexual thoughts and fantasies, and perceived sexual interest/desire and satisfaction with their sex lives.

Additionally, several psychosocial parameters were measured looking for changes such as levels of agitation, aggression, depression, listlessness (avoidance of activity), sociability, and activation.

Activation, by the way, is defined by Britannica Online Encyclopedia as the stimulation of the cerebral cortex into a state of general wakefulness, or attention.

Essentially, you can think of activation as concentration and alertness in this context.

It is important to note that this study only evaluated patients at three-week intervals, so any symptomatic change occurring before that point could not be documented. For the psychosocial effects assessed by the study, anxiety levels, aggression, and sociability all showed significant response at three weeks after the start of therapy.

The scoring for all three of these parameters continued to improve over the next 9 weeks, all plateauing around week 12.

When considering aggression, it is worth noting that when a mans testosterone level is normal, he is usually appropriately aggressive. A total lack of aggression is most often a social liability and can sometimes lead to missed opportunities, especially in the workplace.

On the other hand, roid rage, which is frequently associated with anabolic steroid abuse (and the supraphysiologic levels that ensue), occurs in the setting of extremely elevated levels of testosterone.

This is not something seen when TRT is managed responsibly and safely. The goal should always be to improve symptoms while improving testosterone levels from deficient levels to normal ones.

Depression and listlessness both decreased substantially by week 6 and remained fairly steady thereafter. For agitation and activation, both of these measurements showed sharp improvements at 9 weeks and stayed relatively stable thereafter.

This study evaluated sexual function by tracking the number of spontaneous erections, total erections, and ejaculations reported by men. Other aspects that were quantified were frequency of sexual thoughts/fantasy, intensity of sexual desire, and overall satisfaction with sex life.

For the three measurements of sexual function, men reported positive changes for all at their 3-week evaluation. The number of spontaneous and total erections, as well as the number of ejaculations, increased to stable levels between weeks 12 to 21.

Sexual thoughts and fantasy rose considerably by week three and remained at levels approximately double initial scores thereafter. Sexual desire followed a similar track, reaching a plateau around the 9th week.

Finally, satisfaction with sex life rose sharply by 3rd week and continued on a dramatic rise through week-30 when the study concluded.

As the study says, Treatment of hypogonadal men (men with Low T) with testosterone is rewarding, for the patients as well as the physician.

The patient experiences, to his satisfaction, profound changes in his physical appearance and his mental make-up.

The attending physician observes the changes the patient undergoes and rarely fails to be fascinated by the multitude of functions testosterone appears to have in [the] process of masculinization in the broadest sense. The take home points are these.

The researchers behind this journal article looked only at sexual functioning and mood. There is often much more that is negatively impacted by Low T.

If you have questions or comments please take the time to contact us, we would be happy to sit down with you and discuss how testosterone replacement therapy can improve your quality of life.

Read the original:
How Long Does Testosterone (TRT) Take To Work?


Sep 23

Testosterone(androgen) – WebMD

Test Overview

A testosterone test checks the level of this male hormone (androgen) in the blood. Testosterone affects sexual features and development. In men, it is made in large amounts by the testicles . In both men and women, testosterone is made in small amounts by the adrenal glands , and in women, by the ovaries .

The pituitary gland controls the level of testosterone in the body. When the testosterone level is low, the pituitary gland releases a hormone called luteinizing hormone (LH). This hormone tells the testicles to make more testosterone.

Before puberty, the testosterone level in boys is normally low. Testosterone increases during puberty. This causes boys to develop a deeper voice, get bigger muscles, make sperm , and get facial and body hair. The level of testosterone is the highest around age 40, then gradually becomes less in older men.

In women, the ovaries account for half of the testosterone in the body. Women have a much smaller amount of testosterone in their bodies compared to men. But testosterone plays an important role throughout the body in both men and women. It affects the brain, bone and muscle mass, fat distribution, the vascular system, energy levels, genital tissues, and sexual functioning.

Most of the testosterone in the blood is bound to a protein called sex hormone binding globulin (SHBG). Testosterone that is not bound (“free” testosterone) may be checked if a man or a woman is having sexual problems. Free testosterone also may be tested for a person who has a condition that can change SHBG levels, such as hyperthyroidism or some types of kidney diseases.

Total testosterone levels vary throughout the day. They are usually highest in the morning and lowest in the evening.

A testosterone test is done to:

You do not need to do anything before you have this test. Your doctor may want you to do a morning blood test because testosterone levels are highest between 7 a.m. and 9 a.m.

The health professional taking a sample of blood will:

The blood sample is taken from a vein in your arm. An elastic band is wrapped around your upper arm. It may feel tight. You may feel nothing at all from the needle, or you may feel a quick sting or pinch.

There is very little chance of a problem from having a blood sample taken from a vein.

A testosterone test checks the level of this male hormone (androgen) in the blood.

The normal values listed here-called a reference range-are just a guide. These ranges vary from lab to lab, and your lab may have a different range for what’s normal. Your lab report should contain the range your lab uses. Also, your doctor will evaluate your results based on your health and other factors. This means that a value that falls outside the normal values listed here may still be normal for you or your lab.

Your doctor will have your test results in a few days.

Men

270-1070 ng/dL (9-38 nmol/L)

Women

15-70 ng/dL (0.52-2.4 nmol/L)

Children (depends on sex and age at puberty)

2-20 ng/dL or 0.07-0.7 nmol/L

The testosterone level for a postmenopausal woman is about half the normal level for a healthy, nonpregnant woman. And a pregnant woman will have 3 to 4 times the amount of testosterone compared to a healthy, nonpregnant woman.

Men

50-210 pg/mL (174-729 pmol/L)

Women

Reasons you may not be able to have the test or why the results may not be helpful include:

To learn more, see:

Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.

Chernecky CC, Berger BJ (2008). Laboratory Tests and Diagnostic Procedures, 5th ed. St. Louis: Saunders.

Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.

Pagana KD, Pagana TJ (2010). Mosbys Manual of Diagnostic and Laboratory Tests, 4th ed. St. Louis: Mosby Elsevier.

ByHealthwise StaffPrimary Medical ReviewerE. Gregory Thompson, MD – Internal MedicineSpecialist Medical ReviewerAlan C. Dalkin, MD – Endocrinology

Current as ofNovember 20, 2015

WebMD Medical Reference from Healthwise

See the article here:
Testosterone(androgen) – WebMD


Sep 7

How short-term increases in testosterone change men’s thinking style – The British Psychological Society

In a guest post on our Research Digest blog, Emma Young looks at a new paper published in the journal Psychological Science.

Written bya team from Caltech, the University of Pennsylvania, Western University and the ZRT Laboratory in Oregon, it finds that a short-term rise in testosterone as might occur when in the presence of an attractive potential mateor during competition shifts the way men think. It encouragesthem to rely on quick, intuitive, and generally less accurate, judgements, rather than engaging in careful, more deliberate thought.

Our results demonstrate a clear and robust causal effect of testosterone on human cognition and decision making, the researchers write. The influence of testosterone on the Cognitive Reflection Test, alongside its lack of effect on the arithmetic control task, suggests that testosterone decreases the probability of engaging in slow and effortful cognitive processes but keeps the capacity to perform them intact.”

See the rest here:
How short-term increases in testosterone change men’s thinking style – The British Psychological Society



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