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A new report published in the journal Nature Medicine found that some patients who received human growth hormone from the pituitary glands of cadaver donors from 1959 to 1985 developed early cases of Alzheimers, possibly from contaminated samples that featured a protein associated with the disease. A handful of patients in the study displayed symptoms of early onset Alzheimers, with the youngest at 38 years old, and others were found to have the associated protein in their brains when they died. Researchers concluded that it is possible to develop Alzheimers from the transfer of a contaminated hormone, but they cautioned against overextending the scope of the results. Were not suggesting for a moment you can catch Alzheimers disease. This is not transmissible in the sense of a viral or bacterial infection, one of the co-authors of the study told the Guardian. The procedure that caused the patients in the study to degenerate has been discontinued for decades.

The rest is here:
Some Patients Got Early Alzheimer's From Contaminated HGH Treatment: Report - The Daily Beast

Many people believe that growth hormone is only for making muscles bigger or making skin smoother. But growth hormone can do much more than that. If you use it correctly, it can help you lose fat and get stronger, as well as improve your immunity and your sleep quality.

It also helps you stay energetic throughout the day. It also helps you recover faster and better from your workouts.

Here are the best HGH supplements:

1) HGH X2 Crazybulk: Click Here To Buy Overall the best HGH Supplement on the market

2) Ibuta 677: Click Here To Buy - Powerful GH Secretagogue for mass

3) GenF20 Plus: Click Here To Buy Clinically Proven HGH Supplement

4) HyperGH 14X: Click Here To Buy Natural HGH Releaser for Maximum Muscle Gains

5) Provacyl: Click Here To Buy Best overall Anti Aging supplement for Women

This is how Ibuta 677 can help you achieve more.

Bulking made easy

Staying fit all year is not easy. It needs a lot of hard work and discipline in your diet and exercise to keep your body mass.

Imagine you are eating a lot of calories every day. You need to watch out for gaining too much fat. You want to be lean even when you are bulking.

You need to change your lifting or your cardio, and adjust your diet. Everything has to be updated to make sure you keep gaining muscle.

But Ibuta 677 can make it easier for you by helping you stay full for longer and making muscle fibers faster and giving you anabolic support to keep your gains.

You will not even notice how easy it is to stay big all year-round.

Read More: Best HGH Supplements 4 Top Human Growth Pills - NASP Center

Lose fat while you gain weight

As we said, big gains do not have to be uneven and soft.

Ibuta 677 can help you keep your body lean and increase your muscle mass.

It increases your metabolism and helps control your hunger. It also helps increase fat burning in your body, which lets you get rid of the extra fat, without having to go back to crash diets.

This is because HGH can increase the amount of hormone sensitive lipase, an enzyme that is responsible for breaking down the fat in your fat cells.

So, you will stay healthy and fit without having to go back to crash diets or long exhausting exercises.

Improve blood flow and pump up your muscles

Muscle pumps are more than just temporary sugar-filled pumps. They help increase the size of muscle fibers, which makes them look bigger and harder.

By increasing the amount of GH in your body, Ibuta 677 can increase your blood vessels and improve your pumps.

This is because of the amino acids in the formula. The amino acids L-Glutamine and L-Citrulline Malate increase the amount of nitric oxide in your body, which leads to strong muscle pumps and increased blood flow.

You will be able to get a beautiful looking body easily and without having to use steroids or additives.

Ibuta-677 cost

Like the rest of the amazing collection from CrazyBulk, Ibuta 677 also costs $69/00 to buy a months supply. This is a great deal, folks. The price of the HGH enhancer prescribed by a doctor is $300 per month.

This way, you will get a cheap and safe way to build muscle and lose weight without having to worry about harmful side effects.

Also, buying for two months will give you the offer of one month. Basically, you buy a two-month supply and get three months of Ibuta 677."

Ibuta 677 - Our opinion

If you want to increase the amount of growth hormones in your body naturally, you can use Ibuta 677, which is a type of substance that stimulates the production of growth hormones. It is different from the usual growth hormone enhancers and it is a very good choice.

It helps you to gain more muscle and lose more fat easily and safely. It also makes your veins more visible and keeps you lean without using any legal hormones or steroids.

It does not matter if you are a beginner or an expert in bodybuilding, you will find something for you.

Why wait? Try CrazyBulks Ibuta-677 and take your body to the next level.

Click here to get the best price for Ibuta-677.

#4 - GenF20 Plus The best option for lubricating your joints during training

GenF20 Plus

One of the signs of getting old is having joint pain and cracking joints, which nobody likes.

As we age, this happens more often. You are running every day and then you hear a popping sound in your knees or hips, which makes you go to the doctor.

To avoid these problems, you need to be careful early on and make sure your joints are well-lubricated and healthy.

Look at GenF20 Plus, which is a supplement that releases growth hormone and improves the lubrication of your joints in your body. It is a supplement that has amino acids that increase the production of HGH in your body.

It also has deer antler velvet and L-arginine, which help to reduce joint stiffness and inflammation. When you use it regularly, you will see an improvement in your mobility and flexibility in a few weeks!

How does GenF20 Plus help joint health?

One of the main roles of growth hormone in your teenage years is to make your bones and cartilage grow, which also helps to keep your joints healthy.

As you get older, your body makes less of this important hormone and your joint health suffers. GenF20 Plus helps to reverse this by increasing the production of HGH in your body.

This leads to more bone density, which makes your bones stronger and more able to handle the wear and tear. It also helps to lower the swelling and inflammation in your joints, which makes you more mobile and flexible.

You also need to remember the role of GH in speeding up recovery. GH is one of the main hormones that is responsible for repairing and regenerating your muscles.

That is why you need to keep your GH levels high for the best performance at the gym and not worry about joint pain or stiffness. GenF20 Plus will help you do that!

The benefits of GenF20 Plus GenF20 Plus

If you are an athlete or someone who wants to stay fit, healthy, and active, you should focus on keeping your GH levels at their best.

GenF20 Plus helps you do that and also gives you many other benefits, such as more muscle mass, more energy, and better mood. You can expect to experience:

No more joint or muscle pain or soreness

For a long time, people thought that soreness was a sign of progress.

But the truth is that it will only slow you down and cause joint problems if you do not take care of it. GenF20 Plus helps to reduce the recovery time by lowering the muscle pain that lets you train more effectively.

It does this in many ways. It increases the healing speed of your ligaments and tendons, which makes them less prone to injuries. Its production of collagen and improves joint lubrication.

It also activates satellite cells, which help to heal and grow your muscles, which leads to better performance.

Healthier joints

One of the main reasons why athletes use GenF20 Plus is that it helps them reduce pain and swelling in their joints, making them more flexible and agile.

This happens because GenF20 Plus increases the thickness of the cartilage, which acts as a cushion between the joints. It also helps to make the joints more slippery, allowing smoother movement and less stiffness.

This way, you can do more exercises and push your body to the limit without worrying about getting hurt.

This can also improve your performance when you run or play sports. Do you have problems with your knees or elbows? You can avoid them by using GenF20 Plus!

More energy and mood

GenF20 Plus not only increases the production of GH in your body, but also balances other hormones like testosterone and IGF-1.

They are responsible for giving you more energy and a better mood. You can feel more focused and alert when you use GenF20 Plus, helping you to stay in shape.

Did you know that ATP is the main source of energy for your muscles? GenF20 Plus can help you produce more ATP in your body, which lets you work at your best every time.

The benefits of using GenF20 Plus for your joints and muscles are huge.

We have only talked about the joint health benefits of using GenF20 Plus, but it is also a great performance enhancer.

With almost a 200% increase in the natural production of GH, you can expect to see improvements in every aspect of your life.

GenF20 Plus Price

GenF20 Plus costs only $69.00 for a one-month supply. The best thing is that you dont have to buy a big package right away. You can start with one month and see how it works for you.

If you are happy with the results and want more, you can upgrade to bigger packages and get a lower price.

This makes GenF20 Plus one of the most affordable and effective ways to increase the production of GH in your body. But, the experts recommend that you take a GH supplement for at least 3 months before you notice any significant changes.

GenF20 Plus - Our opinion

GenF20 Plus is the best natural GH supplement in terms of quality and price.

It has many benefits, from healthier joints to faster muscle recovery - and it is supported by many research studies.

The fact that it is very cheap makes it even more attractive.

If you want to give your body needs to improve your performance, GenF20 Plus is the perfect choice for you! Check it out now and enjoy the benefits of increased GH production in just three months.

Click here to get the best price for GenF20 Plus"

#5 #5 Provacylthe best supplement for GH to reverse the effects of male menopause.

Provacyl

Some people say it is a hormone drop. We think that is too mild. The term male menopause might be the best way to describe what happens when mens testosterone and growth hormone levels start to go down.

Provacyl is a natural supplement that helps you keep your hormones balanced and reverse male menopause and improve your overall health and well-being.

It has been tested and shown to increase the levels of luteinizing hormone (LH) and growth hormone (GH) in men, which helps you get back your natural testosterone levels.

The main ingredients of Provacyl are a strong mix of amino acids and Deer Velvet Antler extract, both of which have been studied and proven to have positive effects on hormone balance.

The result is a big increase in not only growth hormone but also other male hormones in your body.

How can Provacyl help by reversing male menopause?

Male menopause is not accepted as a medical condition by the doctors, but it is a real problem that affects many men.

Provacyl helps you deal with this problem by increasing the levels of luteinizing hormone and growth hormone in your body.

These hormones are needed to make testosterone, which in turn helps you get back your energy and well-being.

The levels of growth hormone are closely linked to the levels of IGF-1. This is important for muscle growth, faster recovery and better heart health.

Also, Provacyl helps you lower the effects of cortisol on your body, reducing stress and helping you feel healthier.

In our current world, more and more people care about how they look, and they often go to the gym to improve their physical and social image.

Right now, it doesn't really matter if something is done to improve your health. Or just to get more followers on Instagram.

A good trend that is only seen as good is that more and more people realize that to look, feel and be healthy, you need to take care of your body and do active things.

One example is the fast growth of bodybuilding and fitness, which is not only for men but also for women.

But if you have ever tried to change how your body looks, you know how hard it is.

Muscle gain is not easy at all.

Some people choose to add anabolic steroids or HGH to their programs with the Human growth hormone (HGH) hoping to get better results and performance. This is just one of the many reasons for this.

Read this article:
HGH Over The Counter: Updated Insights into Accessing Human Growth Hormone Supplements - Deccan Herald

A new report published in the journal Nature Medicine found that some patients who received human growth hormone from the pituitary glands of cadaver donors from 1959 to 1985 developed early cases of Alzheimers, possibly from contaminated samples that featured a protein associated with the disease. A handful of patients in the study displayed symptoms of early onset Alzheimers, with the youngest at 38 years old, and others were found to have the associated protein in their brains when they died. Researchers concluded that it is possible to develop Alzheimers from the transfer of a contaminated hormone, but they cautioned against overextending the scope of the results. Were not suggesting for a moment you can catch Alzheimers disease. This is not transmissible in the sense of a viral or bacterial infection, one of the co-authors of the study told the Guardian. The procedure that caused the patients in the study to degenerate has been discontinued for decades.

Read it at The Guardian

Read more at The Daily Beast.

Read the rest here:
Some Patients Got Early Alzheimer's From Contaminated HGH Treatment: Report - Yahoo! Voices

Scientists believe that a rare medical treatment withdrawn in the 1980s may have caused some very rare cases of Alzheimer's.

Research published in the Nature Medicine journal suggests the individuals acquired a "rogue protein" that causes dementia from a growth hormone taken from the brains of deceased people, said Sky News.

Although the findings do not mean that Alzheimer's is infectious, the results could have significant implications for our understanding of dementia.

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Researchers studied eight people in the UK who, as children, received cadaver-derived human growth hormone (c-hGH) that had been extracted from the brains of human corpses.

At least 1,848 people received the c-hGH between the 1950s and 1980s. Some died from Creutzfeldt-Jakob disease (CJD), a degenerative brain condition, because the hormone infusions they received contained infectious proteins called prions that cause severe abnormalities in the brain. Prions are proteins that act like "seeds" of disease, explained Live Science, causing healthy proteins to "fold in abnormal, harmful ways".

The new findings indicate parallels between the evolution of Alzheimers and CJD. None of the eight patients in the new study had developed CJD, but five showed symptoms consistent with early-onset Alzheimer's. In three of the patients, biological and autopsy studies supported an Alzheimer's diagnosis, and they were suggestive in a fourth.

Alzheimer's disease is "the most common cause of dementia in the UK", said the NHS. An estimated one in 14 people over the age of 65 has Alzheimer's and other types of dementia, rising to one in six over the age of 80.

Alzheimer's is thought to be caused by the abnormal build-up of proteins in and around brain cells.

"We are not suggesting for a moment that you can catch Alzheimer's disease," said Professor John Collinge, of University College Londons Institute of Prion Diseases, as it is "not transmissible in the sense of a viral or bacterial infection".

Instead, said Live Science, the seed transfer linked to the Alzheimer's cases reported in the new study occurred in a "very specific and extraordinary medical context". And while "in theory", accidental transmissions of Alzheimer's seeds "could be possible in other medical procedures", steps are being taken to avoid any future repeats.

Dr Richard Oakley, associate director of research and innovation at Alzheimer's Society, told Science Media Centre that there was "no cause for concern for the health of the general population", and reiterated that the hormone treatment had not been used since 1985.

No, said Science News. Researchers "can't be certain" that contaminated growth hormone caused these people's Alzheimer's. It is possible that "the underlying childhood conditions that necessitated the growth hormone treatments", or "other medical procedures such as radiation", contributed to early Alzheimer's or cognitive problems.

As well as preventing similar transmissions, experts hope the findings might increase the understanding of dementia.

"One question is what can be done to stop such transmissions in future," said The Economist, and another is what the findings "might mean for treating Alzheimer's, even in people in whom the disease develops spontaneously".

The findings are a potential boost for research into diagnostics and therapies to combat all forms of dementia, as they might open up new treatment possibilities for a disease that is currently incurable.

The study has "revealed more about how amyloid fragments can spread within the brain", Dr Mava May, associate director of research at the Stroke Association, told Science Media Centre. This provides "further clues on how Alzheimer's disease progresses and potential new targets for the treatments of tomorrow".

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More:
How the transmission of Alzheimer's might be possible - The Week

Many people believe that growth hormone is only for making muscles bigger or improving skin health. But growth hormone has many other benefits besides these. If you use it correctly, it can help you lose fat and get more stamina, as well as strengthen your immune system and make you sleep better.

It also helps you stay energetic throughout the day. It also helps you recover faster and stronger from your workouts.

Here are the best HGH supplements:

1) HGH X2 Crazybulk: Click Here To Buy Overall the best HGH Supplement on the market

2) Ibuta 677: Click Here To Buy - Powerful GH Secretagogue for mass

3) GenF20 Plus: Click Here To Buy Clinically Proven HGH Supplement

4) HyperGH 14X: Click Here To Buy Natural HGH Releaser for Maximum Muscle Gains

5) Provacyl: Click Here To Buy Best overall Anti Aging supplement for Women

This is how Ibuta 677 can improve your results.

Bulking made easy

Staying fit all year is not easy. It needs a lot of hard work and discipline in your diet and exercise to keep your body weight.

Imagine you are eating more calories than you need every day. You have to watch out for gaining too much fat. You want to stay lean even when you are bulking.

You have to change your lifting or your cardio, and adjust your diet. Everything has to be updated to make sure you keep gaining muscle.

But, Ibuta 677 can make it easier for you by helping you stay full for longer and making muscle fibers faster and giving you anabolic support to keep your gains.

You will not even notice how easy it is to stay big all year-round.

Read More: Best HGH Supplements And Boosters 4 Top Human Growth Pills - NASP Center

Lose fat while you gain weight

As we said, big gains do not have to be uneven and soft.

Ibuta 677 can help you keep your body slim and increase your muscle.

It increases your metabolism and helps control your hunger. It also helps increase fat burning in your body, which lets you get rid of the extra fat, without having to go back to starving diets.

This is because HGH can increase the amount of hormone sensitive lipase, an enzyme that is responsible for breaking down the fat in your fat cells.

So, you will stay fit and toned without having to go back to extreme diets or long exhausting exercises.

Improve blood flow and pump up your muscles

Muscle pumps are more than just temporary sugar-filled pumps. They help increase the size of muscle fibers, which makes them look bigger and harder.

By increasing the amount of GH in your body, Ibuta 677 can increase your blood vessels and improve your pumps.

This is because of the amino acids in the formula. The amino acids L-Glutamine and L-Citrulline Malate increase the amount of nitric oxide in your body, which leads to strong muscle pumps and more blood flow.

You will be able to get a beautiful looking body easily and without having to use steroids or additives.

Ibuta-677 cost

Like the rest of the amazing collection from CrazyBulk, Ibuta 677 also costs $69/00 to buy a months supply. This is a great deal, folks. The price of the HGH enhancer prescribed by a doctor is $300 per month.

This way, you will get a cheap and safe way to build muscle and lose weight without having to worry about harmful side effects.

Also, buying for two months will give you the offer of one month. Basically, you buy a two-month supply and get three months of Ibuta 677.

Ibuta 677 - Our opinion

If you want to increase the amount of growth hormones that your body makes naturally, you can use Ibuta 677, which is a type of growth hormone-stimulator. It is better than the usual growth hormone-enhancers that you can find. It is a top-notch HGH product.

It helps you to gain more muscle and lose more fat easily and safely. It also makes your veins more visible and keeps you lean without using any legal hormones or steroids.

It does not matter if you are a beginner or an expert in bodybuilding, you will find something for you. Why wait any longer? Try CrazyBulks Ibuta-677 and take your body to the next level.

Click here to get the best price on Ibuta-677.

#4 - GenF20 Plus The best option for lubricating your joints during workouts

GenF20 Plus

One of the clear signs of ageing is having joint pain and noisy joints that nobody likes.

As we grow older, this happens more often. You are running every day and then you hear a cracking sound in your knees or hips, which makes you go to the doctor.

To avoid these problems, you need to be careful early on and make sure your joints are well-oiled and smooth.

Look at GenF20 Plus, which is a growth hormone-releaser that improves the lubrication of your joints all over your body. It is a supplement that has amino acids that boost the production of HGH in your body.

It also has velvet from deer antlers and L-arginine. This helps to lower the stiffness and inflammation of your joints. When you use it regularly, you will see an improvement in your movement and flexibility in just a few weeks!

One of the main roles of growth hormone in your teenage years is to make your bones and cartilage grow, which also helps to keep your joints healthy.

As you get older, your body makes less of this important hormone and your joint health suffers. GenF20 Plus helps to reverse this by increasing the production of HGH in your body.

This leads to more bone density, which makes your bones stronger and more able to handle the wear and tear. This also helps to reduce the swelling and inflammation of your joints, which makes you more mobile and flexible.

You also need to remember the role of GH in speeding up recovery. GH is one of the main hormones that is responsible for repairing and regenerating your muscles.

This is why you need to keep your GH levels high for the best performance at the gym and not worry about joint pain or stiffness. GenF20 Plus will help you do just that!

If you are an athlete, or someone who wants to stay fit, healthy, and active, you should focus on keeping your GH levels at their best.

GenF20 Plus helps you do that and also gives you many other benefits, such as more muscle mass, more energy, and better mood. You can expect to experience:

No more joint or muscle pain or soreness

For a long time, people thought that soreness was a sign of progress.

But the truth is that it will only slow you down and cause joint problems if you dont manage it well. GenF20 Plus helps to shorten the recovery time by reducing the muscle pain that lets you train more effectively.

It does this in many ways. It improves the healing of your ligaments and tendons, making them less prone to injuries. It also boosts the production of collagen and improves joint lubrication.

It also activates satellite cells, which help to heal and grow your muscles, resulting in better performance.

Better joint Lubrication

The main benefit of GenF20 Plus GenF20 Plus for athletes is that it reduces swelling and inflammation in joints and joints, making them more mobile and flexible.

This is accomplished by increasing the density of cartilage, which creates an enveloping layer between joints. It also assists in lubricating joints, allowing better movement and reduced stiffness.

In the end, you'll be able to do more repetitions as well as push the body to the limit without having to worry about injury.

This can also result in improved performance when running and playing sports. Runner's knee? Tennis elbow? All of these problems can be avoided by making use with GenF20 Plus!

GenF20 Plus is a supplement that helps your body make more GH, which is a hormone that affects many other hormones like testosterone and IGF-1.

These hormones make you feel more energetic and happy. You can also focus better and stay fit when you use GenF20 Plus.

Did you know that ATP is the main fuel for your muscles? GenF20 Plus can help your body produce more ATP, which lets you perform at your best every time.

GenF20 Plus is also great for your joints and muscles. It helps them heal faster and stay healthy.

GenF20 Plus is not just good for your joints and muscles, it can also improve your overall performance.

With almost double the amount of GH in your body, you can expect to do better in everything you do.

GenF20 Plus costs only $69.00 for one month. You dont have to buy a lot of it at once. You can start with one month and see how it works for you.

If you like the results and are happy, you can buy more and save money.

This makes GenF20 Plus one of the cheapest and most effective ways to increase GH in your body. But, the experts say that you should take a GH supplement for at least 3 months before you notice any big changes.

GenF20 Plus - Our opinion

GenF20 Plus is the best GH supplement you can find. It is natural and safe.

It has many benefits, from better joints and muscles, to more research support.

It is also very affordable and easy to get.

If you want to give your body a boost and improve your performance, GenF20 Plus is the perfect choice for you! Check it out now and enjoy the benefits of more GH in just 3 months.

Click here to get the best price for GenF20 Plus

#5 #5 Provacylthe best GH supplement to reverse the effects of male menopause.

Some people call it hormone drop. We think thats too mild. The term male menopause might be more accurate to describe what happens when mens testosterone and GH levels start to go down.

Provacyl is a natural supplement that helps you balance your hormones and reverse the effects of male menopause. It makes you feel healthier and happier.

It has been proven by science to increase the levels of luteinizing hormone (LH) and GH in men, which helps you restore your natural testosterone levels.

The main ingredients of Provacyl are a strong mix of amino acids and Deer Velvet Antler extract, both of which have been tested for their positive effects on hormone balance.

The result is a big increase in not only GH, but also other male hormones in your body.

Male menopause is not a recognized medical condition, but it is a real problem that affects many men.

Provacyl helps you deal with this problem by increasing the levels of LH and GH in your body.

These hormones are responsible for making testosterone, which helps you feel more energetic and well.

The levels of GH are also linked to the levels of IGF-1. This is important for muscle growth, faster recovery and better heart health.

Additionally, Provacyl helps to reduce the effects of cortisol on the body, decreasing stress levels and assisting men to feel healthier overall.

In our current environment growing numbers of people are placing greater importance on their outer appearance, and they are regularly making visits to the gym in order to improve their physical as well as their externally perceived traits.

At the moment it isn't really making an impact if something is done to improve the patient's health.Or just to increase the number of people who follow an individual on Instagram.

A positive trend that is only interpreted positively could be the reality that a growing percentage of folks are reaching the conclusion that to look, feel and feel healthy it is essential to take proper care of their bodies as well as take part in activities that are active.

One instance is the rapid growth in bodybuilding's popularity and bodybuilding, which is evident not just in males but also among females.

However If someone has ever had the opportunity to alter the appearance of their body you are aware of how difficult the process is.

Building muscle is not easy at all.

Some people choose to add HGH to their steroids or HGH plans to get better results in fitness and performance. This is one of the many reasons for doing this.

So, we will compare HGH and steroids in this article so you can understand how they are different and decide which one is better for you.

HGH

First, lets talk about HGH.

HGH stands for Human Growth Hormone. HGH is a natural hormone that your body makes. It is a strong hormone that helps you grow and develop. It also affects your muscles and bones. When the hormone is ready, the pituitary gland in your brain sends it to your blood to do its job.

When it gets to your blood, it goes to your liver. There, it helps increase the levels of other hormones in your body.

Some of them, especially testosterone, can help you build muscle.

Thats why people often use HGH with testosterone steroids like testosterone enanthate. HGH also does many other things. It also gives users many benefits, which we will talk about next.

See the original post:
HGH Over The Counter 2024: Exploring Access to Human Growth Hormone Supplements - Deccan Herald

In this new study, researchers indicate that between 1959 and 1985, at least 1,848 patients in the United Kingdom were treated with human growth hormones extracted from the pituitary glands of deceased donors, known as human cadaveric pituitary-derived growth hormone (c-hGH). Patients received these hormone injections several times per week, over the course of several months or years, to treat severe short stature and other conditions caused by hormone deficiencies.

The treatments were discontinued in 1985, after at least one patient treated with c-hGH died from iatrogenic CreutzfeldtJakob disease (iCJD), a rare but rapidly progressive and degenerative brain disease that is acquired when infectious brain proteins are accidentally transmitted to patients during medical or surgical procedures that use cadaveric tissue.

Researchers later tested archived batches of the c-hGH treatments and found they were contaminated with measurable quantities of AB seeding; precursors to developing Alzheimers disease.

According to findings published this week in the medical journal Nature Medicine, at least 200 cases of iCJD have been reported worldwide as a result of the contaminated treatments.

The researchers analyzed the medical history of eight individuals treated with c-hGH injections during different stages of childhood, who were referred to the National Prion Clinic (NPC) in the UK, which studies those diagnosed or at risk of developing brain diseases from the therapies.

At least five patients exhibited symptoms consistent with those seen with early-onset dementia, including progressive cognitive impairment, which developed between 38 and 55 years of age, between three and four decades after c-hGH exposure. Three of the five patients had been diagnosed with Alzheimers disease prior to be being referred to the clinic, and the other two patients presented symptoms seen among those with the disease, including memory loss, trouble communicating, and changes in behavior or personality.

Researchers reviewed brain scans of the patients, which showed progressive loss of brain tissue volume that are consistent with neurodegenerative diseases. Three of the eight study participants died, and autopsies revealed accumulations of infectious AB deposits in the brain, similar to those seen among those suffering from Alzheimers disease.

Genetic testing ruled out any potential genetic factors for developing adult-onset brain disorders, and the patients ages meant sporadic early-onset was unlikely, leading researchers to determine the new and progressive cognitive disturbances seen among the patients were the result of repeated c-hGH exposure. Among the study participants, at least four c-hGH recipients were diagnosed with confirmed Alzheimers disease, five met the standard definition for dementia, two with a clinical diagnosis of dementia were suspected to also have Alzheimers, and one had mild cognitive impairment, according to the findings.

The findings suggest Alzheimers disease can be transmitted in certain circumstances, such as during medical procedures. While there is no evidence that it can be transmitted to others during daily activities, researchers indicate further studies are needed to analyze exactly how this disease spreads. Researchers also indicate the findings warrant further preventative measures to avoid medically transmitted brain diseases, such as ensuring surgical instruments and other medical treatments are properly disinfected.

Link:
Growth Hormone Treatment May Have Transmitted Alzheimer's to Children, Study Warns - AboutLawsuits.com

Holy shit this sounds awesome! Well be there no matter what. From my research aka watching the Social Network I know Peter Thiel is the guy that invested in Facebook early on so Im just gonna assume hes very smart and that this plan will work smoothly!

Say what you want about the negative effects of steroids but seeing a bunch of elite athletes juiced to the gills competing and setting world records* (obviously with asterisks) would be incredible to watch. Literally the steroid era of baseball (by far the best, most fun era to watch) but with other sports? Count me in! I like the sports they listed but lets add a few more to the mix! How about baseball? They said combat sports but which ones? Wrestling? Boxing? MMA? Lets do all of the above! Lets take the greatest athletes this world has to offer and pump their bodies with steroids, HGH, whatever performance enhancers they can get their hands on! Lets see the maximum physical capabilities of the human body/mind. Rob McElhenney even wants to do a docuseries on it!

The behind the scenes would be amazing. Would basically be a real life version of the scenes leading up to the final fight in Rocky IV where Drago is basically being turned into a robot hooked up to all these wires on the treadmill and pumping anabolic steroids into his veins as hes hitting a punching bag with world record setting power. Im all in on this. No hiding from the truth. No BS. No such thing as a banned substance. Lets give the people what they want! (I really hope no one dies of a heart attack)

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A Group of Venture Capitalists Are Starting An Olympic-Style Competition That Would Allow Steroids, HGH And Other ... - Barstool Sports

Robina Weermeijer

By Isobel Williams via SWNS

A growth hormone given to children that was banned in 1985 has been shown to have caused Alzheimer's disease, a new study has revealed.

The hormone, derived from the pituitary gland of human corpses, was known as c-hGH or cadaver-derived human growth hormone.

It was used to treat at least 1,848 people of short stature in the UK between 1959 and 1985.

It was banned after some batches were contaminated with infectious proteins, or prions, which had caused Creutzfeldt-Jakob disease (CJD) a brain disease, in some people.

CJD normally proves fatal within eight months. A variant of CJD was known as mad cow disease

It has now been discovered that this treatment also left prematurely developed deposits of the amyloid-beta protein in participants brains, which is the cause of Alzheimers.

A team from University College London Hospital have now shown that at least five recipients of c-hGH developed Alzheimer's as a result.

Professor John Collinge from UCLH said: There is no suggestion whatsoever that Alzheimers disease can be transmitted between individuals during activities of daily life or routine medical care.

The patients we have described were given a specific and long-discontinued medical treatment which involved injecting patients with material now known to have been contaminated with disease-related proteins.

However, the recognition of transmission of amyloid-beta pathology in these rare situations should lead us to review measures to prevent accidental transmission via other medical or surgical procedures, in order to prevent such cases occurring in future.

Importantly, our findings also suggest that Alzheimer's and some other neurological conditions share similar disease processes to CJD, and this may have important implications for understanding and treating Alzheimers disease in the future.

Photo by cottonbro studio via Pexels

To get their results, published in the journal Nature Medicine, the team studied eight people referred to UCLHs National Prion Clinic at the National Hospital for Neurology and Neurosurgery in London, who had all been given this treatment in childhood.

They found that five of these people had symptoms of dementia, and either had already been diagnosed with Alzheimers disease or would meet the diagnostic criteria for this condition.

Another person was found to have met the criteria for mild cognitive impairment, and all these people were between 38 and 55 years old when they started having neurological symptoms.

The unusually young age at which these patients developed symptoms suggests they did not have the usual sporadic Alzheimers which is associated with old age.

In the five patients in whom samples were available for genetic testing, the team also ruled out inherited Alzheimers disease.

The researchers stress that this is extremely rare, and now that the treatment is no longer in use there is no risk of any new transmission.

Professor Jonathan Schott said: It is important to stress that the circumstances through which we believe these individuals tragically developed Alzheimers are highly unusual, and to reinforce that there is no risk that the disease can be spread between individuals or in routine medical care.

These findings do, however, provide potentially valuable insights into disease mechanisms, and pave the way for further research which we hope will further our understanding of the causes of more typical, late onset Alzheimers disease.

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Researchers find tie between banned growth hormone and Alzheimer's - NBC Right Now

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Alzheimers disease, a devastating neurological condition affecting people in late adulthood, may have been acquired by five individuals through medical treatments received decades ago. This marks the first instance of Alzheimers in living patients potentially linked to medical procedures.

The individuals in question were treated as children with cadaver-derived human growth hormone (c-hGH), extracted from the pituitary glands of deceased donors. This treatment was administered to at least 1,848 people in the UK between 1959 and 1985 for various forms of short stature. The practice was discontinued in 1985 after it was discovered that some batches of c-hGH were contaminated with infectious proteins called prions, responsible for Creutzfeldt-Jakob disease (CJD) in some patients. Fortunately, this medication was replaced a long time ago by synthetic growth hormone, which is free from the risk of transmitting CJD.

The same researchers previously found that some patients with CJD due to c-hGH treatment had also developed deposits of amyloid-beta protein in their brains prematurely. Further research in 2018 revealed that archived samples of c-hGH were contaminated with amyloid-beta protein. When injected into laboratory mice, these samples transmitted amyloid-beta pathology, suggesting that long-term survivors of c-hGH treatment might develop Alzheimers disease.

Amyloid-beta, a fragment produced from a larger precursor protein, is now considered a hallmark of Alzheimers. Patients with this condition have unusually high quantities of amyloid-beta in their brains.

In a healthy brain, amyloid-beta plays various roles, including regulating neural activity and supporting brain health. However, in Alzheimers disease, something goes awry. The protein begins to accumulate, forming clumps and eventually dense, insoluble plaques that disrupt brain function. This process is believed to be a critical factor in the onset and progression of Alzheimers, but the exact reasons why and how this accumulation occurs remain one of the great mysteries of modern neuroscience.

The new study focuses on eight individuals who received c-hGH treatment in childhood. The patients were admitted to the University College Londons National Prion Clinic at the National Hospital for Neurology and Neurosurgery. Among them, five displayed dementia symptoms consistent with Alzheimers disease or met the diagnostic criteria for it.

What is striking is their age range: 38 to 55 years when symptoms appeared, far younger than the typical onset age for sporadic Alzheimers in the mid-60s or later. Genetic testing ruled out inherited Alzheimers in these patients.

The c-hGH treatment is now obsolete, so there is no risk of new transmissions via this route. The authors of the study emphasize that the circumstances of these Alzheimers cases are highly unusual and that the disease cannot be spread through daily contact. There is no way you can get Alzheimers through close contact or routine care of a patient that was never a remote possibility.

However, now that this old treatment has been strongly linked to acquired Alzheimers, one can only wonder if other treatments, discontinued or otherwise, may also be responsible for Alzheimers.

The recognition of transmission of amyloid-beta pathology in these rare situations should lead us to review measures to prevent accidental transmission via other medical or surgical procedures, to prevent such cases from occurring in the future, said lead author Professor John Collinge, Director of the UCL Institute of Prion Diseases.

Importantly, our findings also suggest that Alzheimers and some other neurological conditions share similar disease processes to CJD, and this may have important implications for understanding and treating Alzheimers disease in the future.

The findings appeared in the journal Nature Medicine.

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Scientists document first cases of acquired Alzheimer's due to decades-old childhood treatment - ZME Science

LONDON A growth hormone administered to children, banned since 1985, is now displaying a link to Alzheimers disease. This hormone, extracted from the pituitary glands of human corpses, is called cadaver-derived human growth hormone (c-hGH). From 1959 to 1985, researchers in the United Kingdom say doctors administered it to at least 1,848 individuals dealing with growth deficiencies.

The use of c-hGH stopped after scientists discovered that some batches were contaminated with infectious proteins called prions. These contaminants were responsible for causing Creutzfeldt-Jakob disease (CJD), a fatal brain condition, among some recipients. CJD typically leads to death within eight months. A variant of CJD commonly goes by the name mad cow disease.

Recent findings indicate that this treatment also resulted in premature development of amyloid-beta protein deposits in the brains of participants, a known cause of Alzheimers disease. Researchers from University College London Hospital have now demonstrated that at least five individuals who received c-hGH subsequently developed Alzheimers as a consequence.

There is no suggestion whatsoever that Alzheimers disease can be transmitted between individuals during activities of daily life or routine medical care. The patients we have described were given a specific and long-discontinued medical treatment which involved injecting patients with material now known to have been contaminated with disease-related proteins, says study lead author Professor John Collinge, Director of the UCL Institute of Prion Diseases and a consultant neurologist at UCLH, in a media release.

However, the recognition of transmission of amyloid-beta pathology in these rare situations should lead us to review measures to prevent accidental transmission via other medical or surgical procedures, in order to prevent such cases occurring in future, Prof. Collinge continues.

Importantly, our findings also suggest that Alzheimers and some other neurological conditions share similar disease processes to CJD, and this may have important implications for understanding and treating Alzheimers disease in the future.

In their study, published in Nature Medicine, the researchers at University College London Hospitals National Prion Clinic, based at the National Hospital for Neurology and Neurosurgery in London, examined eight individuals. These individuals, who all received the controversial treatment during childhood, were referred to the clinic.

The team discovered that five of these individuals exhibited symptoms of dementia. They had either already been diagnosed with Alzheimers disease or met the diagnostic criteria for the condition. Additionally, another individual was identified as meeting the criteria for mild cognitive impairment. Notably, these patients were between 38 and 55 years-old when they first exhibited neurological symptoms, which is unusually young. This early onset of symptoms indicates that their condition differed from the typical sporadic Alzheimers disease, which is commonly associated with older age.

Furthermore, in the five patients for whom genetic testing samples were available, the researchers ruled out the possibility of inherited Alzheimers disease. The researchers emphasized that this situation is extremely rare. Additionally, they reassured us that since the implicated treatment is no longer in use, there is no risk of new cases arising from this cause.

It is important to stress that the circumstances through which we believe these individuals tragically developed Alzheimers are highly unusual, and to reinforce that there is no risk that the disease can be spread between individuals or in routine medical care, concludes study co-author Professor Jonathan Schott from the UCL Queen Square Institute of Neurology.

These findings do, however, provide potentially valuable insights into disease mechanisms, and pave the way for further research which we hope will further our understanding of the causes of more typical, late onset Alzheimers disease. South West News Service writer Isobel Williams contributed to this report.

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Banned growth hormone linked to Alzheimer's disease -- Former child patients at risk - Study Finds

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